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Trimethoxysilane chemical structure, C3H10O3Si, CAS 2487-90-3
2D chemical structure

Key facts

What buyers check first

Appearance
Liquid
Melting point
-115 °C
Boiling point
84 °C
Density
0.860 g/cm³ at 20 °C
Solubility
Hydrolyzes rapidly in water
HS code
292090
Category
Silanes and silicones
UN number
UN NA9269
Illustrative photo, closed blue jerry cans in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Trimethoxysilane?

Plain description, key identifiers and synonyms

Trimethoxysilane appears as a colorless liquid. Slightly soluble in water and denser than water. Hence floats on water. Very toxic by ingestion, inhalation or skin absorption. May also be corrosive to skin and eyes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
trimethoxysilane
CAS number
2487-90-3 CAS number cross-checked
EC number
219-637-2
Molecular formula
C3H10O3Si
InChIKey
YUYCVXFAYWRXLS-UHFFFAOYSA-N
InChI
InChI=1S/C3H10O3Si/c1-4-7(5-2)6-3/h7H,1-3H3
SMILES (canonical and isomeric)
CO[SiH](OC)OC

Synonyms

  • LS 330
  • Silane, trimethoxy-
  • Trimethoxy silane
  • trimethoxy-silane
  • Trimethoxysilane (>85%)
  • LMD 930, LS 330, SY 2012,
  • (MeO)3SiH

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Liquidexp.
Melting point
-115 °Cexp.
Boiling point
84 °Cexp.
Density
0.860 g/cm³ at 20 °Cexp.
Solubility
Hydrolyzes rapidly in waterexp.
Vapour pressure
76 mm Hg at 25 °C (ext)exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
122.20 g/molcalc.
Exact mass
122.0399 Dacalc.
LogP (octanol/water)
-0.36calc.
Topological polar surface area
27.69 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
7calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
342NFPA 704 rating

Hazard statements

  • H225Highly flammable liquid and vapour.
  • H261In contact with water releases flammable gas.
  • H302Harmful if swallowed.
  • H314Causes severe skin burns and eye damage.
  • H318Causes serious eye damage.
  • H319Causes serious eye irritation.
  • H330Fatal if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (36)
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P231 + P232Handle and store contents under inert gas. Protect from moisture.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P317If swallowed: Get medical help.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P337 + P317If eye irritation persists: Get medical help.
  • P363Wash contaminated clothing before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P402 + P404Store in a dry place. Store in a closed container.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN NA9269
Transport hazard class
6.1
Packing group
I

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Trimethoxysilane suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 16 suppliers
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Where suppliers are based

16 suppliers in 4 countries

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Trimethoxysilane price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Used to prepare a number of organic coupling agents utilized by the plastics industry as adhesion promotors.

Used in the industrial production of trimethoxysilylpropyl methacrylate [2530-85-0] by direct addition of trimethoxy silane in the presence of radical scavengers.

Used as an adhesive and bindings agent (92%), as an intermediate (7%) and as a surface active agent (1%).

Industrial uses: Adhesion/cohesion promoter, Intermediate.

How it is made

Reaction of silicon with ethanol or methanol containing less than 2000 ppm water produces trimethoxy silane with cuprous chloride as the catalyst.

Silane reacts with methanol at room temperature to produce ... trimethoxysilane.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Trimethoxysilane is traded under.

HS 2920.90Indicative HS code

Esters, other than thiophosphoric esters (phosphorothioates) and phosphite esters and their salts…

World exports in 2024
$1.05B
+8.0% vs 2023, imports $1.23B
2019 to 2024
Top exporters
  1. China33.4%
  2. Germany18.8%
  3. United States12.4%
Top importers
  1. United States19.2%
  2. Singapore8.9%
  3. South Korea6.9%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Trimethoxysilane is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Trimethoxysilane, based on the data on this page

What is Trimethoxysilane?

Trimethoxysilane appears as a colorless liquid. Slightly soluble in water and denser than water. Hence floats on water. Very toxic by ingestion, inhalation or skin absorption. May also be corrosive to skin and eyes.

What is the CAS number of Trimethoxysilane?

The CAS registry number of Trimethoxysilane is 2487-90-3.

What is the molecular formula and weight of Trimethoxysilane?

The molecular formula of Trimethoxysilane is C3H10O3Si and its molar mass is 122.20 g/mol.

What is Trimethoxysilane used for?

Used to prepare a number of organic coupling agents utilized by the plastics industry as adhesion promotors. Used in the industrial production of trimethoxysilylpropyl methacrylate [2530-85-0] by direct addition of trimethoxy silane in the presence of radical scavengers.

Is Trimethoxysilane hazardous?

Trimethoxysilane carries the GHS signal word "Danger". Main hazards: highly flammable liquid and vapour, in contact with water releases flammable gas, harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Trimethoxysilane?

Trimethoxysilane is usually classified under HS code 292090 (Esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Trimethoxysilane?

CompoundList lists 16 suppliers of Trimethoxysilane in China, United States, Germany and Netherlands. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Trimethoxysilane?

Suppliers quote Trimethoxysilane on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Trimethoxysilane

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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