Trimethoxysilane
Also known as LS 330, Silane, trimethoxy-, Trimethoxy silane
Key facts
What buyers check first
- Appearance
- Liquid
- Melting point
- -115 °C
- Boiling point
- 84 °C
- Density
- 0.860 g/cm³ at 20 °C
- Solubility
- Hydrolyzes rapidly in water
- HS code
- 292090
- Category
- Silanes and silicones
- UN number
- UN NA9269

What is Trimethoxysilane?
Plain description, key identifiers and synonyms
Trimethoxysilane appears as a colorless liquid. Slightly soluble in water and denser than water. Hence floats on water. Very toxic by ingestion, inhalation or skin absorption. May also be corrosive to skin and eyes.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- trimethoxysilane
- CAS number
- 2487-90-3 CAS number cross-checked
- EC number
- 219-637-2
- Molecular formula
- C3H10O3Si
- InChIKey
- YUYCVXFAYWRXLS-UHFFFAOYSA-N
- InChI
- InChI=1S/C3H10O3Si/c1-4-7(5-2)6-3/h7H,1-3H3
- SMILES (canonical and isomeric)
- CO[SiH](OC)OC
Synonyms
- LS 330
- Silane, trimethoxy-
- Trimethoxy silane
- trimethoxy-silane
- Trimethoxysilane (>85%)
- LMD 930, LS 330, SY 2012,
- (MeO)3SiH
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Liquidexp.Measured value |
|---|---|
| Melting point | -115 °Cexp.Measured value |
| Boiling point | 84 °Cexp.Measured value |
| Density | 0.860 g/cm³ at 20 °Cexp.Measured value |
| Solubility | Hydrolyzes rapidly in waterexp.Measured value |
| Vapour pressure | 76 mm Hg at 25 °C (ext)exp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 122.20 g/molcalc.Computed value |
|---|---|
| Exact mass | 122.0399 Dacalc.Computed value |
| LogP (octanol/water) | -0.36calc.Computed value |
| Topological polar surface area | 27.69 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 3calc.Computed value |
| Rotatable bonds | 3calc.Computed value |
| Heavy atoms | 7calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 1calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H225Highly flammable liquid and vapour.
- H261In contact with water releases flammable gas.
- H302Harmful if swallowed.
- H314Causes severe skin burns and eye damage.
- H318Causes serious eye damage.
- H319Causes serious eye irritation.
- H330Fatal if inhaled.
- H335May cause respiratory irritation.
Precautionary statements (36)
- P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P231 + P232Handle and store contents under inert gas. Protect from moisture.
- P233Keep container tightly closed.
- P240Ground and bond container and receiving equipment.
- P241Use explosion-proof electrical, ventilating and lighting equipment.
- P242Use non-sparking tools.
- P243Take action to prevent static discharges.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P284In case of inadequate ventilation wear respiratory protection.
- P301 + P317If swallowed: Get medical help.
- P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
- P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
- P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P316Get emergency medical help immediately.
- P317Get medical help.
- P319Get medical help if you feel unwell.
- P320Specific treatment is urgent (see supplemental first aid instructions on the label).
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P337 + P317If eye irritation persists: Get medical help.
- P363Wash contaminated clothing before reuse.
- P370 + P378In case of fire: Use appropriate media to extinguish.
- P402 + P404Store in a dry place. Store in a closed container.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P403 + P235Store in a well-ventilated place. Keep cool.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
- UN number
- UN NA9269
- Transport hazard class
- 6.1
- Packing group
- I
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidTrimethoxysilane suppliers
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Where suppliers are based
16 suppliers in 4 countries
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Trimethoxysilane price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Used to prepare a number of organic coupling agents utilized by the plastics industry as adhesion promotors.
Used in the industrial production of trimethoxysilylpropyl methacrylate [2530-85-0] by direct addition of trimethoxy silane in the presence of radical scavengers.
Used as an adhesive and bindings agent (92%), as an intermediate (7%) and as a surface active agent (1%).
Industrial uses: Adhesion/cohesion promoter, Intermediate.
How it is made
Reaction of silicon with ethanol or methanol containing less than 2000 ppm water produces trimethoxy silane with cuprous chloride as the catalyst.
Silane reacts with methanol at room temperature to produce ... trimethoxysilane.
Regulatory status
Inventories, regulations and trade controls that list this substance
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Trimethoxysilane is traded under.
Esters, other than thiophosphoric esters (phosphorothioates) and phosphite esters and their salts…
- China33.4%
- Germany18.8%
- United States12.4%
- United States19.2%
- Singapore8.9%
- South Korea6.9%
The HS code shown for Trimethoxysilane is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Trimethoxysilane, based on the data on this page
What is Trimethoxysilane?
What is the CAS number of Trimethoxysilane?
What is the molecular formula and weight of Trimethoxysilane?
What is Trimethoxysilane used for?
Is Trimethoxysilane hazardous?
What is the HS code of Trimethoxysilane?
Where can I buy Trimethoxysilane?
What is the price of Trimethoxysilane?
Guides for buyers
Practical guides that help when you source, ship or handle Trimethoxysilane
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, Trade and logisticsShipping dangerous goods: UN numbers, classes and packing groupsHow the UN dangerous goods system works for chemicals, from the nine classes and UN numbers to packing groups, UN packaging marks, labels, documents and segregation.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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