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Murcko scaffold

Ring system with 5 rings and 26 atoms

12 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
26
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CC(n2cccn2)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CC(n2cccn2)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

1-(9H-Fluoren-9-ylmethoxycarbonyl)-3-pyrazol-1-ylazetidine-3-carboxylic acid chemical structure, C22H19N3O4, CAS 2445792-59-4
1-(9H-Fluoren-9-ylmethoxycarbonyl)-3-pyrazol-1-ylazetidine-3-carboxylic acid
CAS 2445792-59-4C22H19N3O4
1-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)-1H-pyrazole-5-carboxylic acid chemical structure, C22H19N3O4, CAS 2243513-38-2
1-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)-1H-pyrazole-5-carboxylic acid
CAS 2243513-38-2C22H19N3O4
1-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)-1H-pyrazole-3-carboxylic acid chemical structure, C22H19N3O4, CAS 2705209-30-7
1-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)-1H-pyrazole-3-carboxylic acid
CAS 2705209-30-7C22H19N3O4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-(1H-pyrazol-1-yl)azetidin-3-yl)acetic acid chemical structure, C23H21N3O4, CAS 2839138-40-6
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-(1H-pyrazol-1-yl)azetidin-3-yl)acetic acid
CAS 2839138-40-6C23H21N3O4
1-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid chemical structure, C23H18F3N3O4, CAS 2639433-33-1
1-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
CAS 2639433-33-1C23H18F3N3O4
1-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)-1H-pyrazole-4-carboxylic acid chemical structure, C22H19N3O4, CAS 2639427-80-6
1-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)-1H-pyrazole-4-carboxylic acid
CAS 2639427-80-6C22H19N3O4
(9H-Fluoren-9-yl)methyl 3-(3-bromo-1H-pyrazol-1-yl)azetidine-1-carboxylate chemical structure, C21H18BrN3O2, CAS 2680848-55-7
(9H-Fluoren-9-yl)methyl 3-(3-bromo-1H-pyrazol-1-yl)azetidine-1-carboxylate
CAS 2680848-55-7C21H18BrN3O2
(9H-Fluoren-9-yl)methyl 3-(5-nitro-1H-pyrazol-1-yl)azetidine-1-carboxylate chemical structure, C21H18N4O4, CAS 2680744-19-6
(9H-Fluoren-9-yl)methyl 3-(5-nitro-1H-pyrazol-1-yl)azetidine-1-carboxylate
CAS 2680744-19-6C21H18N4O4
(9H-Fluoren-9-yl)methyl 3-(hydroxymethyl)-3-(1H-pyrazol-1-yl)azetidine-1-carboxylate chemical structure, C22H21N3O3, CAS 2764020-77-9
(9H-Fluoren-9-yl)methyl 3-(hydroxymethyl)-3-(1H-pyrazol-1-yl)azetidine-1-carboxylate
CAS 2764020-77-9C22H21N3O3
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-(4-iodo-1H-pyrazol-1-yl)azetidin-3-yl)acetic acid chemical structure, C23H20IN3O4, CAS 2901096-37-3
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-(4-iodo-1H-pyrazol-1-yl)azetidin-3-yl)acetic acid
CAS 2901096-37-3C23H20IN3O4
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-(3-iodo-1H-pyrazol-1-yl)azetidin-3-yl)acetic acid chemical structure, C23H20IN3O4, CAS 2901095-53-0
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-(3-iodo-1H-pyrazol-1-yl)azetidin-3-yl)acetic acid
CAS 2901095-53-0C23H20IN3O4
2-[3-(3-Bromo-1H-pyrazol-1-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl]acetic acid chemical structure, C23H20BrN3O4, CAS 2913409-25-1
2-[3-(3-Bromo-1H-pyrazol-1-yl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl]acetic acid
CAS 2913409-25-1C23H20BrN3O4