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Murcko scaffold

4-Oxa-tricyclo(4.2.1.0(3,7))nonan-5-one scaffold

35 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
10
Chemicals
35
With full pages
5
Scaffold SMILES

O=C1OC2CC3CC1C2C3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Oxa-tricyclo(4.2.1.0(3,7))nonan-5-one page
Murcko scaffold O=C1OC2CC3CC1C2C3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

6-Bromo-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxylic acid chemical structure, C9H9BrO4, CAS 7509-38-8
6-Bromo-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxylic acid
CAS 7509-38-8C9H9BrO4
2-Oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxylic acid chemical structure, C9H10O4, CAS 5411-71-2
2-Oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxylic acid
CAS 5411-71-2C9H10O4
4-Oxa-tricyclo(4.2.1.0(3,7))nonan-5-one chemical structure, C8H10O2, CAS 6712-12-5
4-Oxa-tricyclo(4.2.1.0(3,7))nonan-5-one
CAS 6712-12-5C8H10O2
6-Bromohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one chemical structure, C8H9BrO2, CAS 16512-03-1
6-Bromohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one
CAS 16512-03-1C8H9BrO2
6-Chlorohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one chemical structure, C8H9ClO2, CAS 35242-26-3
6-Chlorohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one
CAS 35242-26-3C8H9ClO2
7-Methylhexahydro-2H-3,5-methanocyclopenta[b]furan-2-one chemical structure, C9H12O2, CAS 24657-48-5
7-Methylhexahydro-2H-3,5-methanocyclopenta[b]furan-2-one
CAS 24657-48-5C9H12O2
6a-Methyl-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxylic acid chemical structure, C10H12O4, CAS 91109-82-9
6a-Methyl-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxylic acid
CAS 91109-82-9C10H12O4
6-Iodohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one chemical structure, C8H9IO2, CAS 14948-68-6
6-Iodohexahydro-2H-3,5-methanocyclopenta[b]furan-2-one
CAS 14948-68-6C8H9IO2
6-Iodo-7-methylhexahydro-2H-3,5-methanocyclopenta[b]furan-2-one chemical structure, C9H11IO2, CAS 26097-15-4
6-Iodo-7-methylhexahydro-2H-3,5-methanocyclopenta[b]furan-2-one
CAS 26097-15-4C9H11IO2
N,N-Diethyl-5-oxo-4-oxatricyclo[4.2.1.03,7]nonane-9-carboxamide chemical structure, C13H19NO3, CAS 84309-85-3
N,N-Diethyl-5-oxo-4-oxatricyclo[4.2.1.03,7]nonane-9-carboxamide
CAS 84309-85-3C13H19NO3
6-Hydroxyhexahydro-2H-3,5-methanocyclopenta(b)furan-2-one chemical structure, C8H10O3, CAS 92343-46-9
6-Hydroxyhexahydro-2H-3,5-methanocyclopenta(b)furan-2-one
CAS 92343-46-9C8H10O3
2-Iodo-5-oxo-4-oxa-tricyclo(4.2.1.0(3,7))nonane-9-carboxylic acid chemical structure, C9H9IO4, CAS 15573-45-2
2-Iodo-5-oxo-4-oxa-tricyclo(4.2.1.0(3,7))nonane-9-carboxylic acid
CAS 15573-45-2C9H9IO4
6-Hydroxy-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxylic acid chemical structure, C9H10O5, CAS 110013-49-5
6-Hydroxy-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-7-carboxylic acid
CAS 110013-49-5C9H10O5
(1S,2R,3S,6S,7S,9R)-2-Hydroxy-5-oxo-4-oxatricyclo[4.2.1.03,7]nonane-9-carboxylic acid chemical structure, C9H10O5, CAS 86259-08-7
(1S,2R,3S,6S,7S,9R)-2-Hydroxy-5-oxo-4-oxatricyclo[4.2.1.03,7]nonane-9-carboxylic acid
CAS 86259-08-7C9H10O5
3,5-Methano-2H-cyclopenta(b)furan-2-one, 6-bromohexahydro-, (3S-(3alpha,3abeta,5alpha,6beta,6abeta))- chemical structure, C8H9BrO2, CAS 123536-32-3
3,5-Methano-2H-cyclopenta(b)furan-2-one, 6-bromohexahydro-, (3S-(3alpha,3abeta,5alpha,6beta,6abeta))-
CAS 123536-32-3C8H9BrO2
6-Hydroxy-3-(trifluoromethyl)hexahydro-2H-3,5-methanocyclopenta[b]furan-2-one chemical structure, C9H9F3O3, CAS 787618-67-1
6-Hydroxy-3-(trifluoromethyl)hexahydro-2H-3,5-methanocyclopenta[b]furan-2-one
CAS 787618-67-1C9H9F3O3
3-Methylhexahydro-2H-3,5-methanocyclopenta[b]furan-2-one chemical structure, C9H12O2, CAS 38335-10-3
3-Methylhexahydro-2H-3,5-methanocyclopenta[b]furan-2-one
CAS 38335-10-3C9H12O2
(6-Cyano-5-oxo-4-oxatricyclo[4.2.1.03,7]nonan-2-yl) 2-methylprop-2-enoate chemical structure, C13H13NO4, CAS 926668-15-7
(6-Cyano-5-oxo-4-oxatricyclo[4.2.1.03,7]nonan-2-yl) 2-methylprop-2-enoate
CAS 926668-15-7C13H13NO4
6-Hydroxy-2-oxotetrahydro-2H-3,5-methanocyclopenta[b]furan-3(3aH)-carbonitrile chemical structure, C9H9NO3, CAS 931398-54-8
6-Hydroxy-2-oxotetrahydro-2H-3,5-methanocyclopenta[b]furan-3(3aH)-carbonitrile
CAS 931398-54-8C9H9NO3
2-Oxohexahydro-2H-3,5-methanocyclopenta[b]furan-6-yl Methacrylate chemical structure, C12H14O4, CAS 254900-07-7
2-Oxohexahydro-2H-3,5-methanocyclopenta[b]furan-6-yl Methacrylate
CAS 254900-07-7C12H14O4
Hexahydro-2-oxo-3,5-methano-2H-cyclopenta[b]furan-6-yl 2-propenoate chemical structure, C11H12O4, CAS 242129-35-7
Hexahydro-2-oxo-3,5-methano-2H-cyclopenta[b]furan-6-yl 2-propenoate
CAS 242129-35-7C11H12O4
3,5-Methano-2H-cyclopenta[b]furan-7-carboxylic acid, hexahydro-6-[(2-methyl-1-oxo-2-propen-1-yl)oxy]-2-oxo-, methyl ester chemical structure, C14H16O6, CAS 274247-93-7
3,5-Methano-2H-cyclopenta[b]furan-7-carboxylic acid, hexahydro-6-[(2-methyl-1-oxo-2-propen-1-yl)oxy]-2-oxo-, methyl ester
CAS 274247-93-7C14H16O6
Methyl 5-oxo-4-oxatricyclo[4.2.1.03,7]nonane-9-carboxylate chemical structure, C10H12O4, CAS 678992-76-2
Methyl 5-oxo-4-oxatricyclo[4.2.1.03,7]nonane-9-carboxylate
CAS 678992-76-2C10H12O4
7-Methoxycarbonyl-2-oxohexahydro-3,5-methano-2H-cyclopenta[b]furan-6-yl 2-(methacryloyloxy)-acetate chemical structure, C16H18O8, CAS 1004532-02-8
7-Methoxycarbonyl-2-oxohexahydro-3,5-methano-2H-cyclopenta[b]furan-6-yl 2-(methacryloyloxy)-acetate
CAS 1004532-02-8C16H18O8