CompoundList
Sign in
Murcko scaffold

N-[(2E)-5,5-Dioxido-3-phenyltetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide scaffold

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
12
With full pages
6
Scaffold SMILES

O=C(CCc1ccccc1)N=C1SC2CS(=O)(=O)CC2N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[(2E)-5,5-Dioxido-3-phenyltetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide page
Murcko scaffold O=C(CCc1ccccc1)N=C1SC2CS(=O)(=O)CC2N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

N-[(2E)-3-(3-Methoxyphenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C21H22N2O4S2, CAS 900293-78-9
N-[(2E)-3-(3-Methoxyphenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 900293-78-9C21H22N2O4S2
N-[(2E)-3-(4-Chlorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C20H19ClN2O3S2, CAS 900880-74-2
N-[(2E)-3-(4-Chlorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 900880-74-2C20H19ClN2O3S2
N-[(2Z)-3-(4-Methoxyphenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C21H22N2O4S2, CAS 900896-53-9
N-[(2Z)-3-(4-Methoxyphenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 900896-53-9C21H22N2O4S2
N-[(2Z)-3-(2-Methoxyphenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C21H22N2O4S2, CAS 900901-89-5
N-[(2Z)-3-(2-Methoxyphenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 900901-89-5C21H22N2O4S2
N-[(2E)-3-(2-Chlorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C20H19ClN2O3S2, CAS 900894-89-5
N-[(2E)-3-(2-Chlorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 900894-89-5C20H19ClN2O3S2
N-[(2E)-3-(4-Fluorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C20H19FN2O3S2, CAS 900889-08-9
N-[(2E)-3-(4-Fluorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 900889-08-9C20H19FN2O3S2
N-[(2E)-3-(2,4-Difluorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C20H18F2N2O3S2, CAS 900882-68-0
N-[(2E)-3-(2,4-Difluorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 900882-68-0C20H18F2N2O3S2
N-[(2E)-5,5-Dioxido-3-phenyltetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C20H20N2O3S2, CAS 900869-77-4
N-[(2E)-5,5-Dioxido-3-phenyltetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 900869-77-4C20H20N2O3S2
N-[(2E)-3-(2-Fluorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C20H19FN2O3S2, CAS 892636-84-9
N-[(2E)-3-(2-Fluorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 892636-84-9C20H19FN2O3S2
N-[(2E)-3-(3-Chlorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C20H19ClN2O3S2, CAS 902028-98-2
N-[(2E)-3-(3-Chlorophenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 902028-98-2C20H19ClN2O3S2
N-[(2E)-3-[4-(Dimethylamino)phenyl]-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C22H25N3O3S2, CAS 892624-85-0
N-[(2E)-3-[4-(Dimethylamino)phenyl]-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 892624-85-0C22H25N3O3S2
N-[(2Z)-3-(3-Butoxyphenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide chemical structure, C24H28N2O4S2, CAS 929834-53-7
N-[(2Z)-3-(3-Butoxyphenyl)-5,5-dioxidotetrahydrothieno[3,4-d][1,3]thiazol-2(3H)-ylidene]-3-phenylpropanamide
CAS 929834-53-7C24H28N2O4S2