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Murcko scaffold

Ring system with 5 rings and 37 atoms

20 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
37
Chemicals
20
With full pages
3
Scaffold SMILES

O=C(NCCCCN=CNS(=O)(=O)c1ccc2c(c1)CCO2)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCCCN=CNS(=O)(=O)c1ccc2c(c1)CCO2)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-alpha-Fmoc-N-omega-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzo[b]furan-5-ylsulfonyl)-L-beta-homoarginine chemical structure, C35H42N4O7S, CAS 401915-53-5
N-alpha-Fmoc-N-omega-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzo[b]furan-5-ylsulfonyl)-L-beta-homoarginine
CAS 401915-53-5C35H42N4O7S
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanoic acid chemical structure, C34H40N4O7S, CAS 1809177-30-7
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanoic acid
CAS 1809177-30-7C34H40N4O7S
N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine chemical structure, C34H40N4O7S, CAS 154445-77-9
N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
CAS 154445-77-9C34H40N4O7S
(2R)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-5-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}pentanoic acid chemical structure, C34H40N4O7S, CAS 187618-60-6
(2R)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-5-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}pentanoic acid
CAS 187618-60-6C34H40N4O7S
Fmoc-Arg(pbf)-H chemical structure, C34H40N4O6S, CAS 1026023-54-0
Fmoc-Arg(pbf)-H
CAS 1026023-54-0C34H40N4O6S
(3R)-6-[[Amino-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-3-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid chemical structure, C35H42N4O7S, CAS 1392219-39-4
(3R)-6-[[Amino-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-3-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
CAS 1392219-39-4C35H42N4O7S
Methyl (2S)-5-[[amino-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoate chemical structure, C35H42N4O7S, CAS 813452-47-0
Methyl (2S)-5-[[amino-[(2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoate
CAS 813452-47-0C35H42N4O7S
(S)-Fmoc-2-amino-5-[(N'-Pbf-N''-tert-butoxy)-guanidino]-pentanoic acid chemical structure, C38H48N4O8S, CAS 1060769-55-2
(S)-Fmoc-2-amino-5-[(N'-Pbf-N''-tert-butoxy)-guanidino]-pentanoic acid
CAS 1060769-55-2C38H48N4O8S
Fmoc-l-arg(me)2(pbf)-oh chemical structure, C36H44N4O7S, CAS 1185841-84-2
Fmoc-l-arg(me)2(pbf)-oh
CAS 1185841-84-2C36H44N4O7S
(S)-Fmoc-2-amino-5-[(N'-Pbf-N''-Boc-amino)-guanidino]-pentanoic acid chemical structure, C39H49N5O9S, CAS 1060769-54-1
(S)-Fmoc-2-amino-5-[(N'-Pbf-N''-Boc-amino)-guanidino]-pentanoic acid
CAS 1060769-54-1C39H49N5O9S
Fmoc-Arg(Pbf)-NH2 chemical structure, C34H41N5O6S, CAS 252348-72-4
Fmoc-Arg(Pbf)-NH2
CAS 252348-72-4C34H41N5O6S
Fmoc-N-Me-Arg(Pbf)-OH chemical structure, C35H42N4O7S, CAS 913733-27-4
Fmoc-N-Me-Arg(Pbf)-OH
CAS 913733-27-4C35H42N4O7S
Fmoc-Arg(Pbf)-Gly-OH chemical structure, C36H43N5O8S, CAS 660846-80-0
Fmoc-Arg(Pbf)-Gly-OH
CAS 660846-80-0C36H43N5O8S
Fmoc-N-Me-D-Arg(pbf)-OH chemical structure, C35H42N4O7S, CAS 2044710-57-6
Fmoc-N-Me-D-Arg(pbf)-OH
CAS 2044710-57-6C35H42N4O7S
Fmoc-Arg(pbf)-OL chemical structure, C34H42N4O6S, CAS 260450-75-7
Fmoc-Arg(pbf)-OL
CAS 260450-75-7C34H42N4O6S
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-NW-methyl-NW-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)-D-arginine chemical structure, C35H42N4O7S
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-NW-methyl-NW-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)-D-arginine
C35H42N4O7S
Fmoc-D-Arg(Me,pbf)-OH chemical structure, C35H42N4O7S, CAS 2044711-16-0
Fmoc-D-Arg(Me,pbf)-OH
CAS 2044711-16-0C35H42N4O7S
Fmoc-alpha-ME-L-arg(pbf)-OH chemical structure, C35H42N4O7S, CAS 2124196-74-1
Fmoc-alpha-ME-L-arg(pbf)-OH
CAS 2124196-74-1C35H42N4O7S
Fmoc-L-Arg(t-Bu,Pbf)-OH chemical structure, C38H48N4O7S, CAS 1060769-44-9
Fmoc-L-Arg(t-Bu,Pbf)-OH
CAS 1060769-44-9C38H48N4O7S
Fmoc-Arg(Pbf)-OEt chemical structure, C36H44N4O7S, CAS 813452-90-3
Fmoc-Arg(Pbf)-OEt
CAS 813452-90-3C36H44N4O7S