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Murcko scaffold

Ring system with 4 rings and 22 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
10
With full pages
2
Scaffold SMILES

O=C1Nc2ccccc2C1=Cc1nc2ccccc2c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2ccccc2C1=Cc1nc2ccccc2c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-[(Z)-(1-Ethyl-2-oxoindol-3-ylidene)methyl]-3-methylquinazolin-4-one chemical structure, C20H17N3O2, CAS 352656-78-1
2-[(Z)-(1-Ethyl-2-oxoindol-3-ylidene)methyl]-3-methylquinazolin-4-one
CAS 352656-78-1C20H17N3O2
2-[(Z)-(5-Bromo-1-methyl-2-oxoindol-3-ylidene)methyl]-3-methylquinazolin-4-one chemical structure, C19H14BrN3O2, CAS 362004-54-4
2-[(Z)-(5-Bromo-1-methyl-2-oxoindol-3-ylidene)methyl]-3-methylquinazolin-4-one
CAS 362004-54-4C19H14BrN3O2
2-[(Z)-(1-Ethyl-2-oxoindol-3-ylidene)methyl]-3-(3-hydroxypropyl)quinazolin-4-one chemical structure, C22H21N3O3, CAS 430471-34-4
2-[(Z)-(1-Ethyl-2-oxoindol-3-ylidene)methyl]-3-(3-hydroxypropyl)quinazolin-4-one
CAS 430471-34-4C22H21N3O3
3-(3-Hydroxypropyl)-2-[(Z)-(1-methyl-2-oxoindol-3-ylidene)methyl]quinazolin-4-one chemical structure, C21H19N3O3, CAS 431884-26-3
3-(3-Hydroxypropyl)-2-[(Z)-(1-methyl-2-oxoindol-3-ylidene)methyl]quinazolin-4-one
CAS 431884-26-3C21H19N3O3
6-Iodo-3-methyl-2-[(Z)-(1-methyl-2-oxoindol-3-ylidene)methyl]quinazolin-4-one chemical structure, C19H14IN3O2, CAS 378207-50-2
6-Iodo-3-methyl-2-[(Z)-(1-methyl-2-oxoindol-3-ylidene)methyl]quinazolin-4-one
CAS 378207-50-2C19H14IN3O2
2-[(5-Bromo-2-oxo-1-propyl-1,2-dihydro-3H-indol-3-ylidene)methyl]-3-ethyl-4(3H)-quinazolinone chemical structure, C22H20BrN3O2, CAS 371924-94-6
2-[(5-Bromo-2-oxo-1-propyl-1,2-dihydro-3H-indol-3-ylidene)methyl]-3-ethyl-4(3H)-quinazolinone
CAS 371924-94-6C22H20BrN3O2
3-Ethyl-2-[(Z)-(2-oxo-1-propan-2-ylindol-3-ylidene)methyl]quinazolin-4-one chemical structure, C22H21N3O2, CAS 364619-34-1
3-Ethyl-2-[(Z)-(2-oxo-1-propan-2-ylindol-3-ylidene)methyl]quinazolin-4-one
CAS 364619-34-1C22H21N3O2
3-Ethyl-2-[(Z)-(2-oxo-1-propylindol-3-ylidene)methyl]quinazolin-4-one chemical structure, C22H21N3O2, CAS 334505-99-6
3-Ethyl-2-[(Z)-(2-oxo-1-propylindol-3-ylidene)methyl]quinazolin-4-one
CAS 334505-99-6C22H21N3O2
2-[(E)-(1-Ethyl-2-oxoindol-3-ylidene)methyl]-1H-quinazolin-4-one chemical structure, C19H15N3O2, CAS 1164455-87-1
2-[(E)-(1-Ethyl-2-oxoindol-3-ylidene)methyl]-1H-quinazolin-4-one
CAS 1164455-87-1C19H15N3O2
2-[(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-3-methyl-4(3H)-quinazolinone chemical structure, C18H12BrN3O2, CAS 350995-16-3
2-[(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-3-methyl-4(3H)-quinazolinone
CAS 350995-16-3C18H12BrN3O2