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Murcko scaffold

Ring system with 4 rings and 28 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
8
With full pages
2
Scaffold SMILES

O=C(NCc1nc2ccccc2c(=O)n1Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1nc2ccccc2c(=O)n1Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Ispinesib mesylate chemical structure, C31H37ClN4O5S, CAS 514820-03-2
Ispinesib mesylate
CAS 514820-03-2C31H37ClN4O5S
Ispinesib chemical structure, C30H33ClN4O2, CAS 336113-53-2
Ispinesib
CAS 336113-53-2C30H33ClN4O2
Benzamide, 4-bromo-N-(1-(7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl)propyl)-N-(3-(dimethylamino)propyl)- chemical structure, C30H32BrClN4O2, CAS 336115-72-1
Benzamide, 4-bromo-N-(1-(7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl)propyl)-N-(3-(dimethylamino)propyl)-
CAS 336115-72-1C30H32BrClN4O2
Anticancer agent 95 chemical structure, C30H32ClN5O3, CAS 853302-91-7
Anticancer agent 95
CAS 853302-91-7C30H32ClN5O3
Carbamic acid, [3-[[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl](4-methylbenzoyl)amino]propyl]-, 1,1-dimethylethyl ester chemical structure, C35H41ClN4O4, CAS 587881-28-5
Carbamic acid, [3-[[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl](4-methylbenzoyl)amino]propyl]-, 1,1-dimethylethyl ester
CAS 587881-28-5C35H41ClN4O4
(R)-N-(1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide chemical structure, C30H32BrClN4O2, CAS 709039-94-1
(R)-N-(1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide
CAS 709039-94-1C30H32BrClN4O2
(R)-tert-Butyl (3-(N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamido)propyl)carbamate chemical structure, C35H41ClN4O4
(R)-tert-Butyl (3-(N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)-2-methylpropyl)-4-methylbenzamido)propyl)carbamate
C35H41ClN4O4
N-(3-Aminopropyl)-N-[(1S)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl]-4-methylbenzamide chemical structure, C30H33ClN4O2, CAS 336113-54-3
N-(3-Aminopropyl)-N-[(1S)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl]-4-methylbenzamide
CAS 336113-54-3C30H33ClN4O2