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Murcko scaffold

2-(1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxo-N-phenethylacetamide scaffold

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
31
Chemicals
6
With full pages
5
Scaffold SMILES

O=C(NCCc1ccccc1)C(=O)c1cn(CC(=O)N2CCOCC2)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxo-N-phenethylacetamide page
Murcko scaffold O=C(NCCc1ccccc1)C(=O)c1cn(CC(=O)N2CCOCC2)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-(1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxo-N-phenethylacetamide chemical structure, C24H25N3O4, CAS 872856-98-9
2-(1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxo-N-phenethylacetamide
CAS 872856-98-9C24H25N3O4
N-(2-Methoxyphenethyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C25H27N3O5, CAS 872856-99-0
N-(2-Methoxyphenethyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872856-99-0C25H27N3O5
N-(4-Methoxyphenethyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C25H27N3O5, CAS 872857-01-7
N-(4-Methoxyphenethyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872857-01-7C25H27N3O5
N-(3,4-Dimethoxyphenethyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide chemical structure, C26H29N3O6, CAS 872857-00-6
N-(3,4-Dimethoxyphenethyl)-2-(1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxoacetamide
CAS 872857-00-6C26H29N3O6
N-(1,1-Dimethyl-2-phenyl-ethyl)-2-keto-2-[1-(2-keto-2-morpholino-ethyl)indol-3-yl]acetamide chemical structure, C26H29N3O4, CAS 893996-03-7
N-(1,1-Dimethyl-2-phenyl-ethyl)-2-keto-2-[1-(2-keto-2-morpholino-ethyl)indol-3-yl]acetamide
CAS 893996-03-7C26H29N3O4
2-(1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxo-N-(4-sulfamoylphenethyl)acetamide chemical structure, C24H26N4O6S, CAS 893995-07-8
2-(1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)-2-oxo-N-(4-sulfamoylphenethyl)acetamide
CAS 893995-07-8C24H26N4O6S