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Murcko scaffold

Ring system with 4 rings and 29 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
8
With full pages
3
Scaffold SMILES

N=C(NS(=O)(=O)c1ccccc1)N1CC(c2ccccc2)C(c2ccccc2)=N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold N=C(NS(=O)(=O)c1ccccc1)N1CC(c2ccccc2)C(c2ccccc2)=N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Ibipinabant chemical structure, C23H20Cl2N4O2S, CAS 464213-10-3
Ibipinabant
CAS 464213-10-3C23H20Cl2N4O2S
Slv319 chemical structure, C23H20Cl2N4O2S, CAS 362519-49-1
Slv319
CAS 362519-49-1C23H20Cl2N4O2S
(4S)-5-(4-Chlorophenyl)-N'-methyl-4-phenyl-N-[4-(trifluoromethyl)phenyl]sulfonyl-3,4-dihydropyrazole-2-carboximidamide chemical structure, C24H20ClF3N4O2S, CAS 464213-13-6
(4S)-5-(4-Chlorophenyl)-N'-methyl-4-phenyl-N-[4-(trifluoromethyl)phenyl]sulfonyl-3,4-dihydropyrazole-2-carboximidamide
CAS 464213-13-6C24H20ClF3N4O2S
(R)-3-(4-Chlorophenyl)-N-((4-chlorophenyl)sulfonyl)-N'-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide chemical structure, C23H20Cl2N4O2S, CAS 656827-86-0
(R)-3-(4-Chlorophenyl)-N-((4-chlorophenyl)sulfonyl)-N'-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide
CAS 656827-86-0C23H20Cl2N4O2S
5-(4-Chlorophenyl)-N'-methyl-4-phenyl-N-[3-(trifluoromethyl)phenyl]sulfonyl-3,4-dihydropyrazole-2-carboximidamide chemical structure, C24H20ClF3N4O2S, CAS 656827-75-7
5-(4-Chlorophenyl)-N'-methyl-4-phenyl-N-[3-(trifluoromethyl)phenyl]sulfonyl-3,4-dihydropyrazole-2-carboximidamide
CAS 656827-75-7C24H20ClF3N4O2S
2-[[[(4S)-3-(4-Chlorophenyl)-4,5-dihydro-4-phenyl-1H-pyrazol-1-yl][[(4-chlorophenyl)sulfonyl]amino]methylene]amino]-acetamide chemical structure, C24H21Cl2N5O3S, CAS 1404117-64-1
2-[[[(4S)-3-(4-Chlorophenyl)-4,5-dihydro-4-phenyl-1H-pyrazol-1-yl][[(4-chlorophenyl)sulfonyl]amino]methylene]amino]-acetamide
CAS 1404117-64-1C24H21Cl2N5O3S
JD-5037 chemical structure, C27H27Cl2N5O3S, CAS 1392116-14-1
JD-5037
CAS 1392116-14-1C27H27Cl2N5O3S
(2S)-2-{[(4-Chlorobenzenesulfonamido)[(4R)-3-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-1-yl]methylidene]amino}-3-methylbutanamide chemical structure, C27H27Cl2N5O3S, CAS 1404117-65-2
(2S)-2-{[(4-Chlorobenzenesulfonamido)[(4R)-3-(4-chlorophenyl)-4-phenyl-4,5-dihydro-1H-pyrazol-1-yl]methylidene]amino}-3-methylbutanamide
CAS 1404117-65-2C27H27Cl2N5O3S