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Murcko scaffold

Ring system with 6 rings and 30 atoms

8 chemicals on CompoundList share this ring system.

Rings
6
Scaffold atoms
30
Chemicals
8
With full pages
5
Scaffold SMILES

O=C1NCc2nc3ccccc3c(=O)n2C1CC1c2ccccc2N2C(=O)CNC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NCc2nc3ccccc3c(=O)n2C1CC1c2ccccc2N2C(=O)CNC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Fumiquinazoline E chemical structure, C25H25N5O5, CAS 140715-87-3
Fumiquinazoline E
CAS 140715-87-3C25H25N5O5
Fiscalin A chemical structure, C26H27N5O4, CAS 149030-11-5
Fiscalin A
CAS 149030-11-5C26H27N5O4
Fiscalin C chemical structure, C27H29N5O4, CAS 149008-36-6
Fiscalin C
CAS 149008-36-6C27H29N5O4
Fumiquinazoline I chemical structure, C27H29N5O4, CAS 278184-56-8
Fumiquinazoline I
CAS 278184-56-8C27H29N5O4
(1S,4R)-1-Methyl-4-(((2S,9S,9aS)-2,3,9,9a-tetrahydro-9-hydroxy-2-methyl-3-oxo-1H-imidazo(1,2-a)indol-9-yl)methyl)-2H-pyrazino(2,1-b)quinazoline-3,6(1H,4H)-dione chemical structure, C24H23N5O4, CAS 140715-85-1
(1S,4R)-1-Methyl-4-(((2S,9S,9aS)-2,3,9,9a-tetrahydro-9-hydroxy-2-methyl-3-oxo-1H-imidazo(1,2-a)indol-9-yl)methyl)-2H-pyrazino(2,1-b)quinazoline-3,6(1H,4H)-dione
CAS 140715-85-1C24H23N5O4
Fumiquinazoline B chemical structure, C24H23N5O4, CAS 140852-71-7
Fumiquinazoline B
CAS 140852-71-7C24H23N5O4
3-Hydroxyfumiquinazoline A chemical structure, C24H23N5O5, CAS 140715-88-4
3-Hydroxyfumiquinazoline A
CAS 140715-88-4C24H23N5O5
2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione, 1-hydroxy-1-(1-methylethyl)-4-[(2,3,9,9a-tetrahydro- chemical structure, C27H29N5O5, CAS 2058424-34-1
2H-Pyrazino[2,1-b]quinazoline-3,6(1H,4H)-dione, 1-hydroxy-1-(1-methylethyl)-4-[(2,3,9,9a-tetrahydro-
CAS 2058424-34-1C27H29N5O5