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Murcko scaffold

Ring system with 5 rings and 30 atoms

10 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
30
Chemicals
10
With full pages
2
Scaffold SMILES

O=C(CC1CCNCC1)N1CCC(C2c3ccccc3CCc3cccnc32)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CC1CCNCC1)N1CCC(C2c3ccccc3CCc3cccnc32)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Lonafarnib chemical structure, C27H31Br2ClN4O2, CAS 193275-84-2
Lonafarnib
CAS 193275-84-2C27H31Br2ClN4O2
(R)-1-(4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl)-2-(piperidin-4-yl)ethanone chemical structure, C26H30Br2ClN3O, CAS 193276-77-6
(R)-1-(4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl)-2-(piperidin-4-yl)ethanone
CAS 193276-77-6C26H30Br2ClN3O
4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidineacetamide chemical structure, C28H33Br2ClN4O2, CAS 204251-45-6
4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidineacetamide
CAS 204251-45-6C28H33Br2ClN4O2
4-{2-[4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-B]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide chemical structure, C27H31Br2ClN4O2, CAS 193275-86-4
4-{2-[4-(3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-B]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide
CAS 193275-86-4C27H31Br2ClN4O2
(R)-tert-Butyl 4-(2-(4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl)-2-oxoethyl)piperidine-1-carboxylate chemical structure, C31H38Br2ClN3O3, CAS 193276-76-5
(R)-tert-Butyl 4-(2-(4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl)-2-oxoethyl)piperidine-1-carboxylate
CAS 193276-76-5C31H38Br2ClN3O3
4-[2-[4-[(2S)-6,15-Dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide chemical structure, C27H31Br2ClN4O2, CAS 193275-85-3
4-[2-[4-[(2S)-6,15-Dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide
CAS 193275-85-3C27H31Br2ClN4O2
Lonafarnib metabolite A chemical structure, C27H31Br2ClN4O3, CAS 817202-01-0
Lonafarnib metabolite A
CAS 817202-01-0C27H31Br2ClN4O3
Lonafarnib D9 chemical structure, C27H31Br2ClN4O2, CAS 1197367-02-4
Lonafarnib D9
CAS 1197367-02-4C27H31Br2ClN4O2
1-{4-[(2S)-6,15-Dibromo-13-chloro-4-azatricyclo[9.4.0.0]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl]piperidin-1-yl}-2-(piperidin-4-yl)ethan-1-one chemical structure, C26H30Br2ClN3O, CAS 1099484-75-9
1-{4-[(2S)-6,15-Dibromo-13-chloro-4-azatricyclo[9.4.0.0]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl]piperidin-1-yl}-2-(piperidin-4-yl)ethan-1-one
CAS 1099484-75-9C26H30Br2ClN3O
RSV fusion glycoprotein inhibitor CGR-51 chemical structure, C27H30Br2ClFN4O2, CAS 3098857-57-6
RSV fusion glycoprotein inhibitor CGR-51
CAS 3098857-57-6C27H30Br2ClFN4O2