CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 21 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
10
With full pages
6
Scaffold SMILES

O=c1c(=Cc2ccccc2)sc2nc(-c3cccs3)nn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(=Cc2ccccc2)sc2nc(-c3cccs3)nn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

(5Z)-5-[[3-Methoxy-4-(3-methylbutoxy)phenyl]methylidene]-2-thiophen-2-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one chemical structure, C21H21N3O3S2, CAS 380580-23-4
(5Z)-5-[[3-Methoxy-4-(3-methylbutoxy)phenyl]methylidene]-2-thiophen-2-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
CAS 380580-23-4C21H21N3O3S2
(5Z)-5-[(4-Prop-2-enoxyphenyl)methylidene]-2-thiophen-2-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one chemical structure, C18H13N3O2S2, CAS 381171-99-9
(5Z)-5-[(4-Prop-2-enoxyphenyl)methylidene]-2-thiophen-2-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
CAS 381171-99-9C18H13N3O2S2
(5Z)-5-(3-Ethoxy-4-propoxybenzylidene)-2-(2-thienyl)[1,3]thiazolo[3,2-B][1,2,4]triazol-6(5H)-one chemical structure, C20H19N3O3S2, CAS 617694-42-5
(5Z)-5-(3-Ethoxy-4-propoxybenzylidene)-2-(2-thienyl)[1,3]thiazolo[3,2-B][1,2,4]triazol-6(5H)-one
CAS 617694-42-5C20H19N3O3S2
(5Z)-5-[(4-Propoxyphenyl)methylidene]-2-thiophen-2-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one chemical structure, C18H15N3O2S2, CAS 381200-86-8
(5Z)-5-[(4-Propoxyphenyl)methylidene]-2-thiophen-2-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
CAS 381200-86-8C18H15N3O2S2
(5Z)-5-(3,4-Diethoxybenzylidene)-2-(2-thienyl)[1,3]thiazolo[3,2-B][1,2,4]triazol-6(5H)-one chemical structure, C19H17N3O3S2, CAS 617694-29-8
(5Z)-5-(3,4-Diethoxybenzylidene)-2-(2-thienyl)[1,3]thiazolo[3,2-B][1,2,4]triazol-6(5H)-one
CAS 617694-29-8C19H17N3O3S2
(5Z)-5-(2-Butoxybenzylidene)-2-thien-2-yl[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one chemical structure, C19H17N3O2S2, CAS 608120-04-3
(5Z)-5-(2-Butoxybenzylidene)-2-thien-2-yl[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
CAS 608120-04-3C19H17N3O2S2
(5E)-5-(2-(Hexyloxy)benzylidene)-2-(2-thienyl)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one chemical structure, C21H21N3O2S2, CAS 617695-16-6
(5E)-5-(2-(Hexyloxy)benzylidene)-2-(2-thienyl)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one
CAS 617695-16-6C21H21N3O2S2
(5Z)-5-(2-Propoxybenzylidene)-2-(2-thienyl)[1,3]thiazolo[3,2-B][1,2,4]triazol-6(5H)-one chemical structure, C18H15N3O2S2, CAS 609794-86-7
(5Z)-5-(2-Propoxybenzylidene)-2-(2-thienyl)[1,3]thiazolo[3,2-B][1,2,4]triazol-6(5H)-one
CAS 609794-86-7C18H15N3O2S2
(5E)-5-(2-(Pentyloxy)benzylidene)-2-(2-thienyl)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one chemical structure, C20H19N3O2S2, CAS 617694-62-9
(5E)-5-(2-(Pentyloxy)benzylidene)-2-(2-thienyl)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one
CAS 617694-62-9C20H19N3O2S2
(5Z)-5-[(4-Iodophenyl)methylidene]-2-thiophen-2-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one chemical structure, C15H8IN3OS2, CAS 606957-76-0
(5Z)-5-[(4-Iodophenyl)methylidene]-2-thiophen-2-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
CAS 606957-76-0C15H8IN3OS2