Murcko scaffold

Ring system with 4 rings and 25 atoms

30 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 25
Chemicals: 30
With full pages: 19

Scaffold SMILES

N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NCc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NCc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

N-(2-Furylmethyl)-2-imino-1-(2-methoxyethyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-A:2,3-D]pyrimidine-3-carboxamide

CAS 370586-42-8C₂₀H₁₉N₅O₄

N-(2-Furylmethyl)(2-imino-1-methyl-5-oxo(1,6-dihydropyridino[1,2-a]pyridino[2, 3-d]pyrimidin-3-yl))carboxamide

CAS 371922-38-2C₁₈H₁₅N₅O₃

1-Allyl-N-(2-furylmethyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-A:2,3-D]pyrimidine-3-carboxamide

CAS 510761-25-8C₂₀H₁₇N₅O₃

N-(Furan-2-ylmethyl)-2-imino-8-methyl-5-oxo-1-(prop-2-en-1-yl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

CAS 683806-70-4C₂₁H₁₉N₅O₃

1-Ethyl-N-(2-furylmethyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-A:2,3-D]pyrimidine-3-carboxamide

CAS 488839-72-1C₁₉H₁₇N₅O₃

1-Ethyl-N-(2-furylmethyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-A:2,3-D]pyrimidine-3-carboxamide

CAS 487022-36-6C₂₀H₁₉N₅O₃

N-(2-Furylmethyl)-2-imino-5-oxo-1-propyl-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide

CAS 371129-69-0C₂₀H₁₉N₅O₃

N-(2-Furylmethyl)-2-imino-10-methyl-5-oxo-1-propyl-1,5-dihydro-2H-dipyrido[1,2-A:2,3-D]pyrimidine-3-carboxamide

CAS 488110-73-2C₂₁H₂₁N₅O₃

N-(Furan-2-ylmethyl)-2-imino-8-methyl-5-oxo-1-propyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

CAS 842963-01-3C₂₁H₂₁N₅O₃

N-(2-Furylmethyl)-2-imino-1-isopropyl-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

CAS 692264-72-5C₂₁H₂₁N₅O₃

N-(Furan-2-ylmethyl)-2-imino-8-methyl-5-oxo-1-(propan-2-yl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

CAS 799251-09-5C₂₁H₂₁N₅O₃

N-(2-Furylmethyl)-2-imino-1-(2-methoxyethyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-A:2,3-D]pyrimidine-3-carboxamide

CAS 510762-40-0C₂₁H₂₁N₅O₄

N-(Furan-2-ylmethyl)-1-(3-hydroxypropyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

CAS 692280-83-4C₂₁H₂₁N₅O₄

1-Butyl-N-(2-furylmethyl)-2-imino-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido(1,2-A:2,3-D)pyrimidine-3-carboxamide

CAS 510762-24-0C₂₂H₂₃N₅O₃

$N-[(Furan-2-yl)methyl]-6-imino-7-(2-methoxyethyl)-13-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C21H21N5O4, CAS 842963-51-3$

N-[(Furan-2-yl)methyl]-6-imino-7-(2-methoxyethyl)-13-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide

CAS 842963-51-3C₂₁H₂₁N₅O₄

N-(2-Furylmethyl)-2-imino-1-(3-methoxypropyl)-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2,3-d]pyrimidine-3-carboxamide

CAS 510762-70-6C₂₁H₂₁N₅O₄

$N-[(Furan-2-yl)methyl]-6-imino-7-(3-methoxypropyl)-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C22H23N5O4, CAS 510762-72-8$

N-[(Furan-2-yl)methyl]-6-imino-7-(3-methoxypropyl)-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide

CAS 510762-72-8C₂₂H₂₃N₅O₄

$N-[(Furan-2-yl)methyl]-6-imino-7-(3-methoxypropyl)-13-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C22H23N5O4, CAS 842964-16-3$

N-[(Furan-2-yl)methyl]-6-imino-7-(3-methoxypropyl)-13-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide

CAS 842964-16-3C₂₂H₂₃N₅O₄

1-(3-Ethoxypropyl)-N-(furan-2-ylmethyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

CAS 797814-79-0C₂₂H₂₃N₅O₄

$7-(3-Ethoxypropyl)-N-[(furan-2-yl)methyl]-6-imino-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C23H25N5O4, CAS 797814-80-3$

7-(3-Ethoxypropyl)-N-[(furan-2-yl)methyl]-6-imino-11-methyl-2-oxo-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide

CAS 797814-80-3C₂₃H₂₅N₅O₄

1-sec-Butyl-N-(2-furylmethyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-A:2,3-D]pyrimidine-3-carboxamide

CAS 510733-41-2C₂₁H₂₁N₅O₃

1-(Butan-2-yl)-N-(furan-2-ylmethyl)-2-imino-8-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

CAS 879955-93-8C₂₂H₂₃N₅O₃

N-(Furan-2-ylmethyl)-1-(3-hydroxypropyl)-2-imino-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

CAS 685122-02-5C₂₀H₁₉N₅O₄

$N-[(Furan-2-yl)methyl]-6-imino-2-oxo-7-(propan-2-yl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide chemical structure, C20H19N5O3, CAS 618080-97-0$

N-[(Furan-2-yl)methyl]-6-imino-2-oxo-7-(propan-2-yl)-1,7,9-triazatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide

CAS 618080-97-0C₂₀H₁₉N₅O₃

Ring system with 4 rings and 25 atoms

Chemicals with this scaffold

Related scaffolds