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Murcko scaffold

Ring system with 4 rings and 21 atoms

23 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 21
Chemicals: 23
With full pages: 13

Scaffold SMILES

O=C(c1ccccc1)c1ccc2c3ccccc3ccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(c1ccccc1)c1ccc2c3ccccc3ccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

Ethyl 2-amino-3-benzoylpyrrolo[2,1-a]isoquinoline-1-carboxylate chemical structure, C22H18N2O3, CAS 73813-21-5

Ethyl 2-amino-3-benzoylpyrrolo[2,1-a]isoquinoline-1-carboxylate

CAS 73813-21-5C₂₂H₁₈N₂O₃

3-(3,4-Dimethoxybenzoyl)pyrrolo[2,1-a]isoquinoline-1-carbonitrile chemical structure, C22H16N2O3, CAS 618070-11-4

3-(3,4-Dimethoxybenzoyl)pyrrolo[2,1-a]isoquinoline-1-carbonitrile

CAS 618070-11-4C₂₂H₁₆N₂O₃

[1,2-Bis(propylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl](4-methoxyphenyl)methanone chemical structure, C26H27NO6S2, CAS 313377-23-0

[1,2-Bis(propylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl](4-methoxyphenyl)methanone

CAS 313377-23-0C₂₆H₂₇NO₆S₂

[1,2-Bis(ethylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl]-(4-chlorophenyl)methanone chemical structure, C23H20ClNO5S2, CAS 296245-29-9

[1,2-Bis(ethylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl]-(4-chlorophenyl)methanone

CAS 296245-29-9C₂₃H₂₀ClNO₅S₂

[1,2-Bis(propylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl]-(4-methylphenyl)methanone chemical structure, C26H27NO5S2, CAS 327041-78-1

[1,2-Bis(propylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl]-(4-methylphenyl)methanone

CAS 327041-78-1C₂₆H₂₇NO₅S₂

[1,2-Bis(propylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl](4-bromophenyl)methanone chemical structure, C25H24BrNO5S2, CAS 313377-22-9

[1,2-Bis(propylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl](4-bromophenyl)methanone

CAS 313377-22-9C₂₅H₂₄BrNO₅S₂

Diethyl 3-(4-bromobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C25H20BrNO5, CAS 618070-09-0

Diethyl 3-(4-bromobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 618070-09-0C₂₅H₂₀BrNO₅

[1,2-Bis(propylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl](2,4-dimethylphenyl)methanone chemical structure, C27H29NO5S2, CAS 5309-99-9

[1,2-Bis(propylsulfonyl)pyrrolo[2,1-a]isoquinolin-3-yl](2,4-dimethylphenyl)methanone

CAS 5309-99-9C₂₇H₂₉NO₅S₂

Dimethyl 3-(2-chlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C23H16ClNO5, CAS 618443-45-1

Dimethyl 3-(2-chlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 618443-45-1C₂₃H₁₆ClNO₅

Ethyl 3-(3-nitrobenzoyl)pyrrolo[2,1-a]isoquinoline-1-carboxylate chemical structure, C22H16N2O5, CAS 883805-53-6

Ethyl 3-(3-nitrobenzoyl)pyrrolo[2,1-a]isoquinoline-1-carboxylate

CAS 883805-53-6C₂₂H₁₆N₂O₅

Agn-PC-0N8faf chemical structure, C21H15NO2, CAS 189024-20-2

CAS 189024-20-2C₂₁H₁₅NO₂

3-Benzoyl-1-methylpyrrolo[2,1-A]isoquinolin-2-yl acetate chemical structure, C22H17NO3, CAS 90069-61-7

3-Benzoyl-1-methylpyrrolo[2,1-A]isoquinolin-2-yl acetate

CAS 90069-61-7C₂₂H₁₇NO₃

Diisopropyl 3-benzoylpyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C27H25NO5, CAS 853317-71-2

Diisopropyl 3-benzoylpyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853317-71-2C₂₇H₂₅NO₅

Diisopropyl 3-(4-chlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C27H24ClNO5, CAS 853319-31-0

Diisopropyl 3-(4-chlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853319-31-0C₂₇H₂₄ClNO₅

Diisopropyl 3-(4-methylbenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C28H27NO5, CAS 853319-33-2

Diisopropyl 3-(4-methylbenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853319-33-2C₂₈H₂₇NO₅

Diisopropyl 3-(4-bromobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C27H24BrNO5, CAS 853319-35-4

Diisopropyl 3-(4-bromobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853319-35-4C₂₇H₂₄BrNO₅

Diisopropyl 3-(4-fluorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C27H24FNO5, CAS 853330-54-8

Diisopropyl 3-(4-fluorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853330-54-8C₂₇H₂₄FNO₅

Diisopropyl 3-(3-nitrobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C27H24N2O7, CAS 853330-57-1

Diisopropyl 3-(3-nitrobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853330-57-1C₂₇H₂₄N₂O₇

Diisopropyl 3-(4-nitrobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C27H24N2O7, CAS 853330-60-6

Diisopropyl 3-(4-nitrobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853330-60-6C₂₇H₂₄N₂O₇

Diethyl 3-(2,4-dichlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C25H19Cl2NO5, CAS 853333-99-0

Diethyl 3-(2,4-dichlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853333-99-0C₂₅H₁₉Cl₂NO₅

Dimethyl 3-(2,4-dichlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C23H15Cl2NO5, CAS 853334-36-8

Dimethyl 3-(2,4-dichlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853334-36-8C₂₃H₁₅Cl₂NO₅

Diisopropyl 3-(2,4-dichlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate chemical structure, C27H23Cl2NO5, CAS 853334-37-9

Diisopropyl 3-(2,4-dichlorobenzoyl)pyrrolo(2,1-A)isoquinoline-1,2-dicarboxylate

CAS 853334-37-9C₂₇H₂₃Cl₂NO₅

3-[Hydroxy(phenyl)methylidene]-1-methylpyrrolo[2,1-a]isoquinolin-2(3H)-one chemical structure, C20H15NO2, CAS 90069-64-0

3-[Hydroxy(phenyl)methylidene]-1-methylpyrrolo[2,1-a]isoquinolin-2(3H)-one

CAS 90069-64-0C₂₀H₁₅NO₂