Murcko scaffold
N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-phenyloxamide scaffold
29 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 27
- Chemicals
- 29
- With full pages
- 3
Scaffold SMILES
O=C(Nc1ccccc1)C(=O)Nc1ccc2c(c1)N(C(=O)C1CC1)CCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 29 of 29 chemicals
![N-(4-Chlorophenyl)-N'-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide chemical structure, C21H20ClN3O3, CAS 898413-43-9](/s/ZFUCEDZWFQRCJX-UHFFFAOYSA-N.svg)
N-(4-Chlorophenyl)-N'-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide
CAS 898413-43-9C21H20ClN3O3
![N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(4-methylphenyl)oxamide chemical structure, C22H23N3O3, CAS 898413-45-1](/s/DDNITQGZCWGNGJ-UHFFFAOYSA-N.svg)
N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(4-methylphenyl)oxamide
CAS 898413-45-1C22H23N3O3
![N-(3-Chlorophenyl)-N'-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide chemical structure, C21H20ClN3O3, CAS 898413-47-3](/s/WCDIALPHRAFPMA-UHFFFAOYSA-N.svg)
N-(3-Chlorophenyl)-N'-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide
CAS 898413-47-3C21H20ClN3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(3-methylphenyl)oxamide chemical structure, C22H23N3O3, CAS 898413-49-5](/s/JAQJLVOYJYYBOO-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(3-methylphenyl)oxamide
CAS 898413-49-5C22H23N3O3
![N'-(2-Cyanophenyl)-N-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide chemical structure, C22H20N4O3, CAS 898447-43-3](/s/GOFNGDHOBXNYIS-UHFFFAOYSA-N.svg)
N'-(2-Cyanophenyl)-N-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide
CAS 898447-43-3C22H20N4O3
![N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(4-fluorophenyl)oxamide chemical structure, C21H20FN3O3, CAS 898429-47-5](/s/ZKYUXBGVZFIWGF-UHFFFAOYSA-N.svg)
N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(4-fluorophenyl)oxamide
CAS 898429-47-5C21H20FN3O3
![N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(4-ethylphenyl)oxamide chemical structure, C23H25N3O3, CAS 898413-50-8](/s/QISMKEDXQMBIQR-UHFFFAOYSA-N.svg)
N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(4-ethylphenyl)oxamide
CAS 898413-50-8C23H25N3O3
![N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-phenyloxamide chemical structure, C21H21N3O3, CAS 898447-45-5](/s/CHRBPKVRVHTJJT-UHFFFAOYSA-N.svg)
N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-phenyloxamide
CAS 898447-45-5C21H21N3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,3-dimethylphenyl)oxamide chemical structure, C23H25N3O3, CAS 898429-48-6](/s/LVMIFBYEEUHBRY-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,3-dimethylphenyl)oxamide
CAS 898429-48-6C23H25N3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,6-dimethylphenyl)oxamide chemical structure, C23H25N3O3, CAS 898413-52-0](/s/CVDZSRYFGDSASJ-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,6-dimethylphenyl)oxamide
CAS 898413-52-0C23H25N3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-methoxyphenyl)oxamide chemical structure, C22H23N3O4, CAS 898447-47-7](/s/ATBQHIPXQBTWTF-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-methoxyphenyl)oxamide
CAS 898447-47-7C22H23N3O4
N'-(2-Chlorophenyl)-N-(1-cyclopropanecarbonyl-1,2,3,4-tetrahydroquinolin-7-yl)ethanediamide
CAS 903261-26-7C21H20ClN3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-methylphenyl)oxamide chemical structure, C22H23N3O3, CAS 898429-50-0](/s/ZIVUGDZZHSLWCD-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-methylphenyl)oxamide
CAS 898429-50-0C22H23N3O3
![N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(3,4-dimethylphenyl)oxamide chemical structure, C23H25N3O3, CAS 898413-54-2](/s/NDMDTNKSIKJACU-UHFFFAOYSA-N.svg)
N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(3,4-dimethylphenyl)oxamide
CAS 898413-54-2C23H25N3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,4-dimethylphenyl)oxamide chemical structure, C23H25N3O3, CAS 898429-51-1](/s/PUDVDXBBPRYTLW-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,4-dimethylphenyl)oxamide
CAS 898429-51-1C23H25N3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,5-dimethylphenyl)oxamide chemical structure, C23H25N3O3, CAS 898447-49-9](/s/PSPYSLGSAZVTNF-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,5-dimethylphenyl)oxamide
CAS 898447-49-9C23H25N3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-methoxy-5-methylphenyl)oxamide chemical structure, C23H25N3O4, CAS 898413-56-4](/s/YGUFPYUDBNCIHP-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-methoxy-5-methylphenyl)oxamide
CAS 898413-56-4C23H25N3O4
![N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(4-ethoxyphenyl)oxamide chemical structure, C23H25N3O4, CAS 898429-52-2](/s/MCVXMRYCDPPQLZ-UHFFFAOYSA-N.svg)
N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(4-ethoxyphenyl)oxamide
CAS 898429-52-2C23H25N3O4
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,5-difluorophenyl)oxamide chemical structure, C21H19F2N3O3, CAS 898413-58-6](/s/OLRDMJHDGSNNQL-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2,5-difluorophenyl)oxamide
CAS 898413-58-6C21H19F2N3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(3-fluoro-4-methylphenyl)oxamide chemical structure, C22H22FN3O3, CAS 898429-54-4](/s/KBYNGTLAGMFJBL-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(3-fluoro-4-methylphenyl)oxamide
CAS 898429-54-4C22H22FN3O3
![N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-ethylphenyl)oxamide chemical structure, C23H25N3O3, CAS 898447-52-4](/s/GBZWVSOCHVMYOO-UHFFFAOYSA-N.svg)
N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-ethylphenyl)oxamide
CAS 898447-52-4C23H25N3O3
Methyl 4-(2-((1-(cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinolin-7-yl)amino)-2-oxoacetamido)benzoate
CAS 898429-55-5C23H23N3O5
![N'-(3-Chloro-2-methylphenyl)-N-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide chemical structure, C22H22ClN3O3, CAS 898447-54-6](/s/MJTGGGOJEZXRBD-UHFFFAOYSA-N.svg)
N'-(3-Chloro-2-methylphenyl)-N-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide
CAS 898447-54-6C22H22ClN3O3
N1-(1-(cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinolin-7-yl)-N2-mesityloxalamide
CAS 903312-69-6C24H27N3O3
- N-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N'-(2-ethoxyphenyl)oxamide898413-61-1C23H25N3O4
- N'-(3-Chloro-4-methylphenyl)-N-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide898447-56-8C22H22ClN3O3
- N'-(5-Chloro-2-methylphenyl)-N-[1-(cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]oxamide898429-57-7C22H22ClN3O3
- N'-[1-(Cyclopropanecarbonyl)-3,4-dihydro-2H-quinolin-7-yl]-N-(3-nitrophenyl)oxamide898413-62-2C21H20N4O5
- N1-(3-acetamidophenyl)-N2-(1-(cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxalamide898447-58-0C23H24N4O4