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Murcko scaffold

Ring system with 7 rings and 43 atoms

6 chemicals on CompoundList share this ring system.

Rings
7
Scaffold atoms
43
Chemicals
6
With full pages
3
Scaffold SMILES

O=C(Nc1ncnc2c1ncn2C1CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CCO1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ncnc2c1ncn2C1CN(C(c2ccccc2)(c2ccccc2)c2ccccc2)CCO1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N6-Benzoyl-N9-(6-hydroxymethyl-4-triphenylmethylmorpholin-2-yl) Adenine chemical structure, C36H32N6O3, CAS 956139-16-5
N6-Benzoyl-N9-(6-hydroxymethyl-4-triphenylmethylmorpholin-2-yl) Adenine
CAS 956139-16-5C36H32N6O3
(6-(6-Benzamido-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate chemical structure, C38H37ClN7O4P, CAS 956139-18-7
(6-(6-Benzamido-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
CAS 956139-18-7C38H37ClN7O4P
N-(9-(6-(Hydroxymethyl)-4-tritylmorpholin-2-yl)-9H-purin-6-yl)benzamide chemical structure, C36H32N6O3, CAS 722458-02-8
N-(9-(6-(Hydroxymethyl)-4-tritylmorpholin-2-yl)-9H-purin-6-yl)benzamide
CAS 722458-02-8C36H32N6O3
Phosphoramidochloridic acid, N,N-dimethyl-[6-[6-(benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester chemical structure, C38H37ClN7O4P, CAS 1155373-30-0
Phosphoramidochloridic acid, N,N-dimethyl-[6-[6-(benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester
CAS 1155373-30-0C38H37ClN7O4P
(2R-Cis)-N-[9-[6-(Hydroxymethyl)-4-[(4-methoxyphenyl)diphenylmethyl]-2-morpholinyl]-9H-purin-6-yl]benzamide chemical structure, C37H34N6O4, CAS 139290-79-2
(2R-Cis)-N-[9-[6-(Hydroxymethyl)-4-[(4-methoxyphenyl)diphenylmethyl]-2-morpholinyl]-9H-purin-6-yl]benzamide
CAS 139290-79-2C37H34N6O4
N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite chemical structure, C45H49N8O4P, CAS 2434795-08-9
N-Trityl-N6-benzoyl-morpholino-A-5'-O-phosphoramidite
CAS 2434795-08-9C45H49N8O4P