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Murcko scaffold

N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-2-phenoxyacetamide scaffold

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
30
Chemicals
8
With full pages
4
Scaffold SMILES

O=C(COc1ccccc1)NCC(c1ccco1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-2-phenoxyacetamide page
Murcko scaffold O=C(COc1ccccc1)NCC(c1ccco1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-2-phenoxyacetamide chemical structure, C24H27N3O3, CAS 887215-52-3
N-[2-(Furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]-2-phenoxyacetamide
CAS 887215-52-3C24H27N3O3
2-(4-Chlorophenoxy)-N-[2-(furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]acetamide chemical structure, C24H26ClN3O3, CAS 887215-57-8
2-(4-Chlorophenoxy)-N-[2-(furan-2-yl)-2-(4-phenylpiperazin-1-yl)ethyl]acetamide
CAS 887215-57-8C24H26ClN3O3
N-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-2-phenoxyacetamide chemical structure, C24H26FN3O3, CAS 877632-19-4
N-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-2-phenoxyacetamide
CAS 877632-19-4C24H26FN3O3
2-(4-Chlorophenoxy)-N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)acetamide chemical structure, C24H25ClFN3O3, CAS 887218-49-7
2-(4-Chlorophenoxy)-N-(2-(4-(4-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)acetamide
CAS 887218-49-7C24H25ClFN3O3
N-(2-(4-(2-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-2-phenoxyacetamide chemical structure, C24H26FN3O3, CAS 877632-93-4
N-(2-(4-(2-Fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)-2-phenoxyacetamide
CAS 877632-93-4C24H26FN3O3
2-(4-Chlorophenoxy)-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)acetamide chemical structure, C24H25ClFN3O3, CAS 887220-15-7
2-(4-Chlorophenoxy)-N-(2-(4-(2-fluorophenyl)piperazin-1-yl)-2-(furan-2-yl)ethyl)acetamide
CAS 887220-15-7C24H25ClFN3O3
N-[2-(Furan-2-yl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]-2-phenoxyacetamide chemical structure, C25H29N3O4, CAS 877633-76-6
N-[2-(Furan-2-yl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]-2-phenoxyacetamide
CAS 877633-76-6C25H29N3O4
2-(4-Chlorophenoxy)-N-[2-(furan-2-yl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]acetamide chemical structure, C25H28ClN3O4, CAS 887221-52-5
2-(4-Chlorophenoxy)-N-[2-(furan-2-yl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]acetamide
CAS 887221-52-5C25H28ClN3O4