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Murcko scaffold

1,2,3,4-Tetrahydropyrazino[1,2-a]benzimidazole scaffold

25 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
25
With full pages
4
Scaffold SMILES

c1ccc2c(c1)nc1n2CCNC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,3,4-Tetrahydropyrazino[1,2-a]benzimidazole page
Murcko scaffold c1ccc2c(c1)nc1n2CCNC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

1,2,3,4-Tetrahydropyrazino[1,2-a]benzimidazole chemical structure, C10H11N3, CAS 4744-53-0
1,2,3,4-Tetrahydropyrazino[1,2-a]benzimidazole
CAS 4744-53-0C10H11N3
N-[2-(2-Methoxyethyl)-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazol-8-yl]methanesulfonamide chemical structure, C14H20N4O3S, CAS 902048-30-0
N-[2-(2-Methoxyethyl)-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazol-8-yl]methanesulfonamide
CAS 902048-30-0C14H20N4O3S
N-[2-(2-Methoxyethyl)-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazol-8-yl]acetamide chemical structure, C15H20N4O2, CAS 727685-04-3
N-[2-(2-Methoxyethyl)-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazol-8-yl]acetamide
CAS 727685-04-3C15H20N4O2
1,2,3,4-Tetrahydropyrazino[1,2-a]benzimidazole-7,8-diol chemical structure, C10H11N3O2, CAS 790162-01-5
1,2,3,4-Tetrahydropyrazino[1,2-a]benzimidazole-7,8-diol
CAS 790162-01-5C10H11N3O2
N-(2-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl)acetamide chemical structure, C13H16N4O, CAS 951963-41-0
N-(2-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl)acetamide
CAS 951963-41-0C13H16N4O
N-Ethyl-2-(1-hydroxy-2-methylpropan-2-yl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-8-carboxamide chemical structure, C17H24N4O2, CAS 1089340-71-5
N-Ethyl-2-(1-hydroxy-2-methylpropan-2-yl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-8-carboxamide
CAS 1089340-71-5C17H24N4O2
2-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole chemical structure, C11H13N3, CAS 115213-55-3
2-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole
CAS 115213-55-3C11H13N3
2-Ethyl-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazole chemical structure, C12H15N3, CAS 51052-12-1
2-Ethyl-3,4-dihydro-1H-pyrazino[1,2-a]benzimidazole
CAS 51052-12-1C12H15N3
2-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-amine chemical structure, C11H14N4, CAS 945912-43-6
2-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-amine
CAS 945912-43-6C11H14N4
(1S)-1-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole chemical structure, C11H13N3, CAS 135875-08-0
(1S)-1-Methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole
CAS 135875-08-0C11H13N3
N-(2-Butyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl)butanamide chemical structure, C18H26N4O, CAS 1031628-35-9
N-(2-Butyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl)butanamide
CAS 1031628-35-9C18H26N4O
2-(2-Methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-amine chemical structure, C13H18N4O, CAS 1322605-16-2
2-(2-Methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-amine
CAS 1322605-16-2C13H18N4O
2-(2-Methylpropyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-amine chemical structure, C14H20N4, CAS 1322604-61-4
2-(2-Methylpropyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-amine
CAS 1322604-61-4C14H20N4
2-(Propan-2-yl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-amine chemical structure, C13H18N4, CAS 1322604-89-6
2-(Propan-2-yl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-amine
CAS 1322604-89-6C13H18N4
1,2,3,4-Tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine-8-carboxylic acid chemical structure, C11H11N3O2, CAS 1354411-11-2
1,2,3,4-Tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine-8-carboxylic acid
CAS 1354411-11-2C11H11N3O2
8-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine chemical structure, C10H10BrN3, CAS 1897613-72-7
8-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine
CAS 1897613-72-7C10H10BrN3
7-Fluoro-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine chemical structure, C10H10FN3, CAS 1288979-04-3
7-Fluoro-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine
CAS 1288979-04-3C10H10FN3
7-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine chemical structure, C10H10BrN3, CAS 1781900-31-9
7-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine
CAS 1781900-31-9C10H10BrN3
2-Methyl-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine-8-carboxylic acid chemical structure, C12H13N3O2, CAS 1708159-81-2
2-Methyl-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine-8-carboxylic acid
CAS 1708159-81-2C12H13N3O2
6-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine chemical structure, C10H10BrN3, CAS 1783932-03-5
6-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine
CAS 1783932-03-5C10H10BrN3
9-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine chemical structure, C10H10BrN3, CAS 1780512-80-2
9-Bromo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine
CAS 1780512-80-2C10H10BrN3
(R)-Methyl 1-isopropyl-7-(methylsulfonyl)-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine-8-carboxylate chemical structure, C16H21N3O4S, CAS 1456693-55-2
(R)-Methyl 1-isopropyl-7-(methylsulfonyl)-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine-8-carboxylate
CAS 1456693-55-2C16H21N3O4S
Methyl 2-ethyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-8-carboxylate chemical structure, C14H17N3O2, CAS 1779124-80-9
Methyl 2-ethyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-8-carboxylate
CAS 1779124-80-9C14H17N3O2
Methyl 1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine-8-carboxylate chemical structure, C12H13N3O2, CAS 1955519-86-4
Methyl 1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine-8-carboxylate
CAS 1955519-86-4C12H13N3O2