CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 33 atoms

4 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
33
Chemicals
4
With full pages
4
Scaffold SMILES

O=C1C(=O)N(c2nccs2)C(c2ccccc2)C1=Cc1ccc(OCc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=O)N(c2nccs2)C(c2ccccc2)C1=Cc1ccc(OCc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Ethyl 2-[3-[4-(benzyloxy)-2-methylbenzoyl]-4-hydroxy-2-(4-methylphenyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C33H30N2O6S, CAS 488723-09-7
Ethyl 2-[3-[4-(benzyloxy)-2-methylbenzoyl]-4-hydroxy-2-(4-methylphenyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
CAS 488723-09-7C33H30N2O6S
Ethyl 2-(3-(4-(benzyloxy)-2-methylbenzoyl)-2-(4-chlorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C32H27ClN2O6S, CAS 488102-99-4
Ethyl 2-(3-(4-(benzyloxy)-2-methylbenzoyl)-2-(4-chlorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methyl-1,3-thiazole-5-carboxylate
CAS 488102-99-4C32H27ClN2O6S
Ethyl 2-{3-[4-(benzyloxy)-2-methylbenzoyl]-4-hydroxy-5-oxo-2-phenyl-2,5-dihydro-1H-pyrrol-1-YL}-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C32H28N2O6S, CAS 500276-74-4
Ethyl 2-{3-[4-(benzyloxy)-2-methylbenzoyl]-4-hydroxy-5-oxo-2-phenyl-2,5-dihydro-1H-pyrrol-1-YL}-4-methyl-1,3-thiazole-5-carboxylate
CAS 500276-74-4C32H28N2O6S
Ethyl 2-[3-[4-(benzyloxy)-2-methylbenzoyl]-2-(4-ethylphenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C34H32N2O6S, CAS 488803-76-5
Ethyl 2-[3-[4-(benzyloxy)-2-methylbenzoyl]-2-(4-ethylphenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
CAS 488803-76-5C34H32N2O6S