Murcko scaffold
Ring system with 6 rings and 34 atoms
29 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 34
- Chemicals
- 29
- With full pages
- 5
Scaffold SMILES
O=c1c(=Cc2cn(-c3ccccc3)nc2-c2ccccc2)sc2n1C(c1ccccc1)C=CN=2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 29 of 29 chemicals
![Ethyl 5-(4-acetyloxyphenyl)-2-[(1,3-diphenylpyrazol-4-yl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C34H28N4O5S, CAS 5730-41-6](/s/VXZDVZZUUMHTCB-UHFFFAOYSA-N.svg)
Ethyl 5-(4-acetyloxyphenyl)-2-[(1,3-diphenylpyrazol-4-yl)methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 5730-41-6C34H28N4O5S
![Methyl 5-(4-tert-butylphenyl)-2-[[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C35H31FN4O3S, CAS 312313-97-6](/s/WTLNKKSJOFMOKJ-UHFFFAOYSA-N.svg)
Methyl 5-(4-tert-butylphenyl)-2-[[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]methylidene]-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 312313-97-6C35H31FN4O3S
![Ethyl 2-[[3-(4-chlorophenyl)-1-phenylpyrazol-4-yl]methylidene]-5-(4-methoxycarbonylphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C34H27ClN4O5S, CAS 6998-03-4](/s/ZTEKNRVUSZVQPI-UHFFFAOYSA-N.svg)
Ethyl 2-[[3-(4-chlorophenyl)-1-phenylpyrazol-4-yl]methylidene]-5-(4-methoxycarbonylphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-03-4C34H27ClN4O5S
![Prop-2-enyl 2-[[3-(4-bromophenyl)-1-phenylpyrazol-4-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C34H27BrN4O3S2, CAS 6998-07-8](/s/SRIZVALVXASIPO-UHFFFAOYSA-N.svg)
Prop-2-enyl 2-[[3-(4-bromophenyl)-1-phenylpyrazol-4-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-07-8C34H27BrN4O3S2
![Ethyl 5-(4-methoxycarbonylphenyl)-7-methyl-3-oxo-2-[[1-phenyl-3-(4-prop-2-enoxyphenyl)pyrazol-4-yl]methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C37H32N4O6S, CAS 6998-23-8](/s/WNQVPCFMGHCUJZ-UHFFFAOYSA-N.svg)
Ethyl 5-(4-methoxycarbonylphenyl)-7-methyl-3-oxo-2-[[1-phenyl-3-(4-prop-2-enoxyphenyl)pyrazol-4-yl]methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-23-8C37H32N4O6S
![2-Methylpropyl 7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-2-[[1-phenyl-3-(4-propan-2-yloxyphenyl)pyrazol-4-yl]methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C38H38N4O4S2, CAS 6998-24-9](/s/TWNQKKYORRSRLZ-UHFFFAOYSA-N.svg)
2-Methylpropyl 7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-2-[[1-phenyl-3-(4-propan-2-yloxyphenyl)pyrazol-4-yl]methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-24-9C38H38N4O4S2
![Ethyl 5-[4-(methoxycarbonyl)phenyl]-7-methyl-3-oxo-2-[(1-phenyl-3-{4-[(propan-2-yl)oxy]phenyl}-1H-pyrazol-4-yl)methylidene]-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C37H34N4O6S, CAS 6998-25-0](/s/GFGMQPFCMZJATM-UHFFFAOYSA-N.svg)
Ethyl 5-[4-(methoxycarbonyl)phenyl]-7-methyl-3-oxo-2-[(1-phenyl-3-{4-[(propan-2-yl)oxy]phenyl}-1H-pyrazol-4-yl)methylidene]-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-25-0C37H34N4O6S
![2-Methylpropyl 7-methyl-2-{[3-(3-methyl-4-propoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C39H40N4O4S2, CAS 6998-26-1](/s/IDOFJOLODIIKLJ-UHFFFAOYSA-N.svg)
2-Methylpropyl 7-methyl-2-{[3-(3-methyl-4-propoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-26-1C39H40N4O4S2
![Methyl 2-{[3-(4-ethoxy-3-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C34H29N5O6S2, CAS 6998-14-7](/s/ILSIIWNSWKSZTC-UHFFFAOYSA-N.svg)
Methyl 2-{[3-(4-ethoxy-3-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-14-7C34H29N5O6S2
![2-Methylpropyl 2-[[3-(4-ethoxy-3-nitrophenyl)-1-phenylpyrazol-4-yl]methylidene]-5-(4-methoxycarbonylphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C38H35N5O8S, CAS 6998-15-8](/s/VDSWBIFZRNLOLI-UHFFFAOYSA-N.svg)
2-Methylpropyl 2-[[3-(4-ethoxy-3-nitrophenyl)-1-phenylpyrazol-4-yl]methylidene]-5-(4-methoxycarbonylphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-15-8C38H35N5O8S
![Propan-2-yl 5-(4-methoxycarbonylphenyl)-7-methyl-3-oxo-2-[[1-phenyl-3-(4-propoxyphenyl)pyrazol-4-yl]methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C38H36N4O6S, CAS 6998-19-2](/s/PSXZNGYCWNNJRC-UHFFFAOYSA-N.svg)
Propan-2-yl 5-(4-methoxycarbonylphenyl)-7-methyl-3-oxo-2-[[1-phenyl-3-(4-propoxyphenyl)pyrazol-4-yl]methylidene]-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-19-2C38H36N4O6S
![Propan-2-yl 7-methyl-2-[(3-{3-methyl-4-[(propan-2-yl)oxy]phenyl}-1-phenyl-1H-pyrazol-4-yl)methylidene]-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C38H38N4O4S2, CAS 6998-28-3](/s/ZWDYJPZOFJWUFV-UHFFFAOYSA-N.svg)
Propan-2-yl 7-methyl-2-[(3-{3-methyl-4-[(propan-2-yl)oxy]phenyl}-1-phenyl-1H-pyrazol-4-yl)methylidene]-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-28-3C38H38N4O4S2
![Prop-2-en-1-yl 7-methyl-2-({3-[3-methyl-4-(3-methylbutoxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C40H40N4O4S2, CAS 6998-29-4](/s/BQTVMTRMVOCWFY-UHFFFAOYSA-N.svg)
Prop-2-en-1-yl 7-methyl-2-({3-[3-methyl-4-(3-methylbutoxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-29-4C40H40N4O4S2
![2-Methylpropyl 2-{[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C35H31FN4O3S2, CAS 6998-04-5](/s/BYGDQIVLERUMBN-UHFFFAOYSA-N.svg)
2-Methylpropyl 2-{[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-7-methyl-5-[4-(methylsulfanyl)phenyl]-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-04-5C35H31FN4O3S2
![2-Methylpropyl 5-(4-methoxycarbonylphenyl)-7-methyl-2-[[3-[4-(3-methylbutoxy)phenyl]-1-phenylpyrazol-4-yl]methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C41H42N4O6S, CAS 6998-17-0](/s/UVMMNISTPSPBDR-UHFFFAOYSA-N.svg)
2-Methylpropyl 5-(4-methoxycarbonylphenyl)-7-methyl-2-[[3-[4-(3-methylbutoxy)phenyl]-1-phenylpyrazol-4-yl]methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-17-0C41H42N4O6S
![Prop-2-enyl 2-[[3-(4-methoxyphenyl)-1-phenylpyrazol-4-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C35H30N4O4S2, CAS 6998-09-0](/s/VHSOAIZUDITDPB-UHFFFAOYSA-N.svg)
Prop-2-enyl 2-[[3-(4-methoxyphenyl)-1-phenylpyrazol-4-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-09-0C35H30N4O4S2
![Prop-2-enyl 2-[[3-(3-bromo-4-methoxyphenyl)-1-phenylpyrazol-4-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C35H29BrN4O4S2, CAS 6998-11-4](/s/BYEPQAKTTYEOHJ-UHFFFAOYSA-N.svg)
Prop-2-enyl 2-[[3-(3-bromo-4-methoxyphenyl)-1-phenylpyrazol-4-yl]methylidene]-7-methyl-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 6998-11-4C35H29BrN4O4S2
![Propan-2-yl 7-methyl-2-[[3-(3-methyl-4-prop-2-enoxyphenyl)-1-phenylpyrazol-4-yl]methylidene]-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C38H36N4O4S2](/s/QILUFVJSEAEPCY-UHFFFAOYSA-N.svg)
Propan-2-yl 7-methyl-2-[[3-(3-methyl-4-prop-2-enoxyphenyl)-1-phenylpyrazol-4-yl]methylidene]-5-(4-methylsulfanylphenyl)-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
C38H36N4O4S2
![Ethyl (2Z)-7-methyl-2-[[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C33H28N4O3S, CAS 5874-40-8](/s/KXHWUIDRUPAKKU-DIBXZPPDSA-N.svg)
Ethyl (2Z)-7-methyl-2-[[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 5874-40-8C33H28N4O3S
![Methyl (2Z)-7-methyl-2-[[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C32H26N4O3S, CAS 313361-42-1](/s/DDUAOQKIQXNVSN-ITYLOYPMSA-N.svg)
Methyl (2Z)-7-methyl-2-[[3-(4-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 313361-42-1C32H26N4O3S
![(Z)-Ethyl 2-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)-7-methyl-3-oxo-5-phenyl-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C32H26N4O3S, CAS 356564-21-1](/s/JOHOIZJLVWLIRI-XHPQRKPJSA-N.svg)
(Z)-Ethyl 2-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)-7-methyl-3-oxo-5-phenyl-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 356564-21-1C32H26N4O3S
![(Z)-Ethyl 2-((3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-7-methyl-3-oxo-5-phenyl-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C32H25ClN4O3S, CAS 311810-04-5](/s/ZHSNYKHYCILLFY-ITYLOYPMSA-N.svg)
(Z)-Ethyl 2-((3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-7-methyl-3-oxo-5-phenyl-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 311810-04-5C32H25ClN4O3S
![Methyl (2Z)-2-[(1,3-diphenyl-1H-pyrazol-4-yl)methylidene]-7-methyl-3-oxo-5-phenyl-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate chemical structure, C31H24N4O3S, CAS 313050-17-8](/s/ZUBOGOHXEGCZSV-BWAHOGKJSA-N.svg)
Methyl (2Z)-2-[(1,3-diphenyl-1H-pyrazol-4-yl)methylidene]-7-methyl-3-oxo-5-phenyl-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
CAS 313050-17-8C31H24N4O3S
Ethyl (2Z)-2-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)-7-methyl-5-(4-(methylsu lfanyl)phenyl)-3-oxo-2,3-dihydro-5H-(1,3)thiazolo(3,2-A)pyrimidine-6-car boxylate
CAS 623935-41-1C33H28N4O3S2
- RefChem:592984483276-20-6C34H30N4O4S
- Ethyl (2E)-7-methyl-2-((3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-oxo-5-phenyl-2,3-dihydro-5H-(1,3)thiazolo(3,2-A)pyrimidine-6-carboxyl ate313272-50-3C33H28N4O3S
- Propan-2-yl 4-methyl-8-[[3-(3-methyl-4-prop-2-enoxy-phenyl)-1-phenyl-pyrazol-4-yl]methylidene]-2-(4-methylsulfanylphenyl)-9-oxo-7-thia-1,5-diazabicyclo[4.3.0]nona-3,5-diene-3-carboxylate6998-30-7C38H36N4O4S2
- RefChem:592995624726-70-1C34H30N4O3S
- Ethyl (2E)-5-(4-chlorophenyl)-2-[(1,3-diphenyl-1H-pyrazol-4-yl)methylene]-7-ME thyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-A]pyrimidine-6-carboxylate624726-74-5C32H25ClN4O3S