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Murcko scaffold

N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide scaffold

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
32
Chemicals
10
With full pages
7
Scaffold SMILES

O=C(NCCc1c[nH]c2ccccc12)C(=O)NCC1OCCN1S(=O)(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide page
Murcko scaffold O=C(NCCc1c[nH]c2ccccc12)C(=O)NCC1OCCN1S(=O)(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[2-(1H-Indol-3-yl)ethyl]-N''-[[3-(4-methoxyphenyl)sulfonyl-2-oxazolidinyl]methyl]oxamide chemical structure, C23H26N4O6S, CAS 868981-43-5
N-[2-(1H-Indol-3-yl)ethyl]-N''-[[3-(4-methoxyphenyl)sulfonyl-2-oxazolidinyl]methyl]oxamide
CAS 868981-43-5C23H26N4O6S
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((4-fluorophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C22H23FN4O5S, CAS 868982-39-2
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((4-fluorophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868982-39-2C22H23FN4O5S
N-[2-(1H-Indol-3-yl)ethyl]-N''-[[3-(4-methoxy-3-methylphenyl)sulfonyl-2-oxazolidinyl]methyl]oxamide chemical structure, C24H28N4O6S, CAS 874804-53-2
N-[2-(1H-Indol-3-yl)ethyl]-N''-[[3-(4-methoxy-3-methylphenyl)sulfonyl-2-oxazolidinyl]methyl]oxamide
CAS 874804-53-2C24H28N4O6S
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((4-chlorophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C22H23ClN4O5S, CAS 874805-52-4
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((4-chlorophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 874805-52-4C22H23ClN4O5S
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-(mesitylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C25H30N4O5S, CAS 868982-90-5
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-(mesitylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868982-90-5C25H30N4O5S
N-[2-(1H-Indol-3-yl)ethyl]-N''-[(3-tosyloxazolidin-2-yl)methyl]oxamide chemical structure, C23H26N4O5S, CAS 874806-06-1
N-[2-(1H-Indol-3-yl)ethyl]-N''-[(3-tosyloxazolidin-2-yl)methyl]oxamide
CAS 874806-06-1C23H26N4O5S
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C22H24N4O5S, CAS 868981-76-4
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868981-76-4C22H24N4O5S
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((2,5-difluorophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C22H22F2N4O5S, CAS 868983-70-4
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((2,5-difluorophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868983-70-4C22H22F2N4O5S
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((3,4-dimethoxyphenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C24H28N4O7S, CAS 868983-28-2
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((3,4-dimethoxyphenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868983-28-2C24H28N4O7S
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((4-bromophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C22H23BrN4O5S, CAS 868981-06-0
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((4-bromophenyl)sulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 868981-06-0C22H23BrN4O5S