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Murcko scaffold

4-(Anilinomethyl)-1(2H)-phthalazinone scaffold

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
14
With full pages
7
Scaffold SMILES

O=c1[nH]nc(CNc2ccccc2)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Anilinomethyl)-1(2H)-phthalazinone page
Murcko scaffold O=c1[nH]nc(CNc2ccccc2)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

4-[(2,4-Dichloroanilino)methyl]-1(2H)-phthalazinone chemical structure, C15H11Cl2N3O, CAS 303995-64-4
4-[(2,4-Dichloroanilino)methyl]-1(2H)-phthalazinone
CAS 303995-64-4C15H11Cl2N3O
4-((2,4-Difluoroanilino)methyl)-1(2H)-phthalazinone chemical structure, C15H11F2N3O, CAS 305368-09-6
4-((2,4-Difluoroanilino)methyl)-1(2H)-phthalazinone
CAS 305368-09-6C15H11F2N3O
4-((4-Chloroanilino)methyl)-1(2H)-phthalazinone chemical structure, C15H12ClN3O, CAS 303995-15-5
4-((4-Chloroanilino)methyl)-1(2H)-phthalazinone
CAS 303995-15-5C15H12ClN3O
4-(Anilinomethyl)-1(2H)-phthalazinone chemical structure, C15H13N3O, CAS 303995-47-3
4-(Anilinomethyl)-1(2H)-phthalazinone
CAS 303995-47-3C15H13N3O
4-{[3-(Trifluoromethyl)anilino]methyl}-1(2H)-phthalazinone chemical structure, C16H12F3N3O, CAS 303995-58-6
4-{[3-(Trifluoromethyl)anilino]methyl}-1(2H)-phthalazinone
CAS 303995-58-6C16H12F3N3O
2-{[(4-Oxo-3,4-dihydro-1-phthalazinyl)methyl]amino}benzenecarbonitrile chemical structure, C16H12N4O, CAS 303995-59-7
2-{[(4-Oxo-3,4-dihydro-1-phthalazinyl)methyl]amino}benzenecarbonitrile
CAS 303995-59-7C16H12N4O
4-[(4-Methoxyanilino)methyl]-1(2H)-phthalazinone chemical structure, C16H15N3O2, CAS 303995-62-2
4-[(4-Methoxyanilino)methyl]-1(2H)-phthalazinone
CAS 303995-62-2C16H15N3O2
4-[(Methylanilino)methyl]-1(2H)-phthalazinone chemical structure, C16H15N3O, CAS 303995-67-7
4-[(Methylanilino)methyl]-1(2H)-phthalazinone
CAS 303995-67-7C16H15N3O
N,N-Dimethyl-4-{[(4-oxo-3,4-dihydro-1-phthalazinyl)methyl]amino}benzenesulfonamide chemical structure, C17H18N4O3S, CAS 305368-06-3
N,N-Dimethyl-4-{[(4-oxo-3,4-dihydro-1-phthalazinyl)methyl]amino}benzenesulfonamide
CAS 305368-06-3C17H18N4O3S
4-[(4-Hydroxyanilino)methyl]-1(2H)-phthalazinone chemical structure, C15H13N3O2, CAS 305368-05-2
4-[(4-Hydroxyanilino)methyl]-1(2H)-phthalazinone
CAS 305368-05-2C15H13N3O2
4-{[4-(Trifluoromethoxy)anilino]methyl}-1(2H)-phthalazinone chemical structure, C16H12F3N3O2, CAS 305368-11-0
4-{[4-(Trifluoromethoxy)anilino]methyl}-1(2H)-phthalazinone
CAS 305368-11-0C16H12F3N3O2
4-{[3-(Methylsulfanyl)anilino]methyl}-1(2H)-phthalazinone chemical structure, C16H15N3OS, CAS 305368-08-5
4-{[3-(Methylsulfanyl)anilino]methyl}-1(2H)-phthalazinone
CAS 305368-08-5C16H15N3OS
4-((4-Nitroanilino)methyl)-1(2H)-phthalazinone chemical structure, C15H12N4O3, CAS 305368-07-4
4-((4-Nitroanilino)methyl)-1(2H)-phthalazinone
CAS 305368-07-4C15H12N4O3
4-{[4-(Trifluoromethyl)anilino]methyl}-1(2H)-phthalazinone chemical structure, C16H12F3N3O, CAS 305368-12-1
4-{[4-(Trifluoromethyl)anilino]methyl}-1(2H)-phthalazinone
CAS 305368-12-1C16H12F3N3O