CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 28 atoms

36 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
36
With full pages
11
Scaffold SMILES

C(=Cc1ccccc1)CN1CCN(C(c2ccccc2)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1ccccc1)CN1CCN(C(c2ccccc2)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

1-(Bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propen-1-yl)piperazine chemical structure, C26H26F2N2, CAS 40218-96-0
1-(Bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propen-1-yl)piperazine
CAS 40218-96-0C26H26F2N2
Flunarizine chemical structure, C26H26F2N2, CAS 52468-60-7
Flunarizine
CAS 52468-60-7C26H26F2N2
Cinnarizine chemical structure, C26H28N2, CAS 298-57-7
Cinnarizine
CAS 298-57-7C26H28N2
(E)-1-Benzhydryl-4-cinnamylpiperazine chemical structure, C26H28N2, CAS 750512-44-8
(E)-1-Benzhydryl-4-cinnamylpiperazine
CAS 750512-44-8C26H28N2
(Z)-Flunarizine chemical structure, C26H26F2N2, CAS 693765-11-6
(Z)-Flunarizine
CAS 693765-11-6C26H26F2N2
Flunarizine hydrochloride chemical structure, C26H28Cl2F2N2, CAS 30484-77-6
Flunarizine hydrochloride
CAS 30484-77-6C26H28Cl2F2N2
Clocinizine chemical structure, C26H27ClN2, CAS 298-55-5
Clocinizine
CAS 298-55-5C26H27ClN2
REGID_for_CID_6365505 chemical structure, C26H27ClF2N2, CAS 1164531-52-5
REGID_for_CID_6365505
CAS 1164531-52-5C26H27ClF2N2
Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-(2,3,4-trimethoxyphenyl)-2-propenyl)-, dihydrochloride chemical structure, C29H34Cl2F2N2O3, CAS 104690-85-9
Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-(2,3,4-trimethoxyphenyl)-2-propenyl)-, dihydrochloride
CAS 104690-85-9C29H34Cl2F2N2O3
Piperazine, 1-(diphenylmethyl)-4-(3-(2,3,4-trimethoxyphenyl)-2-propenyl)-, dihydrochloride chemical structure, C29H36Cl2N2O3, CAS 104690-88-2
Piperazine, 1-(diphenylmethyl)-4-(3-(2,3,4-trimethoxyphenyl)-2-propenyl)-, dihydrochloride
CAS 104690-88-2C29H36Cl2N2O3
Cinnarizine clofibrate chemical structure, C36H39ClN2O3, CAS 60763-49-7
Cinnarizine clofibrate
CAS 60763-49-7C36H39ClN2O3
PU 122 chemical structure, C28H32Cl2F2N2O2, CAS 99661-27-5
PU 122
CAS 99661-27-5C28H32Cl2F2N2O2
Trelnarizine chemical structure, C28H30F2N2O2, CAS 123205-52-7
Trelnarizine
CAS 123205-52-7C28H30F2N2O2
1-(Bis(4-fluorophenyl)methyl)-4-(3-(4'-hydroxyphenyl)-2-propenyl)piperazine chemical structure, C26H26F2N2O, CAS 100551-77-7
1-(Bis(4-fluorophenyl)methyl)-4-(3-(4'-hydroxyphenyl)-2-propenyl)piperazine
CAS 100551-77-7C26H26F2N2O
Clocinizine hydrochloride chemical structure, C26H29Cl3N2, CAS 39245-23-3
Clocinizine hydrochloride
CAS 39245-23-3C26H29Cl3N2
Sureptil chemical structure, C43H57N7O5, CAS 79121-49-6
Sureptil
CAS 79121-49-6C43H57N7O5
Cinnarizine, dihydrochloride chemical structure, C26H30Cl2N2, CAS 7002-58-6
Cinnarizine, dihydrochloride
CAS 7002-58-6C26H30Cl2N2
Denoral chemical structure, C58H74Cl4IN5O2, CAS 58653-46-6
Denoral
CAS 58653-46-6C58H74Cl4IN5O2
Descinnamyl-4-cinnamyl cinnarizine chemical structure, C26H28N2O, CAS 185629-15-6
Descinnamyl-4-cinnamyl cinnarizine
CAS 185629-15-6C26H28N2O
Flunarizine impurity B chemical structure, C26H27FN2, CAS 39245-25-5
Flunarizine impurity B
CAS 39245-25-5C26H27FN2
Piperazine, 1-(3-(2,4-dimethoxyphenyl)-2-propenyl)-4-(diphenylmethyl)-, (E)-2-butenedioate (1:1) chemical structure, C32H36N2O6, CAS 104690-93-9
Piperazine, 1-(3-(2,4-dimethoxyphenyl)-2-propenyl)-4-(diphenylmethyl)-, (E)-2-butenedioate (1:1)
CAS 104690-93-9C32H36N2O6
Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-(2,4-dimethoxyphenyl)-2-propenyl)-, (E)-2-butenedioate (1:1) chemical structure, C32H34F2N2O6, CAS 104690-91-7
Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-(2,4-dimethoxyphenyl)-2-propenyl)-, (E)-2-butenedioate (1:1)
CAS 104690-91-7C32H34F2N2O6
(Z)-1-(Bis(4-fluorophenyl)methyl)-4-(cinnamyl)piperazine hydrochloride chemical structure, C26H27ClF2N2, CAS 53114-47-9
(Z)-1-(Bis(4-fluorophenyl)methyl)-4-(cinnamyl)piperazine hydrochloride
CAS 53114-47-9C26H27ClF2N2
Cinnarizine hydrochloride chemical structure, C26H29ClN2, CAS 25332-14-3
Cinnarizine hydrochloride
CAS 25332-14-3C26H29ClN2