Murcko scaffold

Quadricyclane scaffold

18 chemicals on CompoundList share this ring system.

Rings: 5
Scaffold atoms: 7
Chemicals: 18
With full pages: 2

Scaffold SMILES

C1C2C3C2C2C1C32

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the Quadricyclane page

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Quadricyclane

CAS 278-06-8C₇H₈

1,5-Dicarbomethoxy quadricyclane

CAS 714-53-4C₁₁H₁₂O₄

5-((Methylamino)carbonyl)tetracyclo(3.2.0(2,7).0(4,6))heptane-1-carboxylic acid

CAS 90632-73-8C₁₀H₁₁NO₃

3-Tetracyclo[3.2.0.02,7.04,6]heptanyl acetate

CAS 35825-94-6C₉H₁₀O₂

1-(1-Tetracyclo[3.2.0.02,7.04,6]heptanyl)ethanone

CAS 38739-89-8C₉H₁₀O

$Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptane-1,5-dicarboxylic acid chemical structure, C9H8O4, CAS 30715-39-0$

Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptane-1,5-dicarboxylic acid

CAS 30715-39-0C₉H₈O₄

Tetracyclo(3.2.0.0^(2,7).0^(4,6))heptane-1-carboxylic acid

CAS 111233-95-5C₈H₈O₂

Tetracyclo[3.2.0.02,7.04,6]heptane-1-carboxylic acid, 5-methyl-(9CI)

CAS 121676-03-7C₉H₁₀O₂

${Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptan-1-yl}methanol chemical structure, C8H10O, CAS 56682-76-9$

{Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptan-1-yl}methanol

CAS 56682-76-9C₈H₁₀O

5-((tert-Butoxycarbonyl)amino)tetracyclo[3.2.0.02,7.04,6]heptane-1-carboxylic acid

CAS 1212140-82-3C₁₃H₁₇NO₄

3-Hydroxytetracyclo[3.2.0.0~2,7~.0~4,6~]heptane-2-carboxylic acid

CAS 72436-79-4C₈H₈O₃

Methyl tetracyclo[3.2.0.0~2,7~.0~4,6~]heptane-3-carboxylate

CAS 94936-64-8C₉H₁₀O₂

3,3-Dimethoxytetracyclo[3.2.0.02,7.04,6]heptane

CAS 21898-75-9C₉H₁₂O₂

$Chloromethyl 5-{[(tert-butoxy)carbonyl]amino}tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptane-1-carboxylate chemical structure, C14H18ClNO4, CAS 2137732-41-1$

Chloromethyl 5-{[(tert-butoxy)carbonyl]amino}tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptane-1-carboxylate

CAS 2137732-41-1C₁₄H₁₈ClNO₄

$Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptane-1-carbaldehyde chemical structure, C8H8O, CAS 1330127-50-8$

Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptane-1-carbaldehyde

CAS 1330127-50-8C₈H₈O

$Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptan-1-amine chemical structure, C7H9N, CAS 916735-18-7$

Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptan-1-amine

CAS 916735-18-7C₇H₉N

$1-{Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptan-1-yl}methanamine chemical structure, C8H11N, CAS 2920138-98-1$

1-{Tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptan-1-yl}methanamine

CAS 2920138-98-1C₈H₁₁N

$1-(Bromomethyl)tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptane chemical structure, C8H9Br, CAS 2920156-87-0$

1-(Bromomethyl)tetracyclo[3.2.0.0^{2,7}.0^{4,6}]heptane

CAS 2920156-87-0C₈H₉Br