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Murcko scaffold

Ring system with 4 rings and 29 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
8
With full pages
3
Scaffold SMILES

O=C(Cc1coc2ccccc12)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1coc2ccccc12)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-(6-Methyl-1-benzofuran-3-yl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C21H18N4O4S, CAS 757221-97-9
2-(6-Methyl-1-benzofuran-3-yl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
CAS 757221-97-9C21H18N4O4S
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C22H20N4O4S, CAS 880785-05-7
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
CAS 880785-05-7C22H20N4O4S
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide chemical structure, C24H24N4O4S, CAS 880787-36-0
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide
CAS 880787-36-0C24H24N4O4S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-(5-methoxy-1-benzofuran-3-yl)acetamide chemical structure, C23H22N4O5S, CAS 873082-57-6
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2-(5-methoxy-1-benzofuran-3-yl)acetamide
CAS 873082-57-6C23H22N4O5S
2-(5-Methoxy-1-benzofuran-3-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide chemical structure, C22H20N4O5S, CAS 873082-55-4
2-(5-Methoxy-1-benzofuran-3-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide
CAS 873082-55-4C22H20N4O5S
2-(6-Methyl-1-benzofuran-3-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide chemical structure, C22H20N4O4S, CAS 880396-28-1
2-(6-Methyl-1-benzofuran-3-yl)-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}acetamide
CAS 880396-28-1C22H20N4O4S
N-{4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl}-2-[5-(propan-2-yl)-1-benzofuran-3-yl]acetamide chemical structure, C24H24N4O4S, CAS 883289-67-6
N-{4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl}-2-[5-(propan-2-yl)-1-benzofuran-3-yl]acetamide
CAS 883289-67-6C24H24N4O4S
2-[5-(Propan-2-yl)-1-benzofuran-3-yl]-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide chemical structure, C23H22N4O4S, CAS 883261-24-3
2-[5-(Propan-2-yl)-1-benzofuran-3-yl]-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]acetamide
CAS 883261-24-3C23H22N4O4S