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Murcko scaffold

Ring system with 4 rings and 23 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
8
With full pages
8
Scaffold SMILES

O=C(c1ccccc1)c1ccc2cccc(-c3ccccn3)n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1ccc2cccc(-c3ccccn3)n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Ethyl 3-(4-chlorobenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate chemical structure, C23H17ClN2O3, CAS 252986-68-8
Ethyl 3-(4-chlorobenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate
CAS 252986-68-8C23H17ClN2O3
Diisopropyl 3-(4-bromobenzoyl)-5-(2-pyridinyl)-1,2-indolizinedicarboxylate chemical structure, C28H25BrN2O5, CAS 618444-11-4
Diisopropyl 3-(4-bromobenzoyl)-5-(2-pyridinyl)-1,2-indolizinedicarboxylate
CAS 618444-11-4C28H25BrN2O5
Ethyl 3-(4-nitrobenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate chemical structure, C23H17N3O5, CAS 252201-19-7
Ethyl 3-(4-nitrobenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate
CAS 252201-19-7C23H17N3O5
Ethyl 3-(4-bromobenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate chemical structure, C23H17BrN2O3, CAS 252201-20-0
Ethyl 3-(4-bromobenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate
CAS 252201-20-0C23H17BrN2O3
Dimethyl 3-(4-bromobenzoyl)-5-(2-pyridinyl)-1,2-indolizinedicarboxylate chemical structure, C24H17BrN2O5, CAS 203588-22-1
Dimethyl 3-(4-bromobenzoyl)-5-(2-pyridinyl)-1,2-indolizinedicarboxylate
CAS 203588-22-1C24H17BrN2O5
Ethyl 3-(4-methylbenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate chemical structure, C24H20N2O3, CAS 853318-53-3
Ethyl 3-(4-methylbenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate
CAS 853318-53-3C24H20N2O3
Ethyl 3-(3-nitrobenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate chemical structure, C23H17N3O5, CAS 853317-40-5
Ethyl 3-(3-nitrobenzoyl)-5-(2-pyridinyl)-1-indolizinecarboxylate
CAS 853317-40-5C23H17N3O5
Diethyl 3-(4-bromobenzoyl)-5-(2-pyridinyl)-1,2-indolizinedicarboxylate chemical structure, C26H21BrN2O5, CAS 853319-40-1
Diethyl 3-(4-bromobenzoyl)-5-(2-pyridinyl)-1,2-indolizinedicarboxylate
CAS 853319-40-1C26H21BrN2O5