Murcko scaffold
Ring system with 4 rings and 25 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 7
- With full pages
- 3
Scaffold SMILES
O=C(Nc1sc2c(c1C(=O)Nc1ccccc1)CCC2)c1ccco1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
![N-[3-[(2-Methoxyphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide chemical structure, C20H18N2O4S, CAS 329935-27-5](/s/HUQSCHCMTTYOIN-UHFFFAOYSA-N.svg)
N-[3-[(2-Methoxyphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide
CAS 329935-27-5C20H18N2O4S
![N-[3-[(2,5-Dimethoxyphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide chemical structure, C21H20N2O5S, CAS 717870-44-5](/s/FAPRTNJKDVMRLQ-UHFFFAOYSA-N.svg)
N-[3-[(2,5-Dimethoxyphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide
CAS 717870-44-5C21H20N2O5S
![N-{3-[(2-Methylphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl}furan-2-carboxamide chemical structure, C20H18N2O3S, CAS 5581-56-6](/s/NHFDXVVSUBBWCA-UHFFFAOYSA-N.svg)
N-{3-[(2-Methylphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl}furan-2-carboxamide
CAS 5581-56-6C20H18N2O3S
![N-[3-[(4-Methylphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide chemical structure, C20H18N2O3S, CAS 403995-51-7](/s/DSJFBHVIBOZJCT-UHFFFAOYSA-N.svg)
N-[3-[(4-Methylphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide
CAS 403995-51-7C20H18N2O3S
![N-[3-[(4-Ethoxyphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide chemical structure, C21H20N2O4S, CAS 309951-91-5](/s/KZRHIIXLKDBPSH-UHFFFAOYSA-N.svg)
N-[3-[(4-Ethoxyphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide
CAS 309951-91-5C21H20N2O4S
![N-[3-[(2-Ethylphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide chemical structure, C21H20N2O3S, CAS 389073-36-3](/s/HMHRHJAJQARIQZ-UHFFFAOYSA-N.svg)
N-[3-[(2-Ethylphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide
CAS 389073-36-3C21H20N2O3S
![N-[3-[(3-Chloro-4-methoxyphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide chemical structure, C20H17ClN2O4S, CAS 491869-85-3](/s/VWOHLOKNXGIQOJ-UHFFFAOYSA-N.svg)
N-[3-[(3-Chloro-4-methoxyphenyl)carbamoyl]-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]furan-2-carboxamide
CAS 491869-85-3C20H17ClN2O4S