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Murcko scaffold

Ring system with 3 rings and 26 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
27
With full pages
5
Scaffold SMILES

O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)NCC1CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)NCC1CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

2-{[(3,4-Dimethoxyphenyl)sulfonyl]anilino}-N-(tetrahydro-2-furanylmethyl)acetamide chemical structure, C21H26N2O6S, CAS 578748-49-9
2-{[(3,4-Dimethoxyphenyl)sulfonyl]anilino}-N-(tetrahydro-2-furanylmethyl)acetamide
CAS 578748-49-9C21H26N2O6S
2-[N-(Benzenesulfonyl)-4-methoxyanilino]-N-(oxolan-2-ylmethyl)acetamide chemical structure, C20H24N2O5S, CAS 6078-34-8
2-[N-(Benzenesulfonyl)-4-methoxyanilino]-N-(oxolan-2-ylmethyl)acetamide
CAS 6078-34-8C20H24N2O5S
2-[N-(Benzenesulfonyl)-2-ethoxyanilino]-N-(oxolan-2-ylmethyl)acetamide chemical structure, C21H26N2O5S, CAS 362000-00-8
2-[N-(Benzenesulfonyl)-2-ethoxyanilino]-N-(oxolan-2-ylmethyl)acetamide
CAS 362000-00-8C21H26N2O5S
2-[N-(Benzenesulfonyl)-3,5-dichloroanilino]-N-(oxolan-2-ylmethyl)acetamide chemical structure, C19H20Cl2N2O4S, CAS 335392-89-7
2-[N-(Benzenesulfonyl)-3,5-dichloroanilino]-N-(oxolan-2-ylmethyl)acetamide
CAS 335392-89-7C19H20Cl2N2O4S
2-(3-Chloro-N-(4-methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C20H23ClN2O4S, CAS 345330-39-4
2-(3-Chloro-N-(4-methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 345330-39-4C20H23ClN2O4S
2-(3-Methyl-N-(4-methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C21H26N2O4S, CAS 425680-07-5
2-(3-Methyl-N-(4-methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 425680-07-5C21H26N2O4S
2-(4-Methoxy-N-(4-methyl-3-nitrophenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C21H25N3O7S, CAS 426223-63-4
2-(4-Methoxy-N-(4-methyl-3-nitrophenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 426223-63-4C21H25N3O7S
2-(N-(4-Methylphenyl)sulfonyl-4-propan-2-ylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C23H30N2O4S, CAS 6445-01-8
2-(N-(4-Methylphenyl)sulfonyl-4-propan-2-ylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 6445-01-8C23H30N2O4S
2-{[(4-Methoxyphenyl)sulfonyl]anilino}-N-(tetrahydro-2-furanylmethyl)acetamide chemical structure, C20H24N2O5S, CAS 428483-51-6
2-{[(4-Methoxyphenyl)sulfonyl]anilino}-N-(tetrahydro-2-furanylmethyl)acetamide
CAS 428483-51-6C20H24N2O5S
2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(oxolan-2-ylmethyl)acetamide chemical structure, C20H23ClN2O5S, CAS 333747-98-1
2-[N-(Benzenesulfonyl)-5-chloro-2-methoxyanilino]-N-(oxolan-2-ylmethyl)acetamide
CAS 333747-98-1C20H23ClN2O5S
2-(N-(4-Methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C20H24N2O4S, CAS 428492-45-9
2-(N-(4-Methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 428492-45-9C20H24N2O4S
2-(2-Methoxy-N-(4-methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C21H26N2O5S, CAS 432006-87-6
2-(2-Methoxy-N-(4-methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 432006-87-6C21H26N2O5S
2-(N-(4-Ethoxyphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C21H26N2O5S, CAS 431910-46-2
2-(N-(4-Ethoxyphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 431910-46-2C21H26N2O5S
2-[N-(Benzenesulfonyl)-3-chloroanilino]-N-(oxolan-2-ylmethyl)acetamide chemical structure, C19H21ClN2O4S, CAS 345327-47-1
2-[N-(Benzenesulfonyl)-3-chloroanilino]-N-(oxolan-2-ylmethyl)acetamide
CAS 345327-47-1C19H21ClN2O4S
2-(4-Chloro-N-(4-methoxyphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C20H23ClN2O5S, CAS 432537-40-1
2-(4-Chloro-N-(4-methoxyphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 432537-40-1C20H23ClN2O5S
2-(N-(3,4-Dimethoxyphenyl)sulfonyl-4-ethoxyanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C23H30N2O7S, CAS 535942-80-4
2-(N-(3,4-Dimethoxyphenyl)sulfonyl-4-ethoxyanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 535942-80-4C23H30N2O7S
2-(3-Chloro-N-(4-chlorophenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C19H20Cl2N2O4S, CAS 446871-56-3
2-(3-Chloro-N-(4-chlorophenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 446871-56-3C19H20Cl2N2O4S
2-[N-(Benzenesulfonyl)-4-iodoanilino]-N-(oxolan-2-ylmethyl)acetamide chemical structure, C19H21IN2O4S, CAS 677014-38-9
2-[N-(Benzenesulfonyl)-4-iodoanilino]-N-(oxolan-2-ylmethyl)acetamide
CAS 677014-38-9C19H21IN2O4S
2-(N-(4-Chlorophenyl)sulfonyl-2-ethoxyanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C21H25ClN2O5S, CAS 694487-74-6
2-(N-(4-Chlorophenyl)sulfonyl-2-ethoxyanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 694487-74-6C21H25ClN2O5S
2-(N-(3,4-Dimethoxyphenyl)sulfonyl-4-fluoroanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C21H25FN2O6S, CAS 640718-12-3
2-(N-(3,4-Dimethoxyphenyl)sulfonyl-4-fluoroanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 640718-12-3C21H25FN2O6S
2-(N-(4-Fluorophenyl)sulfonyl-4-methoxyanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C20H23FN2O5S, CAS 708221-05-0
2-(N-(4-Fluorophenyl)sulfonyl-4-methoxyanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 708221-05-0C20H23FN2O5S
2-[N-(Benzenesulfonyl)-2,5-dichloroanilino]-N-(oxolan-2-ylmethyl)acetamide chemical structure, C19H20Cl2N2O4S, CAS 832680-24-7
2-[N-(Benzenesulfonyl)-2,5-dichloroanilino]-N-(oxolan-2-ylmethyl)acetamide
CAS 832680-24-7C19H20Cl2N2O4S
2-[N-(Benzenesulfonyl)-4-chloro-3-(trifluoromethyl)anilino]-N-(oxolan-2-ylmethyl)acetamide chemical structure, C20H20ClF3N2O4S, CAS 354128-97-5
2-[N-(Benzenesulfonyl)-4-chloro-3-(trifluoromethyl)anilino]-N-(oxolan-2-ylmethyl)acetamide
CAS 354128-97-5C20H20ClF3N2O4S
2-(4-Methoxy-N-(4-methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide chemical structure, C21H26N2O5S, CAS 5669-53-4
2-(4-Methoxy-N-(4-methylphenyl)sulfonylanilino)-N-(oxolan-2-ylmethyl)acetamide
CAS 5669-53-4C21H26N2O5S