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Murcko scaffold

Ring system with 4 rings and 26 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
10
With full pages
1
Scaffold SMILES

O=C(COc1ccc2c(c1)oc(=O)c1ccccc12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccc2c(c1)oc(=O)c1ccccc12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-(4-Bromophenyl)-2-(6-oxobenzo[c]chromen-3-yl)oxyacetamide chemical structure, C21H14BrNO4, CAS 307524-24-9
N-(4-Bromophenyl)-2-(6-oxobenzo[c]chromen-3-yl)oxyacetamide
CAS 307524-24-9C21H14BrNO4
N-(4-Ethoxyphenyl)-2-(6-oxobenzo[c]chromen-3-yloxy)acetamide chemical structure, C23H19NO5, CAS 304870-03-9
N-(4-Ethoxyphenyl)-2-(6-oxobenzo[c]chromen-3-yloxy)acetamide
CAS 304870-03-9C23H19NO5
2-((8-Methoxy-6-oxo-6H-benzo[c]chromen-3-yl)oxy)-N-methyl-N-phenylacetamide chemical structure, C23H19NO5, CAS 670246-20-5
2-((8-Methoxy-6-oxo-6H-benzo[c]chromen-3-yl)oxy)-N-methyl-N-phenylacetamide
CAS 670246-20-5C23H19NO5
N-(4-Fluorophenyl)-2-({6-oxo-6H-benzo[c]chromen-3-yl}oxy)acetamide chemical structure, C21H14FNO4, CAS 670242-33-8
N-(4-Fluorophenyl)-2-({6-oxo-6H-benzo[c]chromen-3-yl}oxy)acetamide
CAS 670242-33-8C21H14FNO4
Butyl 4-[[2-(6-oxobenzo[c]chromen-3-yl)oxyacetyl]amino]benzoate chemical structure, C26H23NO6, CAS 5358-93-0
Butyl 4-[[2-(6-oxobenzo[c]chromen-3-yl)oxyacetyl]amino]benzoate
CAS 5358-93-0C26H23NO6
N-(4-Chloro-2-methoxy-5-methylphenyl)-2-({4-methyl-6-oxo-6H-benzo[c]chromen-3-yl}oxy)acetamide chemical structure, C24H20ClNO5, CAS 500204-00-2
N-(4-Chloro-2-methoxy-5-methylphenyl)-2-({4-methyl-6-oxo-6H-benzo[c]chromen-3-yl}oxy)acetamide
CAS 500204-00-2C24H20ClNO5
N~1~-(3-chlorophenyl)-2-[(6-oxo-6H-benzo[c]chromen-3-yl)oxy]acetamide chemical structure, C21H14ClNO4, CAS 522605-94-3
N~1~-(3-chlorophenyl)-2-[(6-oxo-6H-benzo[c]chromen-3-yl)oxy]acetamide
CAS 522605-94-3C21H14ClNO4
N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[(4-methyl-6-oxo-6H-benzo[c]chromen-3-yl)oxy]acetamide chemical structure, C23H15ClF3NO4, CAS 670242-31-6
N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-[(4-methyl-6-oxo-6H-benzo[c]chromen-3-yl)oxy]acetamide
CAS 670242-31-6C23H15ClF3NO4
Methyl 4-[[2-(6-oxobenzo[c]chromen-3-yl)oxyacetyl]amino]benzoate chemical structure, C23H17NO6, CAS 902020-44-4
Methyl 4-[[2-(6-oxobenzo[c]chromen-3-yl)oxyacetyl]amino]benzoate
CAS 902020-44-4C23H17NO6
2-((6-Oxo-6H-benzo[c]chromen-3-yl)oxy)-N-(3,4,5-trimethoxyphenyl)acetamide chemical structure, C24H21NO7, CAS 903865-44-1
2-((6-Oxo-6H-benzo[c]chromen-3-yl)oxy)-N-(3,4,5-trimethoxyphenyl)acetamide
CAS 903865-44-1C24H21NO7