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Murcko scaffold

Ring system with 5 rings and 30 atoms

24 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
30
Chemicals
24
With full pages
3
Scaffold SMILES

O=C(NCCc1cccc2ccccc12)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1cccc2ccccc12)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

Fmoc-L-1-Naphthylalanine chemical structure, C28H23NO4, CAS 96402-49-2
Fmoc-L-1-Naphthylalanine
CAS 96402-49-2C28H23NO4
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(naphthalen-1-yl)butanoic acid chemical structure, C29H25NO4, CAS 270063-38-2
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(naphthalen-1-yl)butanoic acid
CAS 270063-38-2C29H25NO4
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-naphthalen-1-ylpropanoic acid chemical structure, C28H23NO4, CAS 176036-48-9
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-naphthalen-1-ylpropanoic acid
CAS 176036-48-9C28H23NO4
Fmoc-3-(1-naphthyl)-D-alanine chemical structure, C28H23NO4, CAS 138774-93-3
Fmoc-3-(1-naphthyl)-D-alanine
CAS 138774-93-3C28H23NO4
N-Fmoc-N-methyl-3-(1-naphthyl)-D-alanine chemical structure, C29H25NO4, CAS 193086-27-0
N-Fmoc-N-methyl-3-(1-naphthyl)-D-alanine
CAS 193086-27-0C29H25NO4
Fmoc-(R)-3-Amino-4-(1-naphthyl)-butyric acid chemical structure, C29H25NO4, CAS 269398-89-2
Fmoc-(R)-3-Amino-4-(1-naphthyl)-butyric acid
CAS 269398-89-2C29H25NO4
N-Fmoc-N-methyl-3-(1-naphthyl)-L-alanine chemical structure, C29H25NO4, CAS 1380327-68-3
N-Fmoc-N-methyl-3-(1-naphthyl)-L-alanine
CAS 1380327-68-3C29H25NO4
Methyl (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(naphthalen-1-yl)propanoate chemical structure, C29H25NO4, CAS 1820579-54-1
Methyl (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(naphthalen-1-yl)propanoate
CAS 1820579-54-1C29H25NO4
(R,S)-Fmoc-3-amino-2-(naphthalen-1-yl)-propionic acid chemical structure, C28H23NO4, CAS 1310680-37-5
(R,S)-Fmoc-3-amino-2-(naphthalen-1-yl)-propionic acid
CAS 1310680-37-5C28H23NO4
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methoxynaphthalen-1-yl)propanoic acid chemical structure, C29H25NO5, CAS 1379859-18-3
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methoxynaphthalen-1-yl)propanoic acid
CAS 1379859-18-3C29H25NO5
(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-fluoronaphthalen-1-yl)propanoic acid chemical structure, C28H22FNO4, CAS 2350147-82-7
(2S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-fluoronaphthalen-1-yl)propanoic acid
CAS 2350147-82-7C28H22FNO4
(2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-fluoronaphthalen-1-yl)propanoic acid chemical structure, C28H22FNO4, CAS 2349678-27-7
(2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-fluoronaphthalen-1-yl)propanoic acid
CAS 2349678-27-7C28H22FNO4
(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-methylnaphthalen-1-yl)propanoic acid chemical structure, C29H25NO4, CAS 2350025-85-1
(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-methylnaphthalen-1-yl)propanoic acid
CAS 2350025-85-1C29H25NO4
(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(7-methoxynaphthalen-1-yl)propanoic acid chemical structure, C29H25NO5, CAS 1380445-18-0
(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(7-methoxynaphthalen-1-yl)propanoic acid
CAS 1380445-18-0C29H25NO5
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-methoxynaphthalen-1-yl)propanoic acid chemical structure, C29H25NO5, CAS 1379879-55-6
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-methoxynaphthalen-1-yl)propanoic acid
CAS 1379879-55-6C29H25NO5
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methoxynaphthalen-1-yl)propanoic acid chemical structure, C29H25NO5, CAS 2349832-96-6
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methoxynaphthalen-1-yl)propanoic acid
CAS 2349832-96-6C29H25NO5
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-methoxynaphthalen-1-yl)propanoic acid chemical structure, C29H25NO5, CAS 2350005-41-1
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-methoxynaphthalen-1-yl)propanoic acid
CAS 2350005-41-1C29H25NO5
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-methoxynaphthalen-1-yl)propanoic acid chemical structure, C29H25NO5, CAS 2349445-22-1
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-methoxynaphthalen-1-yl)propanoic acid
CAS 2349445-22-1C29H25NO5
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methoxynaphthalen-1-yl)propanoic acid chemical structure, C29H25NO5, CAS 2349308-67-2
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methoxynaphthalen-1-yl)propanoic acid
CAS 2349308-67-2C29H25NO5
(9H-Fluoren-9-yl)methyl N-[2-hydroxy-2-(naphthalen-1-yl)ethyl]carbamate chemical structure, C27H23NO3, CAS 2763939-81-5
(9H-Fluoren-9-yl)methyl N-[2-hydroxy-2-(naphthalen-1-yl)ethyl]carbamate
CAS 2763939-81-5C27H23NO3
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methylnaphthalen-1-yl)propanoic acid chemical structure, C29H25NO4, CAS 1379837-78-1
2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-methylnaphthalen-1-yl)propanoic acid
CAS 1379837-78-1C29H25NO4
N-alpha-(9-Fluorenylmethyloxycarbonyl)-5-bromo-4-hydroxynaphth-1-ylalanine (Fmoc-L-1Nal(5-Br,4-OH)-OH) chemical structure, C28H22BrNO5, CAS 3012560-52-7
N-alpha-(9-Fluorenylmethyloxycarbonyl)-5-bromo-4-hydroxynaphth-1-ylalanine (Fmoc-L-1Nal(5-Br,4-OH)-OH)
CAS 3012560-52-7C28H22BrNO5
N-alpha-(9-Fluorenylmethyloxycarbonyl)-7-bromo-4-hydroxynaphth-1-ylalanine (Fmoc-L-1Nal(7-Br,4-OH)-OH) chemical structure, C28H22BrNO5, CAS 3012560-53-8
N-alpha-(9-Fluorenylmethyloxycarbonyl)-7-bromo-4-hydroxynaphth-1-ylalanine (Fmoc-L-1Nal(7-Br,4-OH)-OH)
CAS 3012560-53-8C28H22BrNO5
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-hydroxynaphthalen-1-yl)propanoic acid chemical structure, C28H23NO5, CAS 1380508-18-8
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-hydroxynaphthalen-1-yl)propanoic acid
CAS 1380508-18-8C28H23NO5