Murcko scaffold
Ring system with 4 rings and 18 atoms
31 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 18
- Chemicals
- 31
- With full pages
- 2
Scaffold SMILES
c1ccc(C2SCc3nc4ccccc4n32)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 31 of 31 chemicals
1-(2',6'-Difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole
CAS 138226-12-7C15H10F2N2S
![1-(4-Chlorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C15H11ClN2S, CAS 136994-87-1](/s/IKOAISDPONXJQG-UHFFFAOYSA-N.svg)
1-(4-Chlorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-87-1C15H11ClN2S
![1-(2-Bromophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C15H11BrN2S, CAS 136994-82-6](/s/CTFKPXQJNIZGEL-UHFFFAOYSA-N.svg)
1-(2-Bromophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-82-6C15H11BrN2S
![1-(4-Fluorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C15H11FN2S, CAS 136994-91-7](/s/TUEVGHMVASKCCE-UHFFFAOYSA-N.svg)
1-(4-Fluorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-91-7C15H11FN2S
![1-(3-Bromophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C15H11BrN2S, CAS 136994-83-7](/s/WMEXLDJBKXUZPX-UHFFFAOYSA-N.svg)
1-(3-Bromophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-83-7C15H11BrN2S
![1-(4-Bromophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C15H11BrN2S, CAS 136994-84-8](/s/VAZZLVFERHJLEV-UHFFFAOYSA-N.svg)
1-(4-Bromophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-84-8C15H11BrN2S
![1-(3-Methylphenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C16H14N2S, CAS 136994-96-2](/s/DXMCBXOONDVGLN-UHFFFAOYSA-N.svg)
1-(3-Methylphenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-96-2C16H14N2S
![1-(2-Chlorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C15H11ClN2S, CAS 136994-85-9](/s/NMTHEQHYUCNJIO-UHFFFAOYSA-N.svg)
1-(2-Chlorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-85-9C15H11ClN2S
![1-(3-Chlorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C15H11ClN2S, CAS 136994-86-0](/s/FBYKUBSWTGLUOJ-UHFFFAOYSA-N.svg)
1-(3-Chlorophenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-86-0C15H11ClN2S
1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(3-methoxyphenyl)-
CAS 136994-93-9C16H14N2OS
1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(2-chloro-6-fluorophenyl)-
CAS 138226-14-9C15H10ClFN2S
![1-(2-Methylphenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C16H14N2S, CAS 136994-95-1](/s/ZTMUGRMOFPWTFX-UHFFFAOYSA-N.svg)
1-(2-Methylphenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136994-95-1C16H14N2S
![1-(2-(Trifluoromethyl)phenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C16H11F3N2S, CAS 136995-00-1](/s/XRQBDCFVJBPNHH-UHFFFAOYSA-N.svg)
1-(2-(Trifluoromethyl)phenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136995-00-1C16H11F3N2S
![1-(3-(Trifluoromethyl)phenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C16H11F3N2S, CAS 136995-01-2](/s/XTLVALLIRNCOGM-UHFFFAOYSA-N.svg)
1-(3-(Trifluoromethyl)phenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 136995-01-2C16H11F3N2S
![1H,3H-Thiazolo[3,4-a]benzimidazole, 1-[4-(trifluoromethyl)phenyl]- chemical structure, C16H11F3N2S, CAS 136995-02-3](/s/MYYGTKQABBLHEM-UHFFFAOYSA-N.svg)
1H,3H-Thiazolo[3,4-a]benzimidazole, 1-[4-(trifluoromethyl)phenyl]-
CAS 136995-02-3C16H11F3N2S
1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(3-fluorophenyl)-
CAS 136994-90-6C15H11FN2S
1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(2-fluorophenyl)-
CAS 136994-89-3C15H11FN2S
![1-(3-Hydroxyphenyl)-1H,3H-thiazolo[3,4-a]benzimidazole chemical structure, C15H12N2OS, CAS 136994-92-8](/s/YVSMVNPXTNBYHV-UHFFFAOYSA-N.svg)
1-(3-Hydroxyphenyl)-1H,3H-thiazolo[3,4-a]benzimidazole
CAS 136994-92-8C15H12N2OS
![1-(2-Chloro-5-(hydroxy(oxido)amino)phenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole chemical structure, C15H10ClN3O2S, CAS 138226-16-1](/s/MYXKHRSTGNIYQC-UHFFFAOYSA-N.svg)
1-(2-Chloro-5-(hydroxy(oxido)amino)phenyl)-3H-[1,3]thiazolo[3,4-a]benzimidazole
CAS 138226-16-1C15H10ClN3O2S
![1-(4-Cyanophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole chemical structure, C16H11N3S, CAS 136994-88-2](/s/QTXIUOCGAKXPES-UHFFFAOYSA-N.svg)
1-(4-Cyanophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole
CAS 136994-88-2C16H11N3S
1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(2-nitrophenyl)-
CAS 136994-97-3C15H11N3O2S
1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(3-nitrophenyl)-
CAS 136994-98-4C15H11N3O2S
1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(4-nitrophenyl)-
CAS 136994-99-5C15H11N3O2S
![1-(3-Cyanophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole chemical structure, C16H11N3S, CAS 137015-79-3](/s/IUXOVSWNHQLVOW-UHFFFAOYSA-N.svg)
1-(3-Cyanophenyl)-1H,3H-thiazolo[3,4-a]benzimidazole
CAS 137015-79-3C16H11N3S
- (R)-1-(2,6-Difluorophenyl)-1H,3H-thiazolo(3,4-a)benzimidazole194161-13-2C15H10F2N2S
- 1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(2,6-difluorophenyl)-, (S)-194161-14-3C15H10F2N2S
- 1H,3H-Thiazolo(3,4-a)benzimidazole, 3-methyl-1-phenyl-, (1R,3R)-rel-217321-87-4C16H14N2S
- 1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(2,6-dichlorophenyl)-3-methyl-, (1R,3R)-rel-217321-95-4C16H12Cl2N2S
- 1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(2-chloro-6-fluorophenyl)-3-methyl-, (1R,3R)-rel-217322-00-4C16H12ClFN2S
- 1H,3H-Thiazolo(3,4-a)benzimidazole, 1-(2,6-difluorophenyl)-3-methyl-, (1R,3R)-rel-217322-04-8C16H12F2N2S
- 1-(2,6-Difluorophenyl)-6-(trifluoromethyl)-3H-thiazolo[3,4-a]benzimidazole246148-68-5C16H9F5N2S
Related scaffolds
Same ring framework with different atoms or bond orders
