Murcko scaffold
Thermopsine scaffold
10 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 18
- Chemicals
- 10
- With full pages
- 4
Scaffold SMILES
O=c1cccc2n1CC1CC2CN2CCCCC12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
Thermopsine
CAS 855841-99-5C15H20N2O
13-Acetoxyanagyrine
CAS 77077-09-9C17H22N2O3
Baptifoline
CAS 732-50-3C15H20N2O2
7,14-Methano-2H,11H-dipyrido(1,2-a:1',2'-e)(1,5)diazocin-11-one, 1,3,4,6,7,13,14,14a-octahydro-2-hydroxy-
CAS 27773-56-4C15H20N2O2
(-)-Thermopsine
CAS 486-90-8C15H20N2O
(+)-Thermopsine
CAS 53584-33-1C15H20N2O
Anagyrine
CAS 486-89-5C15H20N2O
Anagyrine, monohydrobromide
CAS 33478-03-4C15H21BrN2O
Anagyrine hydrochloride
CAS 74195-83-8C15H21ClN2O
Anagyrine perchlorate-55%
CAS 3000-67-7C15H21ClN2O5
Related scaffolds
Same ring framework with different atoms or bond orders
O=C1CCCC2C3CC(CN12)C1CCCCN1C36 chemicals
C1CCN2CC3CC(CN4CCCCC34)C2C16 chemicals
c1ccc2c(c1)OC1CC2Oc2ccccc212 chemicals
C1=C2CCCNC2C2CC1C1CCCCN1C22 chemicals
C1=CN2CC3CC(CN4CCCCC34)C2CC11 chemical
O=C1c2ccccc2C2Oc3ccccc3C1O21 chemical
O=C1C=CN2CC3CC(CN4CCCCC34)C2C11 chemical
c1ccc2c(c1)OC1OC2Oc2ccccc211 chemical
c1ccc2c(c1)CN1CN2Cc2ccccc211 chemical
c1ccc2c(c1)CC1NC2Cc2ccccc211 chemical
C1=C2C3CC(CN2CCC1)C1CCCCN1C31 chemical
O=C1C2CC(CN3CCCCC23)C2CCCCN121 chemical