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Murcko scaffold

Ring system with 4 rings and 29 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
9
With full pages
1
Scaffold SMILES

O=C(CC1C(=O)Nc2ccccc2N1C(=O)c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CC1C(=O)Nc2ccccc2N1C(=O)c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-(1-Benzoyl-3-oxo-1,2,3,4-tetrahydro-2-quinoxalinyl)-N-(2-methoxyphenyl)acetamide chemical structure, C24H21N3O4, CAS 1008462-73-4
2-(1-Benzoyl-3-oxo-1,2,3,4-tetrahydro-2-quinoxalinyl)-N-(2-methoxyphenyl)acetamide
CAS 1008462-73-4C24H21N3O4
2-{1-[(4-Bromophenyl)carbonyl]-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl}-N-(3,4-dimethylphenyl)acetamide chemical structure, C25H22BrN3O3, CAS 1030610-73-1
2-{1-[(4-Bromophenyl)carbonyl]-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl}-N-(3,4-dimethylphenyl)acetamide
CAS 1030610-73-1C25H22BrN3O3
2-(1-Benzoyl-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-(4-bromophenyl)acetamide chemical structure, C23H18BrN3O3, CAS 1039729-49-1
2-(1-Benzoyl-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-(4-bromophenyl)acetamide
CAS 1039729-49-1C23H18BrN3O3
2-(1-(4-Ethoxybenzoyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide chemical structure, C26H22F3N3O4, CAS 1007998-55-1
2-(1-(4-Ethoxybenzoyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide
CAS 1007998-55-1C26H22F3N3O4
N-(4-Bromophenyl)-2-{1-[(4-chlorophenyl)carbonyl]-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl}acetamide chemical structure, C23H17BrClN3O3, CAS 1219264-68-2
N-(4-Bromophenyl)-2-{1-[(4-chlorophenyl)carbonyl]-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl}acetamide
CAS 1219264-68-2C23H17BrClN3O3
N-(2-Ethoxyphenyl)-2-[1-(3-nitrobenzoyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]acetamide chemical structure, C25H22N4O6, CAS 1219349-81-1
N-(2-Ethoxyphenyl)-2-[1-(3-nitrobenzoyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]acetamide
CAS 1219349-81-1C25H22N4O6
2-{3-Oxo-1-[(3,4,5-trimethoxyphenyl)carbonyl]-1,2,3,4-tetrahydroquinoxalin-2-yl}-N-phenylacetamide chemical structure, C26H25N3O6, CAS 1219275-98-5
2-{3-Oxo-1-[(3,4,5-trimethoxyphenyl)carbonyl]-1,2,3,4-tetrahydroquinoxalin-2-yl}-N-phenylacetamide
CAS 1219275-98-5C26H25N3O6
N-(4-Bromophenyl)-2-{1-[(2-chlorophenyl)carbonyl]-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl}acetamide chemical structure, C23H17BrClN3O3, CAS 1219333-38-6
N-(4-Bromophenyl)-2-{1-[(2-chlorophenyl)carbonyl]-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl}acetamide
CAS 1219333-38-6C23H17BrClN3O3
2-[1-(4-Bromobenzoyl)-3-oxo-1,2,3,4-tetrahydro-2-quinoxalinyl]-N~1~-(3-chlorophenyl)acetamide chemical structure, C23H17BrClN3O3, CAS 1219143-24-4
2-[1-(4-Bromobenzoyl)-3-oxo-1,2,3,4-tetrahydro-2-quinoxalinyl]-N~1~-(3-chlorophenyl)acetamide
CAS 1219143-24-4C23H17BrClN3O3