CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 22 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
10
With full pages
1
Scaffold SMILES

c1ccc(COc2ncnc3c2ncn3C2CCCO2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(COc2ncnc3c2ncn3C2CCCO2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

O(6)-benzyl-2'-deoxyguanosine chemical structure, C17H19N5O4, CAS 129732-90-7
O(6)-benzyl-2'-deoxyguanosine
CAS 129732-90-7C17H19N5O4
2'-Deoxy-6-O-(2-hydroxy-1-phenylethyl)guanosine chemical structure, C18H21N5O5, CAS 117456-68-5
2'-Deoxy-6-O-(2-hydroxy-1-phenylethyl)guanosine
CAS 117456-68-5C18H21N5O5
Guanosine, N-acetyl-6-O-(phenylmethyl)- chemical structure, C19H21N5O6, CAS 156998-80-0
Guanosine, N-acetyl-6-O-(phenylmethyl)-
CAS 156998-80-0C19H21N5O6
O6-benzyl guanosine chemical structure, C17H19N5O5, CAS 4552-61-8
O6-benzyl guanosine
CAS 4552-61-8C17H19N5O5
Guanosine, 6-O-[(4-chlorophenyl)methyl]- chemical structure, C17H18ClN5O5, CAS 88158-11-6
Guanosine, 6-O-[(4-chlorophenyl)methyl]-
CAS 88158-11-6C17H18ClN5O5
Guanosine, 6-O-[(4-methylphenyl)methyl]- chemical structure, C18H21N5O5, CAS 79384-30-8
Guanosine, 6-O-[(4-methylphenyl)methyl]-
CAS 79384-30-8C18H21N5O5
(2R,3S,5R)-5-(2-Fluoro-6-phenylmethoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol chemical structure, C17H17FN4O4, CAS 144640-76-6
(2R,3S,5R)-5-(2-Fluoro-6-phenylmethoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
CAS 144640-76-6C17H17FN4O4
3',5'-Di-O-acetyl O6-Benzyl-2'-deoxyguanosine chemical structure, C21H23N5O6, CAS 144640-75-5
3',5'-Di-O-acetyl O6-Benzyl-2'-deoxyguanosine
CAS 144640-75-5C21H23N5O6
Inosine, 6-O-(phenylmethyl)-, 5a(2)-[hydrogen P-(phosphonomethyl)phosphonate] chemical structure, C18H22N4O10P2, CAS 1802226-87-4
Inosine, 6-O-(phenylmethyl)-, 5a(2)-[hydrogen P-(phosphonomethyl)phosphonate]
CAS 1802226-87-4C18H22N4O10P2
9-[(2R,4S,5R)-4-[(1,1-Dimethylethyl)dimethylsilyl]-5-[[(1,1-dimethylethyl)dimethylsilyl]methyl]tetrahydro-2-furanyl]-6-(phenylmethoxy)-9H-purin-2-amine chemical structure, C29H47N5O2Si2, CAS 1000788-50-0
9-[(2R,4S,5R)-4-[(1,1-Dimethylethyl)dimethylsilyl]-5-[[(1,1-dimethylethyl)dimethylsilyl]methyl]tetrahydro-2-furanyl]-6-(phenylmethoxy)-9H-purin-2-amine
CAS 1000788-50-0C29H47N5O2Si2