Murcko scaffold
1-(2-Oxo-2-phenylethyl)pyridin-2(1H)-one scaffold
19 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 19
- With full pages
- 5
Scaffold SMILES
O=C(Cn1ccccc1=O)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 19 of 19 chemicals
1-[2-(4-Fluorophenyl)-2-oxoethyl]pyridin-2(1H)-one
CAS 325-95-1C13H10FNO2
1-(2-Oxo-2-phenylethyl)pyridin-2(1H)-one
CAS 952-75-0C13H11NO2
3-Nitro-1-(2-oxo-2-phenyl-ethyl)-1H-pyridin-2-one
CAS 367454-75-9C13H10N2O4
5-Chloro-1-[2-(4-chlorophenyl)-2-oxoethyl]-2(1H)-pyridinone
CAS 108664-64-8C13H9Cl2NO2
Methyl 1-[2-(4-chlorophenyl)-2-oxoethyl]-6-oxo-1,6-dihydro-3-pyridinecarboxylate
CAS 108664-62-6C15H12ClNO4
Methyl 1-[2-(4-chlorophenyl)-2-oxoethyl]-2-oxo-1,2-dihydro-3-pyridinecarboxylate
CAS 339024-57-6C15H12ClNO4
Methyl 1-[2-(2,4-dichlorophenyl)-2-oxoethyl]-2-oxo-1,2-dihydro-3-pyridinecarboxylate
CAS 339024-59-8C15H11Cl2NO4
2(1H)-Pyridinone, 1-(2-(4-chlorophenyl)-1-methyl-2-oxoethyl)-
CAS 108664-56-8C14H12ClNO2
1-[2-(4-Chlorophenyl)-2-oxoethyl]-2(1H)-pyridinone
CAS 108664-55-7C13H10ClNO2
1-[2-(4-Methylphenyl)-2-oxoethyl]pyridin-2-one
CAS 61656-98-2C14H13NO2
1-[2-(4-Chlorophenyl)-2-oxoethyl]-6-oxo-1,6-dihydro-3-pyridinecarboxylic acid
CAS 400088-57-5C14H10ClNO4
2(1H)-Pyridinone, 1-[2-(4-bromophenyl)-2-oxoethyl]-
CAS 955-95-3C13H10BrNO2
2(1H)-Pyridinone, 4-methyl-1-(2-oxo-2-phenylethyl)-
CAS 61656-99-3C14H13NO2
2(1H)-Pyridinone, 1-[2-(4-bromophenyl)-2-oxoethyl]-4-methyl-
CAS 61657-00-9C14H12BrNO2
1-(2-(4-Ethylphenyl)-2-oxoethyl)pyridin-2(1H)-one
CAS 925401-49-6C15H15NO2
N-[[4-[2-[2-Oxo-5-(trifluoromethyl)-1(2H)-pyridinyl]acetyl]phenyl]methyl]acetamide
CAS 923255-85-0C17H15F3N2O3
Ethyl 4-chloro-6-ethyl-2-oxo-1-(2-oxo-2-phenylethyl)-1,2-dihydropyridine-3-carboxylate
CAS 1186188-52-2C18H18ClNO4
5-Bromo-1-(2-oxo-2-phenylethyl)-2(1H)-pyridinone
CAS 1461745-50-5C13H10BrNO2
1-(2-(3-Nitrophenyl)-2-oxoethyl)pyridin-2(1H)-one
CAS 213766-47-3C13H10N2O4