CompoundList
Murcko scaffold

1-(2-Oxo-2-phenylethyl)pyridin-2(1H)-one scaffold

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
19
With full pages
5
Scaffold SMILES

O=C(Cn1ccccc1=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Murcko scaffold O=C(Cn1ccccc1=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

1-[2-(4-Fluorophenyl)-2-oxoethyl]pyridin-2(1H)-one chemical structure, C13H10FNO2, CAS 325-95-1
1-[2-(4-Fluorophenyl)-2-oxoethyl]pyridin-2(1H)-one
CAS 325-95-1C13H10FNO2
1-(2-Oxo-2-phenylethyl)pyridin-2(1H)-one chemical structure, C13H11NO2, CAS 952-75-0
1-(2-Oxo-2-phenylethyl)pyridin-2(1H)-one
CAS 952-75-0C13H11NO2
3-Nitro-1-(2-oxo-2-phenyl-ethyl)-1H-pyridin-2-one chemical structure, C13H10N2O4, CAS 367454-75-9
3-Nitro-1-(2-oxo-2-phenyl-ethyl)-1H-pyridin-2-one
CAS 367454-75-9C13H10N2O4
5-Chloro-1-[2-(4-chlorophenyl)-2-oxoethyl]-2(1H)-pyridinone chemical structure, C13H9Cl2NO2, CAS 108664-64-8
5-Chloro-1-[2-(4-chlorophenyl)-2-oxoethyl]-2(1H)-pyridinone
CAS 108664-64-8C13H9Cl2NO2
Methyl 1-[2-(4-chlorophenyl)-2-oxoethyl]-6-oxo-1,6-dihydro-3-pyridinecarboxylate chemical structure, C15H12ClNO4, CAS 108664-62-6
Methyl 1-[2-(4-chlorophenyl)-2-oxoethyl]-6-oxo-1,6-dihydro-3-pyridinecarboxylate
CAS 108664-62-6C15H12ClNO4
Methyl 1-[2-(4-chlorophenyl)-2-oxoethyl]-2-oxo-1,2-dihydro-3-pyridinecarboxylate chemical structure, C15H12ClNO4, CAS 339024-57-6
Methyl 1-[2-(4-chlorophenyl)-2-oxoethyl]-2-oxo-1,2-dihydro-3-pyridinecarboxylate
CAS 339024-57-6C15H12ClNO4
Methyl 1-[2-(2,4-dichlorophenyl)-2-oxoethyl]-2-oxo-1,2-dihydro-3-pyridinecarboxylate chemical structure, C15H11Cl2NO4, CAS 339024-59-8
Methyl 1-[2-(2,4-dichlorophenyl)-2-oxoethyl]-2-oxo-1,2-dihydro-3-pyridinecarboxylate
CAS 339024-59-8C15H11Cl2NO4
2(1H)-Pyridinone, 1-(2-(4-chlorophenyl)-1-methyl-2-oxoethyl)- chemical structure, C14H12ClNO2, CAS 108664-56-8
2(1H)-Pyridinone, 1-(2-(4-chlorophenyl)-1-methyl-2-oxoethyl)-
CAS 108664-56-8C14H12ClNO2
1-[2-(4-Chlorophenyl)-2-oxoethyl]-2(1H)-pyridinone chemical structure, C13H10ClNO2, CAS 108664-55-7
1-[2-(4-Chlorophenyl)-2-oxoethyl]-2(1H)-pyridinone
CAS 108664-55-7C13H10ClNO2
1-[2-(4-Methylphenyl)-2-oxoethyl]pyridin-2-one chemical structure, C14H13NO2, CAS 61656-98-2
1-[2-(4-Methylphenyl)-2-oxoethyl]pyridin-2-one
CAS 61656-98-2C14H13NO2
1-[2-(4-Chlorophenyl)-2-oxoethyl]-6-oxo-1,6-dihydro-3-pyridinecarboxylic acid chemical structure, C14H10ClNO4, CAS 400088-57-5
1-[2-(4-Chlorophenyl)-2-oxoethyl]-6-oxo-1,6-dihydro-3-pyridinecarboxylic acid
CAS 400088-57-5C14H10ClNO4
2(1H)-Pyridinone, 1-[2-(4-bromophenyl)-2-oxoethyl]- chemical structure, C13H10BrNO2, CAS 955-95-3
2(1H)-Pyridinone, 1-[2-(4-bromophenyl)-2-oxoethyl]-
CAS 955-95-3C13H10BrNO2
2(1H)-Pyridinone, 4-methyl-1-(2-oxo-2-phenylethyl)- chemical structure, C14H13NO2, CAS 61656-99-3
2(1H)-Pyridinone, 4-methyl-1-(2-oxo-2-phenylethyl)-
CAS 61656-99-3C14H13NO2
2(1H)-Pyridinone, 1-[2-(4-bromophenyl)-2-oxoethyl]-4-methyl- chemical structure, C14H12BrNO2, CAS 61657-00-9
2(1H)-Pyridinone, 1-[2-(4-bromophenyl)-2-oxoethyl]-4-methyl-
CAS 61657-00-9C14H12BrNO2
1-(2-(4-Ethylphenyl)-2-oxoethyl)pyridin-2(1H)-one chemical structure, C15H15NO2, CAS 925401-49-6
1-(2-(4-Ethylphenyl)-2-oxoethyl)pyridin-2(1H)-one
CAS 925401-49-6C15H15NO2
N-[[4-[2-[2-Oxo-5-(trifluoromethyl)-1(2H)-pyridinyl]acetyl]phenyl]methyl]acetamide chemical structure, C17H15F3N2O3, CAS 923255-85-0
N-[[4-[2-[2-Oxo-5-(trifluoromethyl)-1(2H)-pyridinyl]acetyl]phenyl]methyl]acetamide
CAS 923255-85-0C17H15F3N2O3
Ethyl 4-chloro-6-ethyl-2-oxo-1-(2-oxo-2-phenylethyl)-1,2-dihydropyridine-3-carboxylate chemical structure, C18H18ClNO4, CAS 1186188-52-2
Ethyl 4-chloro-6-ethyl-2-oxo-1-(2-oxo-2-phenylethyl)-1,2-dihydropyridine-3-carboxylate
CAS 1186188-52-2C18H18ClNO4
5-Bromo-1-(2-oxo-2-phenylethyl)-2(1H)-pyridinone chemical structure, C13H10BrNO2, CAS 1461745-50-5
5-Bromo-1-(2-oxo-2-phenylethyl)-2(1H)-pyridinone
CAS 1461745-50-5C13H10BrNO2
1-(2-(3-Nitrophenyl)-2-oxoethyl)pyridin-2(1H)-one chemical structure, C13H10N2O4, CAS 213766-47-3
1-(2-(3-Nitrophenyl)-2-oxoethyl)pyridin-2(1H)-one
CAS 213766-47-3C13H10N2O4