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Murcko scaffold

Ring system with 4 rings and 26 atoms

34 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
34
With full pages
5
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccc(-c2nc3ccccc3o2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1ccc(-c2nc3ccccc3o2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

2-(2,3-Dimethylphenoxy)-N-[4-(5-ethyl-1,3-benzoxazol-2-yl)phenyl]acetamide chemical structure, C25H24N2O3, CAS 442522-59-0
2-(2,3-Dimethylphenoxy)-N-[4-(5-ethyl-1,3-benzoxazol-2-yl)phenyl]acetamide
CAS 442522-59-0C25H24N2O3
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2,6-dimethylphenoxy)acetamide chemical structure, C23H20N2O3, CAS 434293-27-3
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2,6-dimethylphenoxy)acetamide
CAS 434293-27-3C23H20N2O3
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(4-bromophenoxy)acetamide chemical structure, C21H15BrN2O3, CAS 5838-75-5
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(4-bromophenoxy)acetamide
CAS 5838-75-5C21H15BrN2O3
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2,5-dimethylphenoxy)acetamide chemical structure, C23H20N2O3, CAS 518010-16-7
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2,5-dimethylphenoxy)acetamide
CAS 518010-16-7C23H20N2O3
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(3-nitrophenoxy)acetamide chemical structure, C21H15N3O5, CAS 692264-63-4
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(3-nitrophenoxy)acetamide
CAS 692264-63-4C21H15N3O5
N-[4-(5,7-Dichloro-1,3-benzoxazol-2-yl)phenyl]-2-(2-methylphenoxy)acetamide chemical structure, C22H16Cl2N2O3, CAS 431939-29-6
N-[4-(5,7-Dichloro-1,3-benzoxazol-2-yl)phenyl]-2-(2-methylphenoxy)acetamide
CAS 431939-29-6C22H16Cl2N2O3
N-[4-(5-Chloro-1,3-benzoxazol-2-yl)phenyl]-2-(2,4-dimethylphenoxy)acetamide chemical structure, C23H19ClN2O3, CAS 431940-26-0
N-[4-(5-Chloro-1,3-benzoxazol-2-yl)phenyl]-2-(2,4-dimethylphenoxy)acetamide
CAS 431940-26-0C23H19ClN2O3
2-(2,4-Dimethyl-6-nitrophenoxy)-N-[4-(5-propan-2-yl-1,3-benzoxazol-2-yl)phenyl]acetamide chemical structure, C26H25N3O5, CAS 431980-90-4
2-(2,4-Dimethyl-6-nitrophenoxy)-N-[4-(5-propan-2-yl-1,3-benzoxazol-2-yl)phenyl]acetamide
CAS 431980-90-4C26H25N3O5
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2,4-dimethylphenoxy)acetamide chemical structure, C23H20N2O3, CAS 432005-92-0
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2,4-dimethylphenoxy)acetamide
CAS 432005-92-0C23H20N2O3
2-(4-Nitrophenoxy)-N-[4-(5-propan-2-yl-1,3-benzoxazol-2-yl)phenyl]acetamide chemical structure, C24H21N3O5, CAS 432016-85-8
2-(4-Nitrophenoxy)-N-[4-(5-propan-2-yl-1,3-benzoxazol-2-yl)phenyl]acetamide
CAS 432016-85-8C24H21N3O5
2-(2,4-Dimethylphenoxy)-N-[4-(5-ethyl-1,3-benzoxazol-2-yl)phenyl]acetamide chemical structure, C25H24N2O3, CAS 432017-20-4
2-(2,4-Dimethylphenoxy)-N-[4-(5-ethyl-1,3-benzoxazol-2-yl)phenyl]acetamide
CAS 432017-20-4C25H24N2O3
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(3,5-dimethylphenoxy)acetamide chemical structure, C23H20N2O3, CAS 432017-71-5
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(3,5-dimethylphenoxy)acetamide
CAS 432017-71-5C23H20N2O3
N-[4-(5,7-Dimethyl-1,3-benzoxazol-2-yl)phenyl]-2-(4-methylphenoxy)acetamide chemical structure, C24H22N2O3, CAS 431929-42-9
N-[4-(5,7-Dimethyl-1,3-benzoxazol-2-yl)phenyl]-2-(4-methylphenoxy)acetamide
CAS 431929-42-9C24H22N2O3
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2,3-dimethylphenoxy)acetamide chemical structure, C23H20N2O3, CAS 431929-82-7
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2,3-dimethylphenoxy)acetamide
CAS 431929-82-7C23H20N2O3
2-(2,4-Dimethylphenoxy)-N-[4-(5-methyl-1,3-benzoxazol-2-yl)phenyl]acetamide chemical structure, C24H22N2O3, CAS 431996-67-7
2-(2,4-Dimethylphenoxy)-N-[4-(5-methyl-1,3-benzoxazol-2-yl)phenyl]acetamide
CAS 431996-67-7C24H22N2O3
2-(4-Chloro-2-methylphenoxy)-N-[4-(6-methyl-1,3-benzoxazol-2-yl)phenyl]acetamide chemical structure, C23H19ClN2O3, CAS 425685-26-3
2-(4-Chloro-2-methylphenoxy)-N-[4-(6-methyl-1,3-benzoxazol-2-yl)phenyl]acetamide
CAS 425685-26-3C23H19ClN2O3
N-[4-(5-Methyl-1,3-benzoxazol-2-yl)phenyl]-2-(3-methylphenoxy)acetamide chemical structure, C23H20N2O3, CAS 428461-29-4
N-[4-(5-Methyl-1,3-benzoxazol-2-yl)phenyl]-2-(3-methylphenoxy)acetamide
CAS 428461-29-4C23H20N2O3
N-[4-(6-Methyl-1,3-benzoxazol-2-yl)phenyl]-2-(3-methylphenoxy)acetamide chemical structure, C23H20N2O3, CAS 428488-44-2
N-[4-(6-Methyl-1,3-benzoxazol-2-yl)phenyl]-2-(3-methylphenoxy)acetamide
CAS 428488-44-2C23H20N2O3
2-(4-Methoxyphenoxy)-N-[4-(6-methyl-1,3-benzoxazol-2-yl)phenyl]acetamide chemical structure, C23H20N2O4, CAS 364598-25-4
2-(4-Methoxyphenoxy)-N-[4-(6-methyl-1,3-benzoxazol-2-yl)phenyl]acetamide
CAS 364598-25-4C23H20N2O4
N-[4-(5-Ethyl-1,3-benzoxazol-2-yl)phenyl]-2-(2-methylphenoxy)acetamide chemical structure, C24H22N2O3, CAS 420829-87-4
N-[4-(5-Ethyl-1,3-benzoxazol-2-yl)phenyl]-2-(2-methylphenoxy)acetamide
CAS 420829-87-4C24H22N2O3
N-[4-(1,3-Benzoxazol-2-yl)-3-hydroxyphenyl]-2-(4-bromophenoxy)acetamide chemical structure, C21H15BrN2O4, CAS 6002-22-8
N-[4-(1,3-Benzoxazol-2-yl)-3-hydroxyphenyl]-2-(4-bromophenoxy)acetamide
CAS 6002-22-8C21H15BrN2O4
N-[4-(1,3-Benzoxazol-2-yl)-3-hydroxyphenyl]-2-(4-ethylphenoxy)acetamide chemical structure, C23H20N2O4, CAS 423750-84-9
N-[4-(1,3-Benzoxazol-2-yl)-3-hydroxyphenyl]-2-(4-ethylphenoxy)acetamide
CAS 423750-84-9C23H20N2O4
N-[4-(6-Methyl-1,3-benzoxazol-2-yl)phenyl]-2-(2-methylphenoxy)acetamide chemical structure, C23H20N2O3, CAS 423149-16-0
N-[4-(6-Methyl-1,3-benzoxazol-2-yl)phenyl]-2-(2-methylphenoxy)acetamide
CAS 423149-16-0C23H20N2O3
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2-methylphenoxy)acetamide chemical structure, C22H18N2O3, CAS 364737-24-6
N-[4-(1,3-Benzoxazol-2-yl)phenyl]-2-(2-methylphenoxy)acetamide
CAS 364737-24-6C22H18N2O3