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Murcko scaffold

Ring system with 5 rings and 15 atoms

16 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
15
Chemicals
16
With full pages
2
Scaffold SMILES

c1nnc(C23CC4CC(CC(C4)C2)C3)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nnc(C23CC4CC(CC(C4)C2)C3)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

5-(Adamantan-1-yl)-1,3,4-thiadiazol-2-amine chemical structure, C12H17N3S, CAS 26526-57-8
5-(Adamantan-1-yl)-1,3,4-thiadiazol-2-amine
CAS 26526-57-8C12H17N3S
5-(1-Adamantyl)-N-methyl-1,3,4-thiadiazol-2-amine chemical structure, C13H19N3S, CAS 156604-69-2
5-(1-Adamantyl)-N-methyl-1,3,4-thiadiazol-2-amine
CAS 156604-69-2C13H19N3S
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]pentanamide chemical structure, C17H25N3OS, CAS 392240-95-8
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]pentanamide
CAS 392240-95-8C17H25N3OS
N-(5-((3r,5r,7r)-Adamantan-1-yl)-1,3,4-thiadiazol-2-yl)-N-methylacetamide chemical structure, C15H21N3OS, CAS 392320-77-3
N-(5-((3r,5r,7r)-Adamantan-1-yl)-1,3,4-thiadiazol-2-yl)-N-methylacetamide
CAS 392320-77-3C15H21N3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-ethylbutanamide chemical structure, C18H27N3OS, CAS 392244-12-1
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-ethylbutanamide
CAS 392244-12-1C18H27N3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-ethyl-N-methylbutanamide chemical structure, C19H29N3OS, CAS 392320-85-3
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-ethyl-N-methylbutanamide
CAS 392320-85-3C19H29N3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-chloro-N-methylacetamide chemical structure, C15H20ClN3OS, CAS 392320-79-5
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-chloro-N-methylacetamide
CAS 392320-79-5C15H20ClN3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-chloropropanamide chemical structure, C15H20ClN3OS, CAS 391866-03-8
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-chloropropanamide
CAS 391866-03-8C15H20ClN3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-chloroacetamide chemical structure, C14H18ClN3OS, CAS 392240-94-7
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-2-chloroacetamide
CAS 392240-94-7C14H18ClN3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-N,2-dimethylpropanamide chemical structure, C17H25N3OS, CAS 392320-83-1
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-N,2-dimethylpropanamide
CAS 392320-83-1C17H25N3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-N-methylbutanamide chemical structure, C17H25N3OS, CAS 392320-84-2
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-N-methylbutanamide
CAS 392320-84-2C17H25N3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]propanamide chemical structure, C15H21N3OS, CAS 392240-96-9
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]propanamide
CAS 392240-96-9C15H21N3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]butanamide chemical structure, C16H23N3OS, CAS 392244-10-9
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]butanamide
CAS 392244-10-9C16H23N3OS
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-N-methylpentanamide chemical structure, C18H27N3OS, CAS 392320-86-4
N-[5-(1-Adamantyl)-1,3,4-thiadiazol-2-yl]-N-methylpentanamide
CAS 392320-86-4C18H27N3OS
N-{[5-(3,5-Dimethyladamantan-1-yl)-1,3,4-thiadiazol-2-yl]methyl}ethanamine chemical structure, C17H27N3S, CAS 1539446-80-4
N-{[5-(3,5-Dimethyladamantan-1-yl)-1,3,4-thiadiazol-2-yl]methyl}ethanamine
CAS 1539446-80-4C17H27N3S
N-(5-(Adamantan-1-yl)-1,3,4-thiadiazol-2-yl)-3,7-dimethyloctanamide chemical structure, C22H35N3OS, CAS 2756347-73-4
N-(5-(Adamantan-1-yl)-1,3,4-thiadiazol-2-yl)-3,7-dimethyloctanamide
CAS 2756347-73-4C22H35N3OS