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Murcko scaffold

[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-phenylmethanone scaffold

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
10
With full pages
1
Scaffold SMILES

O=C(c1ccccc1)N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the [4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-phenylmethanone page
Murcko scaffold O=C(c1ccccc1)N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

(3,4-Dimethoxyphenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone chemical structure, C26H28N2O4, CAS 425390-39-2
(3,4-Dimethoxyphenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone
CAS 425390-39-2C26H28N2O4
(2-Fluorophenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone chemical structure, C24H23FN2O2, CAS 462098-09-5
(2-Fluorophenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone
CAS 462098-09-5C24H23FN2O2
(2-Methoxyphenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone chemical structure, C25H26N2O3, CAS 500001-65-0
(2-Methoxyphenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone
CAS 500001-65-0C25H26N2O3
[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone chemical structure, C27H30N2O5, CAS 415942-43-7
[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
CAS 415942-43-7C27H30N2O5
(2,3-Dimethoxyphenyl)[4-(3-phenoxybenzyl)piperazin-1-yl]methanone chemical structure, C26H28N2O4, CAS 423742-24-9
(2,3-Dimethoxyphenyl)[4-(3-phenoxybenzyl)piperazin-1-yl]methanone
CAS 423742-24-9C26H28N2O4
(4-Fluorophenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone chemical structure, C24H23FN2O2, CAS 6033-08-5
(4-Fluorophenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone
CAS 6033-08-5C24H23FN2O2
[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-phenylmethanone chemical structure, C24H24N2O2, CAS 425392-30-9
[4-[(3-Phenoxyphenyl)methyl]piperazin-1-yl]-phenylmethanone
CAS 425392-30-9C24H24N2O2
(3-Fluorophenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone chemical structure, C24H23FN2O2, CAS 425395-96-6
(3-Fluorophenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone
CAS 425395-96-6C24H23FN2O2
(3,5-Dimethoxyphenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone chemical structure, C26H28N2O4, CAS 415942-62-0
(3,5-Dimethoxyphenyl)-[4-[(3-phenoxyphenyl)methyl]piperazin-1-yl]methanone
CAS 415942-62-0C26H28N2O4
1-(4-Nitrobenzoyl)-4-(3-phenoxybenzyl)piperazine chemical structure, C24H23N3O4, CAS 425391-45-3
1-(4-Nitrobenzoyl)-4-(3-phenoxybenzyl)piperazine
CAS 425391-45-3C24H23N3O4