CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 27 atoms

22 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
22
With full pages
0
Scaffold SMILES

O=S(=O)(Nc1ccc(-c2ccc(N3CCCC3)nn2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccc(-c2ccc(N3CCCC3)nn2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

3-Methyl-N-[4-(6-pyrrolidin-1-ylpyridazin-3-yl)phenyl]benzenesulfonamide chemical structure, C21H22N4O2S, CAS 946317-64-2
3-Methyl-N-[4-(6-pyrrolidin-1-ylpyridazin-3-yl)phenyl]benzenesulfonamide
CAS 946317-64-2C21H22N4O2S
3-Fluoro-N-[4-(6-pyrrolidin-1-ylpyridazin-3-yl)phenyl]benzenesulfonamide chemical structure, C20H19FN4O2S, CAS 1004443-96-2
3-Fluoro-N-[4-(6-pyrrolidin-1-ylpyridazin-3-yl)phenyl]benzenesulfonamide
CAS 1004443-96-2C20H19FN4O2S
2-Chloro-5-nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C20H18ClN5O4S, CAS 941935-68-8
2-Chloro-5-nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 941935-68-8C20H18ClN5O4S
2-Nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C20H19N5O4S, CAS 898422-08-7
2-Nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 898422-08-7C20H19N5O4S
3-Nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C20H19N5O4S, CAS 941890-27-3
3-Nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 941890-27-3C20H19N5O4S
4-Nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C20H19N5O4S, CAS 898442-20-1
4-Nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 898442-20-1C20H19N5O4S
2-Methyl-5-nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C21H21N5O4S, CAS 898446-44-1
2-Methyl-5-nitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 898446-44-1C21H21N5O4S
4-Methyl-3,5-dinitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C21H20N6O6S, CAS 898442-23-4
4-Methyl-3,5-dinitro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 898442-23-4C21H20N6O6S
3-Chloro-N-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}benzene-1-sulfonamide chemical structure, C20H19ClN4O2S, CAS 904827-13-0
3-Chloro-N-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}benzene-1-sulfonamide
CAS 904827-13-0C20H19ClN4O2S
3,4-Dimethyl-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C22H24N4O2S, CAS 946287-16-7
3,4-Dimethyl-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 946287-16-7C22H24N4O2S
2,4-Dimethyl-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C22H24N4O2S, CAS 946346-63-0
2,4-Dimethyl-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 946346-63-0C22H24N4O2S
2,4,5-Trimethyl-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C23H26N4O2S, CAS 946317-68-6
2,4,5-Trimethyl-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 946317-68-6C23H26N4O2S
4-Chloro-2,5-dimethyl-N-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}benzene-1-sulfonamide chemical structure, C22H23ClN4O2S, CAS 946287-20-3
4-Chloro-2,5-dimethyl-N-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}benzene-1-sulfonamide
CAS 946287-20-3C22H23ClN4O2S
5-Fluoro-2-methoxy-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C21H21FN4O3S, CAS 946317-72-2
5-Fluoro-2-methoxy-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 946317-72-2C21H21FN4O3S
4-Methoxy-2,3,5-trimethyl-N-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}benzene-1-sulfonamide chemical structure, C24H28N4O3S, CAS 946207-11-0
4-Methoxy-2,3,5-trimethyl-N-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}benzene-1-sulfonamide
CAS 946207-11-0C24H28N4O3S
3,5-Dimethyl-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C22H24N4O2S, CAS 946307-07-9
3,5-Dimethyl-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 946307-07-9C22H24N4O2S
2-Chloro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)-5-(trifluoromethyl)benzenesulfonamide chemical structure, C21H18ClF3N4O2S, CAS 946275-13-4
2-Chloro-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)-5-(trifluoromethyl)benzenesulfonamide
CAS 946275-13-4C21H18ClF3N4O2S
N-(4-(6-(Pyrrolidin-1-yl)pyridazin-3-yl)phenyl)-2-(trifluoromethyl)benzenesulfonamide chemical structure, C21H19F3N4O2S, CAS 946307-03-5
N-(4-(6-(Pyrrolidin-1-yl)pyridazin-3-yl)phenyl)-2-(trifluoromethyl)benzenesulfonamide
CAS 946307-03-5C21H19F3N4O2S
2-Ethoxy-5-(propan-2-yl)-N-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}benzene-1-sulfonamide chemical structure, C25H30N4O3S, CAS 946358-62-9
2-Ethoxy-5-(propan-2-yl)-N-{4-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}benzene-1-sulfonamide
CAS 946358-62-9C25H30N4O3S
2,5-Dimethoxy-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide chemical structure, C22H24N4O4S, CAS 1172294-54-0
2,5-Dimethoxy-N-(4-(6-(pyrrolidin-1-yl)pyridazin-3-yl)phenyl)benzenesulfonamide
CAS 1172294-54-0C22H24N4O4S
4-Fluoro-N-[4-(6-pyrrolidin-1-ylpyridazin-3-yl)phenyl]-3-(trifluoromethyl)benzenesulfonamide chemical structure, C21H18F4N4O2S, CAS 1172362-44-5
4-Fluoro-N-[4-(6-pyrrolidin-1-ylpyridazin-3-yl)phenyl]-3-(trifluoromethyl)benzenesulfonamide
CAS 1172362-44-5C21H18F4N4O2S
4-Methoxy-2,5-dimethyl-N-[4-(6-pyrrolidin-1-ylpyridazin-3-yl)phenyl]benzenesulfonamide chemical structure, C23H26N4O3S, CAS 1171679-01-8
4-Methoxy-2,5-dimethyl-N-[4-(6-pyrrolidin-1-ylpyridazin-3-yl)phenyl]benzenesulfonamide
CAS 1171679-01-8C23H26N4O3S