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Murcko scaffold

Ring system with 4 rings and 24 atoms

19 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
19
With full pages
7
Scaffold SMILES

c1ccc(-c2cnn3c(NCCCn4ccnc4)ccnc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cnn3c(NCCCn4ccnc4)ccnc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-[3-(1H-Imidazol-1-yl)propyl]-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H20N6, CAS 850238-44-7
N-[3-(1H-Imidazol-1-yl)propyl]-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 850238-44-7C19H20N6
5-tert-Butyl-3-(4-chlorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]-2-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H27ClN6, CAS 862244-54-0
5-tert-Butyl-3-(4-chlorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]-2-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 862244-54-0C23H27ClN6
5-tert-Butyl-N-[3-(1H-imidazol-1-yl)propyl]-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H28N6, CAS 850899-81-9
5-tert-Butyl-N-[3-(1H-imidazol-1-yl)propyl]-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 850899-81-9C23H28N6
3-(4-Chlorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H21ClN6, CAS 877783-50-1
3-(4-Chlorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877783-50-1C20H21ClN6
N-(3-Imidazol-1-ylpropyl)-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H22N6, CAS 850751-43-8
N-(3-Imidazol-1-ylpropyl)-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 850751-43-8C20H22N6
N-[3-(1H-Imidazol-1-yl)propyl]-2-methyl-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H26N6, CAS 896596-79-5
N-[3-(1H-Imidazol-1-yl)propyl]-2-methyl-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 896596-79-5C22H26N6
3-(4-Chlorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]-5-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H19ClN6, CAS 896808-01-8
3-(4-Chlorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]-5-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896808-01-8C19H19ClN6
N-[3-(1-Imidazolyl)propyl]-2-methyl-3-phenyl-5-propyl-7-pyrazolo[1,5-a]pyrimidinamine chemical structure, C22H26N6, CAS 896827-55-7
N-[3-(1-Imidazolyl)propyl]-2-methyl-3-phenyl-5-propyl-7-pyrazolo[1,5-a]pyrimidinamine
CAS 896827-55-7C22H26N6
5-tert-Butyl-N-[3-(1H-imidazol-1-yl)propyl]-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H26N6, CAS 896846-65-4
5-tert-Butyl-N-[3-(1H-imidazol-1-yl)propyl]-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896846-65-4C22H26N6
5-tert-Butyl-3-(2-chlorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H25ClN6, CAS 902039-40-1
5-tert-Butyl-3-(2-chlorophenyl)-N-[3-(1H-imidazol-1-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS 902039-40-1C22H25ClN6
5-tert-Butyl-3-(4-chlorophenyl)-N-(3-imidazol-1-ylpropyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H25ClN6, CAS 899393-92-1
5-tert-Butyl-3-(4-chlorophenyl)-N-(3-imidazol-1-ylpropyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 899393-92-1C22H25ClN6
N-[3-(1H-Imidazol-1-yl)propyl]-3-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H22N6O, CAS 902022-17-7
N-[3-(1H-Imidazol-1-yl)propyl]-3-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 902022-17-7C20H22N6O
2-Ethyl-N-[3-(1H-imidazol-1-yl)propyl]-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H24N6, CAS 900889-69-2
2-Ethyl-N-[3-(1H-imidazol-1-yl)propyl]-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 900889-69-2C21H24N6
N-[3-(1H-Imidazol-1-yl)propyl]-5-methyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H22N6, CAS 900890-21-3
N-[3-(1H-Imidazol-1-yl)propyl]-5-methyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900890-21-3C20H22N6
N-[3-(1H-Imidazol-1-yl)propyl]-5-methyl-3-phenyl-6-(prop-2-en-1-yl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H24N6, CAS 900889-27-2
N-[3-(1H-Imidazol-1-yl)propyl]-5-methyl-3-phenyl-6-(prop-2-en-1-yl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900889-27-2C22H24N6
N-[3-(1H-Imidazol-1-yl)propyl]-5,6-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H22N6, CAS 900888-30-4
N-[3-(1H-Imidazol-1-yl)propyl]-5,6-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 900888-30-4C20H22N6
N-[3-(1H-Imidazol-1-yl)propyl]-5-methyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H19F3N6, CAS 900882-66-8
N-[3-(1H-Imidazol-1-yl)propyl]-5-methyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900882-66-8C20H19F3N6
N-(3-(1H-Imidazol-1-yl)propyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H24N6O, CAS 879762-27-3
N-(3-(1H-Imidazol-1-yl)propyl)-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 879762-27-3C21H24N6O
N-(3-Imidazol-1-ylpropyl)-2,5-dimethyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H24N6, CAS 900293-01-8
N-(3-Imidazol-1-ylpropyl)-2,5-dimethyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900293-01-8C21H24N6