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Murcko scaffold

Ring system with 3 rings and 29 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
29
Chemicals
13
With full pages
12
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NN=Cc1ccc(OCc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)c1ccccc1)NN=Cc1ccc(OCc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-3,4-dimethoxybenzamide chemical structure, C25H25N3O5, CAS 330629-17-9
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-3,4-dimethoxybenzamide
CAS 330629-17-9C25H25N3O5
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-2-methylbenzamide chemical structure, C24H23N3O3, CAS 444178-76-1
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-2-methylbenzamide
CAS 444178-76-1C24H23N3O3
2-CL-N-(2-(2-(4-((4-Chlorobenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C23H19Cl2N3O3, CAS 764653-85-2
2-CL-N-(2-(2-(4-((4-Chlorobenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide
CAS 764653-85-2C23H19Cl2N3O3
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-4-methoxybenzamide chemical structure, C24H23N3O4, CAS 769150-59-6
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-4-methoxybenzamide
CAS 769150-59-6C24H23N3O4
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-3,4-dichlorobenzamide chemical structure, C23H19Cl2N3O3, CAS 765284-47-7
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-3,4-dichlorobenzamide
CAS 765284-47-7C23H19Cl2N3O3
N-(2-{(2E)-2-[4-(benzyloxy)benzylidene]hydrazino}-2-oxoethyl)-2-iodobenzamide chemical structure, C23H20IN3O3, CAS 769148-76-7
N-(2-{(2E)-2-[4-(benzyloxy)benzylidene]hydrazino}-2-oxoethyl)-2-iodobenzamide
CAS 769148-76-7C23H20IN3O3
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-4-fluorobenzamide chemical structure, C23H20FN3O3, CAS 765276-45-7
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-4-fluorobenzamide
CAS 765276-45-7C23H20FN3O3
3-ME-N-(2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C25H25N3O3, CAS 444652-67-9
3-ME-N-(2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide
CAS 444652-67-9C25H25N3O3
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-4-ethoxybenzamide chemical structure, C25H25N3O4, CAS 764653-01-2
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-4-ethoxybenzamide
CAS 764653-01-2C25H25N3O4
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-3-bromobenzamide chemical structure, C23H20BrN3O3, CAS 769155-94-4
N-(2-(2-(4-(Benzyloxy)benzylidene)hydrazino)-2-oxoethyl)-3-bromobenzamide
CAS 769155-94-4C23H20BrN3O3
2-CL-N-(2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C24H22ClN3O3, CAS 528533-52-0
2-CL-N-(2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide
CAS 528533-52-0C24H22ClN3O3
3-CL-N-(2-(2-(4-((4-Chlorobenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C23H19Cl2N3O3, CAS 765286-12-2
3-CL-N-(2-(2-(4-((4-Chlorobenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide
CAS 765286-12-2C23H19Cl2N3O3
4-CL-N-(2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide chemical structure, C24H22ClN3O3, CAS 881469-99-4
4-CL-N-(2-(2-(4-((4-Methylbenzyl)oxy)benzylidene)hydrazino)-2-oxoethyl)benzamide
CAS 881469-99-4C24H22ClN3O3