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Murcko scaffold

Ring system with 3 rings and 25 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
11
With full pages
1
Scaffold SMILES

C(=Cc1cnnc(SCc2ccccc2)n1)NOCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1cnnc(SCc2ccccc2)n1)NOCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

3-(Benzylsulfanyl)-5-(2-(((2,3-dichlorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine chemical structure, C20H18Cl2N4OS, CAS 338775-75-0
3-(Benzylsulfanyl)-5-(2-(((2,3-dichlorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine
CAS 338775-75-0C20H18Cl2N4OS
(E)-2-(3-Benzylsulfanyl-6-methyl-1,2,4-triazin-5-yl)-N-[(2,6-dichlorophenyl)methoxy]ethenamine chemical structure, C20H18Cl2N4OS, CAS 400078-26-4
(E)-2-(3-Benzylsulfanyl-6-methyl-1,2,4-triazin-5-yl)-N-[(2,6-dichlorophenyl)methoxy]ethenamine
CAS 400078-26-4C20H18Cl2N4OS
3-(Benzylsulfanyl)-5-(2-(((4-chlorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine chemical structure, C20H19ClN4OS, CAS 477866-54-9
3-(Benzylsulfanyl)-5-(2-(((4-chlorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine
CAS 477866-54-9C20H19ClN4OS
(E)-N-[(4-tert-Butylphenyl)methoxy]-2-[3-[(4-chlorophenyl)methylsulfanyl]-6-methyl-1,2,4-triazin-5-yl]ethenamine chemical structure, C24H27ClN4OS, CAS 338775-77-2
(E)-N-[(4-tert-Butylphenyl)methoxy]-2-[3-[(4-chlorophenyl)methylsulfanyl]-6-methyl-1,2,4-triazin-5-yl]ethenamine
CAS 338775-77-2C24H27ClN4OS
3-(Benzylsulfanyl)-5-(2-(((4-fluorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine chemical structure, C20H19FN4OS, CAS 477866-63-0
3-(Benzylsulfanyl)-5-(2-(((4-fluorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine
CAS 477866-63-0C20H19FN4OS
3-((4-Chlorobenzyl)sulfanyl)-5-(2-(((4-fluorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine chemical structure, C20H18ClFN4OS, CAS 338775-67-0
3-((4-Chlorobenzyl)sulfanyl)-5-(2-(((4-fluorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine
CAS 338775-67-0C20H18ClFN4OS
(E)-2-[3-[(4-Chlorophenyl)methylsulfanyl]-6-methyl-1,2,4-triazin-5-yl]-N-[(2,4-dichlorophenyl)methoxy]ethenamine chemical structure, C20H17Cl3N4OS, CAS 477866-61-8
(E)-2-[3-[(4-Chlorophenyl)methylsulfanyl]-6-methyl-1,2,4-triazin-5-yl]-N-[(2,4-dichlorophenyl)methoxy]ethenamine
CAS 477866-61-8C20H17Cl3N4OS
3-((4-Chlorobenzyl)sulfanyl)-5-(2-(((3-fluorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine chemical structure, C20H18ClFN4OS, CAS 338775-71-6
3-((4-Chlorobenzyl)sulfanyl)-5-(2-(((3-fluorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine
CAS 338775-71-6C20H18ClFN4OS
3-((4-Chlorobenzyl)sulfanyl)-5-(2-(((2,3-dichlorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine chemical structure, C20H17Cl3N4OS, CAS 338775-65-8
3-((4-Chlorobenzyl)sulfanyl)-5-(2-(((2,3-dichlorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine
CAS 338775-65-8C20H17Cl3N4OS
3-((4-Chlorobenzyl)sulfanyl)-6-methyl-5-(2-(((4-methylbenzyl)oxy)amino)vinyl)-1,2,4-triazine chemical structure, C21H21ClN4OS, CAS 338775-69-2
3-((4-Chlorobenzyl)sulfanyl)-6-methyl-5-(2-(((4-methylbenzyl)oxy)amino)vinyl)-1,2,4-triazine
CAS 338775-69-2C21H21ClN4OS
3-(Benzylsulfanyl)-5-(2-(((2,4-dichlorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine chemical structure, C20H18Cl2N4OS, CAS 1164493-74-6
3-(Benzylsulfanyl)-5-(2-(((2,4-dichlorobenzyl)oxy)amino)vinyl)-6-methyl-1,2,4-triazine
CAS 1164493-74-6C20H18Cl2N4OS