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Murcko scaffold

Ring system with 2 rings and 16 atoms

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
19
With full pages
3
Scaffold SMILES

O=c1ccn(CCc2ccccc2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(CCc2ccccc2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

6-Amino-1-[2-(3,4-dimethoxyphenyl)ethyl]-2,4(1H,3H)-pyrimidinedione chemical structure, C14H17N3O4, CAS 446266-76-8
6-Amino-1-[2-(3,4-dimethoxyphenyl)ethyl]-2,4(1H,3H)-pyrimidinedione
CAS 446266-76-8C14H17N3O4
6-Amino-1-(2-phenylethyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C12H13N3O2, CAS 54052-76-5
6-Amino-1-(2-phenylethyl)pyrimidine-2,4(1H,3H)-dione
CAS 54052-76-5C12H13N3O2
1-(3,4-Dimethoxyphenethyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile chemical structure, C15H15N3O4, CAS 133181-42-7
1-(3,4-Dimethoxyphenethyl)-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile
CAS 133181-42-7C15H15N3O4
6-Amino-5-bromo-1-[2-(3,4-dimethoxyphenyl)ethyl]pyrimidine-2,4-dione chemical structure, C14H16BrN3O4, CAS 838875-24-4
6-Amino-5-bromo-1-[2-(3,4-dimethoxyphenyl)ethyl]pyrimidine-2,4-dione
CAS 838875-24-4C14H16BrN3O4
2,4(1H,3H)-Pyrimidinedione, 1-(2-(3-methyl-4-(1-methylethoxy)phenyl)ethyl)- chemical structure, C16H20N2O3, CAS 88655-26-9
2,4(1H,3H)-Pyrimidinedione, 1-(2-(3-methyl-4-(1-methylethoxy)phenyl)ethyl)-
CAS 88655-26-9C16H20N2O3
6-Amino-2,4-dioxo-1-phenethyl-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde chemical structure, C13H13N3O3, CAS 919724-65-5
6-Amino-2,4-dioxo-1-phenethyl-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
CAS 919724-65-5C13H13N3O3
6-Amino-1-(4-methoxyphenethyl)pyrimidine-2,4(1H,3H)-dione chemical structure, C13H15N3O3, CAS 158893-37-9
6-Amino-1-(4-methoxyphenethyl)pyrimidine-2,4(1H,3H)-dione
CAS 158893-37-9C13H15N3O3
6-Amino-5-nitroso-1-phenethylpyrimidine-2,4(1H,3H)-dione chemical structure, C12H12N4O3, CAS 1055299-81-4
6-Amino-5-nitroso-1-phenethylpyrimidine-2,4(1H,3H)-dione
CAS 1055299-81-4C12H12N4O3
5,6-Diamino-1-phenethylpyrimidine-2,4(1H,3H)-dione chemical structure, C12H14N4O2, CAS 937600-08-3
5,6-Diamino-1-phenethylpyrimidine-2,4(1H,3H)-dione
CAS 937600-08-3C12H14N4O2
3-Methyl-1-(2-phenylethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C13H14N2O2, CAS 2436631-69-3
3-Methyl-1-(2-phenylethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436631-69-3C13H14N2O2
1-[2-(4-Methoxyphenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C14H16N2O3, CAS 2436631-73-9
1-[2-(4-Methoxyphenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436631-73-9C14H16N2O3
1-[2-(2-Methoxyphenyl)ethyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C13H14N2O3, CAS 2436631-98-8
1-[2-(2-Methoxyphenyl)ethyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436631-98-8C13H14N2O3
1-[2-(2-Methoxyphenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C14H16N2O3, CAS 2436338-59-7
1-[2-(2-Methoxyphenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436338-59-7C14H16N2O3
1-[2-(3-Methoxyphenyl)ethyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C13H14N2O3, CAS 2446487-33-6
1-[2-(3-Methoxyphenyl)ethyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2446487-33-6C13H14N2O3
1-[2-(3-Methoxyphenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C14H16N2O3, CAS 2436632-18-5
1-[2-(3-Methoxyphenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436632-18-5C14H16N2O3
1-[2-(4-Chlorophenyl)ethyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C12H11ClN2O2, CAS 2436575-11-8
1-[2-(4-Chlorophenyl)ethyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436575-11-8C12H11ClN2O2
1-[2-(4-Chlorophenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C13H13ClN2O2, CAS 2436338-84-8
1-[2-(4-Chlorophenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436338-84-8C13H13ClN2O2
1-[2-(4-Fluorophenyl)ethyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C12H11FN2O2, CAS 2436338-94-0
1-[2-(4-Fluorophenyl)ethyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436338-94-0C12H11FN2O2
1-[2-(4-Fluorophenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C13H13FN2O2, CAS 2436575-16-3
1-[2-(4-Fluorophenyl)ethyl]-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 2436575-16-3C13H13FN2O2