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Murcko scaffold

Ring system with 6 rings and 20 atoms

32 chemicals on CompoundList share this ring system.

Rings
6
Scaffold atoms
20
Chemicals
32
With full pages
1
Scaffold SMILES

C=C1CN2C3CC45CC1CC2C4(Nc1ccccc15)O3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1CN2C3CC45CC1CC2C4(Nc1ccccc15)O3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

Norquaternine chemical structure, C22H26N2O5, CAS 74991-69-8
Norquaternine
CAS 74991-69-8C22H26N2O5
Alstopicralamine chemical structure, C23H28N2O5, CAS 57499-02-2
Alstopicralamine
CAS 57499-02-2C23H28N2O5
Picraline, 16-de(acetoxymethyl)-16-formyl- chemical structure, C21H22N2O4
Picraline, 16-de(acetoxymethyl)-16-formyl-
C21H22N2O4
Methyl (1R,9S,11S,14E,15S,17S)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C21H22N2O4
Methyl (1R,9S,11S,14E,15S,17S)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C21H22N2O4
Picralinal chemical structure, C21H22N2O4, CAS 20045-06-1
Picralinal
CAS 20045-06-1C21H22N2O4
Picrinine chemical structure, C20H22N2O3, CAS 4684-32-6
Picrinine
CAS 4684-32-6C20H22N2O3
Methyl 14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C21H22N2O4
Methyl 14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C21H22N2O4
Picraline chemical structure, C23H26N2O5
Picraline
C23H26N2O5
Methyl (1R,9R,11S,14E,17S)-14-ethylidene-2-(methoxymethyl)-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C22H26N2O4
Methyl (1R,9R,11S,14E,17S)-14-ethylidene-2-(methoxymethyl)-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C22H26N2O4
Methyl (1R,9S,11S,14E,17S)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C21H22N2O4
Methyl (1R,9S,11S,14E,17S)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C21H22N2O4
Methyl (1R,9S,11S,14E,15R,17S)-19-(acetyloxymethyl)-14-ethylidene-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C23H26N2O5
Methyl (1R,9S,11S,14E,15R,17S)-19-(acetyloxymethyl)-14-ethylidene-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C23H26N2O5
Methyl (1R,9R,11S,14E,15S,17S)-14-ethylidene-2-(methoxymethyl)-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C22H26N2O4
Methyl (1R,9R,11S,14E,15S,17S)-14-ethylidene-2-(methoxymethyl)-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C22H26N2O4
Methyl (1R,9S,11S,14E,15R,17S)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C21H22N2O4
Methyl (1R,9S,11S,14E,15R,17S)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C21H22N2O4
Picraline chemical structure, C23H26N2O5, CAS 2671-32-1
Picraline
CAS 2671-32-1C23H26N2O5
N1-Methoxymethyl picrinine chemical structure, C22H26N2O4, CAS 1158845-78-3
N1-Methoxymethyl picrinine
CAS 1158845-78-3C22H26N2O4
Rauvoyunine B chemical structure, C23H26N2O6, CAS 1414883-82-1
Rauvoyunine B
CAS 1414883-82-1C23H26N2O6
Methyl (1R,9R,11S,15S,17S)-14-ethylidene-2-(methoxymethyl)-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C22H26N2O4
Methyl (1R,9R,11S,15S,17S)-14-ethylidene-2-(methoxymethyl)-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C22H26N2O4
Rauvoyunine B chemical structure, C23H26N2O6
Rauvoyunine B
C23H26N2O6
Picraline chemical structure, C23H26N2O5
Picraline
C23H26N2O5
Methyl (1R,9S,19R)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C21H22N2O4
Methyl (1R,9S,19R)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C21H22N2O4
Methyl 19-(acetyloxymethyl)-14-ethylidene-5-hydroxy-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3(8),4,6-triene-19-carboxylate chemical structure, C23H26N2O6
Methyl 19-(acetyloxymethyl)-14-ethylidene-5-hydroxy-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3(8),4,6-triene-19-carboxylate
C23H26N2O6
Methyl (1R,9S,11S,14E,15S,17S,19S)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate chemical structure, C21H22N2O4
Methyl (1R,9S,11S,14E,15S,17S,19S)-14-ethylidene-19-formyl-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate
C21H22N2O4
Methyl (14Z)-19-(acetyloxymethyl)-14-ethylidene-5-hydroxy-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3(8),4,6-triene-19-carboxylate chemical structure, C23H26N2O6
Methyl (14Z)-19-(acetyloxymethyl)-14-ethylidene-5-hydroxy-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3(8),4,6-triene-19-carboxylate
C23H26N2O6
Rauvoyunine B chemical structure, C23H26N2O6
Rauvoyunine B
C23H26N2O6