Murcko scaffold

N-Benzyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide scaffold

12 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 12
With full pages: 11

Scaffold SMILES

O=C1CCc2cc(S(=O)(=O)NCc3ccccc3)cc3c2N1CC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-Benzyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide page

Murcko scaffold O=C1CCc2cc(S(=O)(=O)NCc3ccccc3)cc3c2N1CC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

$N-Benzyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C18H18N2O3S, CAS 898462-40-3$

N-Benzyl-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-40-3C₁₈H₁₈N₂O₃S

$N-[(4-Methylphenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C19H20N2O3S, CAS 898419-39-1$

N-[(4-Methylphenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898419-39-1C₁₉H₂₀N₂O₃S

$N-[(4-Chlorophenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C18H17ClN2O3S, CAS 898462-45-8$

N-[(4-Chlorophenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-45-8C₁₈H₁₇ClN₂O₃S

$N-Benzyl-11-oxo-N-(propan-2-yl)-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C21H24N2O3S, CAS 898462-42-5$

N-Benzyl-11-oxo-N-(propan-2-yl)-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-42-5C₂₁H₂₄N₂O₃S

N-Benzyl-N-methyl-4-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898435-89-7C₁₉H₂₀N₂O₃S

N-(4-Fluorobenzyl)-4-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898462-56-1C₁₈H₁₇FN₂O₃S

N-Benzyl-N-ethyl-4-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinoline-8-sulfonamide

CAS 898462-58-3C₂₀H₂₂N₂O₃S

$N-[(4-Methoxyphenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C19H20N2O4S, CAS 898462-66-3$

N-[(4-Methoxyphenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-66-3C₁₉H₂₀N₂O₄S

$N-[(3-Methoxyphenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C19H20N2O4S, CAS 898462-84-5$

N-[(3-Methoxyphenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide

CAS 898462-84-5C₁₉H₂₀N₂O₄S

$N-[(2-Methoxyphenyl)methyl]-11-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-triene-6-sulfonamide chemical structure, C19H20N2O4S, CAS 898419-78-8$