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Murcko scaffold

Ring system with 4 rings and 20 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
6
With full pages
3
Scaffold SMILES

O=C1C(Cc2c[nH]cn2)CCc2cc3ccccc3n21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(Cc2c[nH]cn2)CCc2cc3ccccc3n21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

FK 1052 chemical structure, C18H19N3O, CAS 129299-72-5
FK 1052
CAS 129299-72-5C18H19N3O
Fabesetron hydrochloride chemical structure, C18H20ClN3O, CAS 129299-90-7
Fabesetron hydrochloride
CAS 129299-90-7C18H20ClN3O
Fabesetron chemical structure, C18H19N3O, CAS 129300-27-2
Fabesetron
CAS 129300-27-2C18H19N3O
Pyrido[1,2-a]indol-6(7H)-one, 8,9-dihydro-10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-, (S)- chemical structure, C18H19N3O, CAS 129299-89-4
Pyrido[1,2-a]indol-6(7H)-one, 8,9-dihydro-10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-, (S)-
CAS 129299-89-4C18H19N3O
FK1052 hydrochloride chemical structure, C18H20ClN3O, CAS 129299-81-6
FK1052 hydrochloride
CAS 129299-81-6C18H20ClN3O
(7s)-10-Methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-8,9-dihydro-7H-pyrido[1,2-a]indol-6-one hydrochloride chemical structure, C18H20ClN3O, CAS 129299-88-3
(7s)-10-Methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]-8,9-dihydro-7H-pyrido[1,2-a]indol-6-one hydrochloride
CAS 129299-88-3C18H20ClN3O