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Murcko scaffold

Ring system with 5 rings and 33 atoms

7 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
33
Chemicals
7
With full pages
2
Scaffold SMILES

O=c1ccn(C2CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CCO2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2CN(C(c3ccccc3)(c3ccccc3)c3ccccc3)CCO2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

1-((2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl)-5-methyl-2,4(1H,3H)-pyrimidinedione chemical structure, C29H29N3O4, CAS 914361-76-5
1-((2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
CAS 914361-76-5C29H29N3O4
(6-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate) chemical structure, C31H34ClN4O5P, CAS 956139-30-3
(6-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate)
CAS 956139-30-3C31H34ClN4O5P
1-(6-(Hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C29H29N3O4, CAS 1265140-28-0
1-(6-(Hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
CAS 1265140-28-0C29H29N3O4
((2S,6R)-6-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate chemical structure, C31H34ClN4O5P, CAS 1155373-34-4
((2S,6R)-6-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
CAS 1155373-34-4C31H34ClN4O5P
N-Trityl-morpholino-T-5'-O-phosphoramidite chemical structure, C38H46N5O5P, CAS 2434654-73-4
N-Trityl-morpholino-T-5'-O-phosphoramidite
CAS 2434654-73-4C38H46N5O5P
Tr-morpholino-U chemical structure, C28H27N3O4, CAS 139323-52-7
Tr-morpholino-U
CAS 139323-52-7C28H27N3O4
Morpholino U subunit chemical structure, C30H32ClN4O5P, CAS 2388517-98-2
Morpholino U subunit
CAS 2388517-98-2C30H32ClN4O5P