CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 21 atoms

27 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
27
With full pages
3
Scaffold SMILES

c1cncc(CCn2c3c(c4ccccc42)CNCC3)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cncc(CCn2c3c(c4ccccc42)CNCC3)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

Dorastine chemical structure, C20H22ClN3, CAS 21228-13-7
Dorastine
CAS 21228-13-7C20H22ClN3
Latrepirdine chemical structure, C21H25N3, CAS 3613-73-8
Latrepirdine
CAS 3613-73-8C21H25N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-5-(2-(6-methyl-3-pyridyl)ethyl)-2-propyl- chemical structure, C22H27N3, CAS 20674-92-4
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-5-(2-(6-methyl-3-pyridyl)ethyl)-2-propyl-
CAS 20674-92-4C22H27N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-2-propyl- chemical structure, C23H29N3, CAS 20674-93-5
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-2-propyl-
CAS 20674-93-5C23H29N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-butyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C23H29N3, CAS 20674-94-6
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-butyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20674-94-6C23H29N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-butyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C24H31N3, CAS 20674-95-7
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-butyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20674-95-7C24H31N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-isobutyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C23H29N3, CAS 20674-97-9
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-isobutyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20674-97-9C23H29N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-isobutyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C24H31N3, CAS 20674-98-0
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-isobutyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20674-98-0C24H31N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-butyl-4-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C24H31N3, CAS 20674-99-1
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-butyl-4-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20674-99-1C24H31N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-sec-butyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C24H31N3, CAS 20675-00-7
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-sec-butyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20675-00-7C24H31N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-isopentyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C24H31N3, CAS 20675-01-8
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-isopentyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20675-01-8C24H31N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-isopentyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C25H33N3, CAS 20675-02-9
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-isopentyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20675-02-9C25H33N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-ethyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C21H25N3, CAS 20771-45-3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-ethyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20771-45-3C21H25N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-8-methoxy-5-(2-(6-methyl-3-pyridyl)ethyl)-2-propyl- chemical structure, C23H29N3O, CAS 20771-46-4
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-8-methoxy-5-(2-(6-methyl-3-pyridyl)ethyl)-2-propyl-
CAS 20771-46-4C23H29N3O
2,3,4,5-Tetrahydro-2-sec-butyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido(4,3-b)indole chemical structure, C23H29N3, CAS 20771-47-5
2,3,4,5-Tetrahydro-2-sec-butyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido(4,3-b)indole
CAS 20771-47-5C23H29N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-heptyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C26H35N3, CAS 20771-48-6
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-heptyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20771-48-6C26H35N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-heptyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C27H37N3, CAS 20771-49-7
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-heptyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20771-49-7C27H37N3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-heptyl-8-methoxy-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C27H37N3O, CAS 20771-50-0
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-heptyl-8-methoxy-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 20771-50-0C27H37N3O
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-ethyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-, hydrochloride chemical structure, C22H28ClN3, CAS 25390-47-0
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-ethyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-, hydrochloride
CAS 25390-47-0C22H28ClN3
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-ethyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)- chemical structure, C22H27N3, CAS 102207-58-9
1H-Pyrido(4,3-b)indole, 2,3,4,5-tetrahydro-2-ethyl-8-methyl-5-(2-(6-methyl-3-pyridyl)ethyl)-
CAS 102207-58-9C22H27N3
Dorastine hydrochloride chemical structure, C20H24Cl3N3, CAS 21228-28-4
Dorastine hydrochloride
CAS 21228-28-4C20H24Cl3N3
Latrepirdine dihydrochloride chemical structure, C21H27Cl2N3, CAS 97657-92-6
Latrepirdine dihydrochloride
CAS 97657-92-6C21H27Cl2N3
Dimebolin hydrochloride chemical structure, C21H26ClN3, CAS 14292-23-0
Dimebolin hydrochloride
CAS 14292-23-0C21H26ClN3
8-Methyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole chemical structure, C20H23N3, CAS 23224-24-0
8-Methyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
CAS 23224-24-0C20H23N3