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Murcko scaffold

Ring system with 4 rings and 22 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
10
With full pages
1
Scaffold SMILES

c1ccc(Nc2ccc3ncc(-c4cn[nH]c4)nc3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ccc3ncc(-c4cn[nH]c4)nc3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-((3,5-Dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol chemical structure, C22H23N5O3, CAS 1346242-78-1
2-((3,5-Dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol
CAS 1346242-78-1C22H23N5O3
Erdafitinib impurity 13 chemical structure, C22H24N6O2, CAS 1346244-83-4
Erdafitinib impurity 13
CAS 1346244-83-4C22H24N6O2
Erdafitinib chemical structure, C25H30N6O2, CAS 1346242-81-6
Erdafitinib
CAS 1346242-81-6C25H30N6O2
Erdafitinib impurity 11 chemical structure, C24H28N6O2, CAS 1346243-54-6
Erdafitinib impurity 11
CAS 1346243-54-6C24H28N6O2
N-(3,5-Dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine chemical structure, C20H19N5O2, CAS 1346133-39-8
N-(3,5-Dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
CAS 1346133-39-8C20H19N5O2
N~2~-(2-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}ethyl)glycinamide chemical structure, C24H27N7O3, CAS 1346252-32-1
N~2~-(2-{(3,5-Dimethoxyphenyl)[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]amino}ethyl)glycinamide
CAS 1346252-32-1C24H27N7O3
2-((3,5-Dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl methanesulfonate chemical structure, C23H25N5O5S, CAS 1346245-10-0
2-((3,5-Dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl methanesulfonate
CAS 1346245-10-0C23H25N5O5S
N-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine chemical structure, C28H37N5O3Si, CAS 1346245-08-6
N-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
CAS 1346245-08-6C28H37N5O3Si
Hdac-IN-50 chemical structure, C31H41N7O4, CAS 2653339-26-3
Hdac-IN-50
CAS 2653339-26-3C31H41N7O4
Deuterated erdafitinib chemical structure, C25H30N6O2, CAS 3085640-02-1
Deuterated erdafitinib
CAS 3085640-02-1C25H30N6O2