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Murcko scaffold

Ring system with 4 rings and 22 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
11
With full pages
4
Scaffold SMILES

O=C(NC1CC1)c1cc(-c2ccccc2)nc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CC1)c1cc(-c2ccccc2)nc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-Cyclopropyl-2-(4-methylphenyl)quinoline-4-carboxamide chemical structure, C20H18N2O, CAS 389080-15-3
N-Cyclopropyl-2-(4-methylphenyl)quinoline-4-carboxamide
CAS 389080-15-3C20H18N2O
N-Cyclopropyl-2-(4-methoxyphenyl)quinoline-4-carboxamide chemical structure, C20H18N2O2, CAS 544681-12-1
N-Cyclopropyl-2-(4-methoxyphenyl)quinoline-4-carboxamide
CAS 544681-12-1C20H18N2O2
N-Cyclopropyl-2-(4-ethoxyphenyl)quinoline-4-carboxamide chemical structure, C21H20N2O2, CAS 352679-14-2
N-Cyclopropyl-2-(4-ethoxyphenyl)quinoline-4-carboxamide
CAS 352679-14-2C21H20N2O2
N-Cyclopropyl-2-(2,4-dimethylphenyl)quinoline-4-carboxamide chemical structure, C21H20N2O, CAS 545365-68-2
N-Cyclopropyl-2-(2,4-dimethylphenyl)quinoline-4-carboxamide
CAS 545365-68-2C21H20N2O
N-Cyclopropyl-2-(4-ethylphenyl)quinoline-4-carboxamide chemical structure, C21H20N2O, CAS 303135-31-1
N-Cyclopropyl-2-(4-ethylphenyl)quinoline-4-carboxamide
CAS 303135-31-1C21H20N2O
6-Bromo-N-cyclopropyl-2-(2,5-dimethylphenyl)quinoline-4-carboxamide chemical structure, C21H19BrN2O, CAS 444931-87-7
6-Bromo-N-cyclopropyl-2-(2,5-dimethylphenyl)quinoline-4-carboxamide
CAS 444931-87-7C21H19BrN2O
2-(4-Bromophenyl)-N-cyclopropyl-4-quinolinecarboxamide chemical structure, C19H15BrN2O, CAS 438474-24-9
2-(4-Bromophenyl)-N-cyclopropyl-4-quinolinecarboxamide
CAS 438474-24-9C19H15BrN2O
N-Cyclopropyl-2-(3-methoxyphenyl)quinoline-4-carboxamide chemical structure, C20H18N2O2, CAS 541544-16-5
N-Cyclopropyl-2-(3-methoxyphenyl)quinoline-4-carboxamide
CAS 541544-16-5C20H18N2O2
6-Chloro-N-cyclopropyl-2-(2-methylphenyl)quinoline-4-carboxamide chemical structure, C20H17ClN2O, CAS 713117-80-7
6-Chloro-N-cyclopropyl-2-(2-methylphenyl)quinoline-4-carboxamide
CAS 713117-80-7C20H17ClN2O
N-Cyclopropyl-2-(3,4-dimethoxyphenyl)quinoline-4-carboxamide chemical structure, C21H20N2O3, CAS 545348-85-4
N-Cyclopropyl-2-(3,4-dimethoxyphenyl)quinoline-4-carboxamide
CAS 545348-85-4C21H20N2O3
8-Chloro-N-cyclopropyl-2-(2-methylphenyl)quinoline-4-carboxamide chemical structure, C20H17ClN2O, CAS 667440-24-6
8-Chloro-N-cyclopropyl-2-(2-methylphenyl)quinoline-4-carboxamide
CAS 667440-24-6C20H17ClN2O